All Outputs (129)

Sleep disturbance and multimorbidity: a cross-sectional and longitudinal study in the Knee Pain and related health in the Community (KPIC) cohort (2025)
Journal Article
Thompson, W., Swain, S., Coupland, C., Rees, F., Courtney, P., Hall, M., Ferguson, E., Walsh, D. A., Valdes, A. M., Morriss, R., Doherty, M., & Zhang, W. (in press). Sleep disturbance and multimorbidity: a cross-sectional and longitudinal study in the Knee Pain and related health in the Community (KPIC) cohort. SLEEP Advances, https://doi.org/10.1093/sleepadvances/zpaf039

Study Objectives
To examine whether there is a temporal association between sleep disturbance and multimorbidity.

Methods
We performed a cross-sectional and longitudinal observational analysis in people aged 40 years or more, recruited from the... Read More about Sleep disturbance and multimorbidity: a cross-sectional and longitudinal study in the Knee Pain and related health in the Community (KPIC) cohort.

A qualitative exploration into the experience of mindfulness in moderate-severe persistent depression (2025)
Journal Article
Sweeney, T., Nixon, E., Morriss, R., & Callaghan, P. (2025). A qualitative exploration into the experience of mindfulness in moderate-severe persistent depression. PLoS ONE, 20(6), Article e0323294. https://doi.org/10.1371/journal.pone.0323294

Depression is a common and growing mental health problem, with around 5% of the world’s population experiencing an episode of depression during their lifetime. Relapse rates are high, with around half experiencing more than one depressive episode and... Read More about A qualitative exploration into the experience of mindfulness in moderate-severe persistent depression.

Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial (2025)
Journal Article
Nixon, E., Patel, S., Patel, P., Roe, J., Nixon, N., Sweeney, T., Bernard, P., Strauss, C., Craven, M., Malins, S., Goodwin, R., Astill Wright, L., Guo, B., & Morriss, R. (2025). Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial. JMIR Research Protocols, 14, Article e67695. https://doi.org/10.2196/67695

Background:

Recently published guidelines by the National Institute for Health and Care Excellence (NICE) have recommended both mindfulness-based and stress-reduction approaches as effective preventative mental wellbeing interventions for healthca... Read More about Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial.

Facilitators and barriers to participation of patients with treatment resistant depression in a randomised controlled trial of two forms of personalised magnetic resonance imaging targeted transcranial magnetic stimulation (the BRIGhTMIND trial) (2025)
Journal Article
Boutry, C., Webster, L., Thomson, L., Harding, D., Reid, I., Bates, P., Gledhill, J., Mcnaughton, R., Eastham, J., Ooi, J., Willis, A., Marner, S., & Morriss, R. (in press). Facilitators and barriers to participation of patients with treatment resistant depression in a randomised controlled trial of two forms of personalised magnetic resonance imaging targeted transcranial magnetic stimulation (the BRIGhTMIND trial). BMC Psychiatry,

A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT (2025)
Journal Article
Husain, N., Lovell, K., Chew-Graham, C. A., Lunat, F., Bee, P., Pierce, M., Atif, N., Aseem, S., Bhui, K., Bower, P., Brugha, T., Chaudhry, N., Ullah, A., Davies, L., Gire, N., Sharma, D., Miah, J., Ahmed, W., Kai, J., Mirza, I., …Morriss, R. (2025). A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT. Health Technology Assessment, 29(6), 1-113. https://doi.org/10.3310/kkds6622

Background: Postnatal depression is more common in British South Asian women than white women in the United Kingdom. Despite empirical evidence suggesting the effectiveness of cognitive–behavioural therapy as a first line of treatment, little evidenc... Read More about A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT.

Impact of young people’s admissions to adult mental health wards in England: a national qualitative study (2025)
Journal Article
Burn, A.-M., Holland, J., Roe, J., Hopkin, E., Wild, L., Fisher, M., Ford, T., Nazir, S., Dubicka, B., James, A., Tuomainen, H., Fung, N., Wagner, A., Morriss, R., & Sayal, K. (2025). Impact of young people’s admissions to adult mental health wards in England: a national qualitative study. BJPsych Open, 11(2), Article e53. https://doi.org/10.1192/bjo.2024.850

Background
Decision-making capacity (DMC) is key to capacity-based mental health laws. In 2017, Norway introduced a lack of DMC as an additional criterion for involuntary care and treatment to strengthen patient autonomy and reduce involuntary care.... Read More about Impact of young people’s admissions to adult mental health wards in England: a national qualitative study.

