All Outputs (34)

Gene pathway development in human epicardial adipose tissue during early life (2016)
Journal Article

Studies in rodents and newborn humans demonstrate the influence of brown adipose tissue (BAT) in temperature control and energy balance and a critical role in the regulation of body weight. Here, we obtained samples of epicardial adipose tissue (EAT)... Read More about Gene pathway development in human epicardial adipose tissue during early life.

The study of progesterone action in human myometrial explants (2016)
Journal Article

Study hypothesis: Myometrial explants represent a superior model compared with cell culture models for the study of human myometrial progesterone (P4) signalling in parturition. Study finding: Gene expression analysis showed myometrial explants clos... Read More about The study of progesterone action in human myometrial explants.

The small molecule hyperphyllin enhances leaf formation rate and mimics shoot meristem integrity defects associated with AMP1 deficiency (2016)
Journal Article

ALTERED MERISTEM PROGRAM1 (AMP1) is a member of the M28 family of carboxypeptidases with a pivotal role in plant development and stress adaptation. Its most prominent mutant defect is a unique hypertrophic shoot phenotype combining a strongly increas... Read More about The small molecule hyperphyllin enhances leaf formation rate and mimics shoot meristem integrity defects associated with AMP1 deficiency.

Identification of gene modules associated with low temperatures response in Bambara groundnut by network-based analysis (2016)
Journal Article

Bambara groundnut (Vigna subterranea (L.) Verdc.) is an African legume and is a promising underutilized crop with good seed nutritional values. Low temperature stress in a number of African countries at night, such as Botswana, can effect the growth... Read More about Identification of gene modules associated with low temperatures response in Bambara groundnut by network-based analysis.

Teaching Data Science and Cloud Computing in Low and Middle Income Countries (2015)
Journal Article

Large, publicly available data sets present a challenge and an opportunity for researchers based in Low and Middle Income Countries (LMIC). The challenge for these researchers is how they can make use of such data sets given their poor connectivity a... Read More about Teaching Data Science and Cloud Computing in Low and Middle Income Countries.

The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana (2015)
Journal Article

Background: Plant cell walls are dynamic structures involved in all aspects of plant growth, environmental interactions and defense responses, and are the most abundant renewable source of carbon-containing polymers on the planet. To balance rigidity... Read More about The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana.

Yeast m6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment (2015)
Journal Article

Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the finding of FTO’s (Fat Mass Obesity) N6-methyladenosine (m6 A) deaminase activity, thus suggesting a link between obesity-... Read More about Yeast m6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment.

The allergenicity of 2S albumin nut proteins: uptake and gene regulation in bmDCs (2014)
Journal Article

Molecular Characterization of Adipose Tissue in the African Elephant (Loxodonta africana) (2014)
Journal Article

Adipose tissue (AT) is a dynamic and flexible organ with regulatory roles in physiological functions including metabolism, reproduction and inflammation; secreted adipokines, including leptin, and fatty acids facilitate many of these roles. The Afric... Read More about Molecular Characterization of Adipose Tissue in the African Elephant (Loxodonta africana).

Pigeons: a novel GUI software for analysing and parsing high density heterologous oligonucleotide microarray probe level data (2014)
Journal Article

Genomic DNA-based probe selection by using high density oligonucleotide arrays has recently been applied to heterologous species (Xspecies). With the advent of this new approach, researchers are able to study the genome and transcriptome of a non-mod... Read More about Pigeons: a novel GUI software for analysing and parsing high density heterologous oligonucleotide microarray probe level data.

Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray (2012)
Journal Article

Background Papaya (Carica papaya L.) is a commercially important crop that produces climacteric fruits with a soft and sweet pulp that contain a wide range of health promoting phytochemicals. Despite its importance, little is known about transcrip... Read More about Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray.

Adenosine methylation in Arabidopsis mRNA is associated with the 3? end and reduced levels cause developmental defects (2012)
Journal Article

We previously showed that the N6-methyladenosine (m6A) mRNA methylase is essential during Arabidopsis thaliana embryonic development. We also demonstrated that this modification is present at varying levels in all mature tissues. However, the require... Read More about Adenosine methylation in Arabidopsis mRNA is associated with the 3? end and reduced levels cause developmental defects.

Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes (2011)
Journal Article

Affymetrix GeneChip microarrays are a powerful tool to study global gene expression profiles and have been used on many species. However, no sheep-specific Affymetrix GeneChip is currently available and the bovine array is fairly limited in its cover... Read More about Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes.

Low-intensity microwave irradiation does not substantially alter gene expression in late larval and adult Caenorhabditis elegans. (2009)
Journal Article

Reports that low-intensity microwave radiation induces heat-shock reporter gene expression in the nematode, Caenorhabditis elegans, have recently been reinterpreted as a subtle thermal effect caused by slight heating. This study used a microwave exp... Read More about Low-intensity microwave irradiation does not substantially alter gene expression in late larval and adult Caenorhabditis elegans..