Opportunities and challenges to delivering a trial for depressive symptoms in primary care during the COVID-19 pandemic: insights from the Alpha-Stim-D randomised controlled trial (2025)
Journal Article
Patel, S., Patel, P., Boutry, C., Guo, B., Butler, D., Higton, F., McNaughton, R., Briley, P. M., Griffiths, C., Nixon, N., Prasad, V., Sayal, K., Smart, D., Zafar, A., Kai, J., & Morriss, R. (2025). Opportunities and challenges to delivering a trial for depressive symptoms in primary care during the COVID-19 pandemic: insights from the Alpha-Stim-D randomised controlled trial. Trials, 26(1), Article 62. https://doi.org/10.1186/s13063-025-08772-3

Background: Randomised controlled trials (RCTs) are widely regarded as the most powerful research design for evidence-based practice. However, recruiting to RCTs can be challenging resulting in heightened costs and delays in research completion and i... Read More about Opportunities and challenges to delivering a trial for depressive symptoms in primary care during the COVID-19 pandemic: insights from the Alpha-Stim-D randomised controlled trial.

Guidelines and practice: antipsychotics prescribing and physical health monitoring in children and young people, a cohort study using primary care data (2025)
Journal Article
Vinogradova, Y., Jack, R. H., Prasad, V., Coupland, C., Morriss, R., & Hollis, C. (2025). Guidelines and practice: antipsychotics prescribing and physical health monitoring in children and young people, a cohort study using primary care data. BMJ Mental Health, 28(1), 1-8. https://doi.org/10.1136/bmjment-2024-301287

Background: Antipsychotic treatments require physical health monitoring (PHM), especially among children and young people (CYP).
Objective: For CYP aged 5-17, to investigate recorded indications for antipsychotics prescribing and first-treatment dur... Read More about Guidelines and practice: antipsychotics prescribing and physical health monitoring in children and young people, a cohort study using primary care data.

Experiences of the COVID-19 pandemic on child and adolescent psychiatric wards: multi-methods investigation (2024)
Journal Article
Holland, J., Da-Silva-Ellimah, M., Roe, J., Morriss, R., & Sayal, K. (2024). Experiences of the COVID-19 pandemic on child and adolescent psychiatric wards: multi-methods investigation. BJPsych Open, 10(6), Article e197. https://doi.org/10.1192/bjo.2024.783

Background
Child and Adolescent Mental Health Services (CAMHS) inpatient beds are unevenly spread throughout England. Where demand outstrips bed availability, young people may be admitted at-distance or to adult psychiatric wards. The COVID-19 pande... Read More about Experiences of the COVID-19 pandemic on child and adolescent psychiatric wards: multi-methods investigation.

Acceptability, tolerability and safety of the BRIGhTMIND trial: Connectivity-guided intermittent theta-burst stimulation versus F3- repetitive transcranial magnetic stimulation for treatment-resistant depression. (2024)
Journal Article
Webster, L., Boutry, C., Thomson, L., Abdelghani, M., Barber, S., Briley, P. M., Kurkar, M., Lankappa, S., McAllister-Williams, R. H., Suazo Di Paola, A., & Morriss, R. (2025). Acceptability, tolerability and safety of the BRIGhTMIND trial: Connectivity-guided intermittent theta-burst stimulation versus F3- repetitive transcranial magnetic stimulation for treatment-resistant depression. Comprehensive Psychiatry, 136, Article 152544. https://doi.org/10.1016/j.comppsych.2024.152544

Background

The BRIGhTMIND study was a double-blind RCT comparing repetitive transcranial magnetic stimulation at a standard simulation site (the “F3” location given by the International 10–20 system, F3-rTMS) versus connectivity-guided intermitten... Read More about Acceptability, tolerability and safety of the BRIGhTMIND trial: Connectivity-guided intermittent theta-burst stimulation versus F3- repetitive transcranial magnetic stimulation for treatment-resistant depression..

Efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women (ROSHNI-2): a multicentre, randomised controlled trial (2024)
Journal Article
Husain, N., Lunat, F., Lovell, K., Miah, J., Chew-Graham, C. A., Bee, P., Waqas, A., Pierce, M., Sharma, D., Atif, N., Aseem, S., Bhui, K., Bower, P., Brugha, T., Chaudhry, N., Ullah, A., Davies, L., Gire, N., Kai, J., Morrison, J., …Morriss, R. (2024). Efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women (ROSHNI-2): a multicentre, randomised controlled trial. Lancet, 404(10461), 1430-1443. https://doi.org/10.1016/s0140-6736%2824%2901612-x

Background: Postnatal depression necessitates timely and effective interventions to mitigate adverse maternal and child outcomes in the short term and over the life course. British south Asian women with depression are often underserved and undertrea... Read More about Efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women (ROSHNI-2): a multicentre, randomised controlled trial.

Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach (2024)
Journal Article
Radford, K., Kettlewell, J., das Nair, R., Morriss, R., Holmes, J., Kellezi, B., Timmons, S., Jones, T., Tressider, H., Andrews, I., Bridger, K., Patel, P., Lindley, R., De Dios Perez, B., Statham, A., Jones, T., Hoffman, K., James, M., Kendrick, D., & ROWTATE study team. (2024). Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach. BMJ Open, 14(10), Article e085724. https://doi.org/10.1136/bmjopen-2024-085724

Objectives: Major trauma centres save lives but rehabilitation to support return-to-work (RTW) is lacking. This paper describes development of a vocational rehabilitation intervention (the ROWTATE intervention) to support RTW following traumatic inju... Read More about Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach.

Early vocational rehabilitation and psychological support for trauma patients to improve return to work (the ROWTATE trial): study protocol for an individually randomised controlled multicentre pragmatic trial (2024)
Journal Article
Kendrick, D., Lindley, R., Blackburn, L., Roadevin, C., Thompson, E., Andrews, I., Anwar, F., Brooks, A., Carlton, E., Crouch, R., Day, F., Fallon, S., Farrin, A., Graham, L., Hoffman, K., Howell, R., Holmes, J., James, M., Jones, T., Kellezi, B., …Radford, K. (2024). Early vocational rehabilitation and psychological support for trauma patients to improve return to work (the ROWTATE trial): study protocol for an individually randomised controlled multicentre pragmatic trial. Trials, 25(1), Article 439. https://doi.org/10.1186/s13063-024-08183-w

Background
Moderately severe or major trauma (injury severity score (ISS) > 8) is common, often resulting in physical and psychological problems and leading to difficulties in returning to work. Vocational rehabilitation (VR) can improve return to w... Read More about Early vocational rehabilitation and psychological support for trauma patients to improve return to work (the ROWTATE trial): study protocol for an individually randomised controlled multicentre pragmatic trial.

Trajectories of improvement with repetitive transcranial magnetic stimulation for treatment-resistant major depression in the BRIGhTMIND trial (2024)
Journal Article
Briley, P., Webster, L., Lankappa, S., Pszczolkowski, S., H. McAllister-Williams, R., Liddle, P., Auer, D., & Morriss, R. (2024). Trajectories of improvement with repetitive transcranial magnetic stimulation for treatment-resistant major depression in the BRIGhTMIND trial. npj Mental Health Research, 3, Article 32. https://doi.org/10.1038/s44184-024-00077-8

Repetitive transcranial magnetic stimulation (rTMS) is an established non-invasive brain stimulation treatment for major depressive disorder, but there is marked inter-individual variability in response. Using latent class growth analysis with sessio... Read More about Trajectories of improvement with repetitive transcranial magnetic stimulation for treatment-resistant major depression in the BRIGhTMIND trial.

Magnetic resonance imaging connectivity features associated with response to transcranial magnetic stimulation in major depressive disorder (2024)
Journal Article
Briley, P., Webster, L., Boutry, C., Oh, H., Auer, D., Liddle, P., & Morriss, R. (2024). Magnetic resonance imaging connectivity features associated with response to transcranial magnetic stimulation in major depressive disorder. Psychiatry Research: Neuroimaging, 342, Article 111846. https://doi.org/10.1016/j.pscychresns.2024.111846

Transcranial magnetic stimulation (TMS) is an FDA-approved neuromodulation treatment for major depressive disorder (MDD), thought to work by altering dysfunctional brain connectivity pathways, or by indirectly modulating the activity of subcortical b... Read More about Magnetic resonance imaging connectivity features associated with response to transcranial magnetic stimulation in major depressive disorder.

When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial) (2024)
Journal Article
Brown, S., Ploeger, C., Petersen, J. J., Guo, B., Beckenstrom, A. C., Petersen, J. J., Beckenstrom, A. C., Dawson, G. R., Browning, M., Dawson, G. R., Deckert, J., Dourish, C. T., Dias, R., Dourish, C. T., Gorwood, P., Kingslake, J., Menke, A., Sola, V. P., Reif, A., Ruhe, H., …Morriss, R. (2024). When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial). Comprehensive Psychiatry, 132, Article 152467. https://doi.org/10.1016/j.comppsych.2024.152467

Background

A RCT of a novel intervention to detect antidepressant medication response (the PReDicT Test) took place in five European countries, accompanied by a nested study of its acceptability and implementation presented here. The RCT results i... Read More about When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial).

Impact of the COVID-19 pandemic on hospital episodes for falls and fractures associated with new-onset disability and frailty in England: a national cohort study (2024)
Journal Article
Thomas, S., Littleboy, K., Foubert, J., Nafilyan, V., Bannister, N., Routen, A., Morriss, R., Khunti, K., Armstrong, N., Gray, L. J., & Gordon, A. L. (2024). Impact of the COVID-19 pandemic on hospital episodes for falls and fractures associated with new-onset disability and frailty in England: a national cohort study. Age and Ageing, 53(4), Article afae071. https://doi.org/10.1093/ageing/afae071

Background: Older people with frailty are at risk of harm from immobility or isolation, yet data about how COVID-19 lockdowns affected them are limited. Falls and fractures are easily measurable adverse outcomes correlated with frailty. We investigat... Read More about Impact of the COVID-19 pandemic on hospital episodes for falls and fractures associated with new-onset disability and frailty in England: a national cohort study.

Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences (2024)
Journal Article
Patel, P., Brown, S., Guo, B., Holmes, E. A., Iyadurai, L., Kingslake, J., Highfield, J., & Morriss, R. (2024). Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences. JMIR Formative Research, 8(1), Article e47458. https://doi.org/10.2196/47458

Background: Many intensive care unit (ICU) staff experience intrusive memories following work-related traumatic events, which can lead to long-term mental health outcomes and impact work functioning. There is a need for interventions that target intr... Read More about Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences.

Peer mentoring for people with acquired brain injury – a systematic review (2024)
Journal Article
De Dios Perez, B., Morris, R. P., Craven, K., & Radford, K. A. (2024). Peer mentoring for people with acquired brain injury – a systematic review. Brain Injury, 38(4), 316-329. https://doi.org/10.1080/02699052.2024.2310779

Introduction: Over 100 million people worldwide live with disabilities resulting from an acquired brain injury (ABI). ABI survivors experience cognitive and physical problems and require support to resume an active life. They can benefit from support... Read More about Peer mentoring for people with acquired brain injury – a systematic review.

Experiences and impact of psychiatric inpatient admissions far away from home: a qualitative study with young people, parents/carers and healthcare professionals (2024)
Journal Article
Roe, J., Holland, J., Burn, A.-M., Hopkin, E., Wild, L., Fisher, M., Nazir, S., Ford, T., Dubicka, B., James, A., Tuomainen, H., Fung, N., Horton, K., Wagner, A. P., Morriss, R., & Sayal, K. (2024). Experiences and impact of psychiatric inpatient admissions far away from home: a qualitative study with young people, parents/carers and healthcare professionals. BMJ Mental Health, 27(1), Article e300991. https://doi.org/10.1136/bmjment-2024-300991

Background: There are significant clinical, policy and societal concerns about the impact on young people (YP), from admission to psychiatric wards far from home. However, research evidence is scarce.
Aims: To investigate the impact of at-distance... Read More about Experiences and impact of psychiatric inpatient admissions far away from home: a qualitative study with young people, parents/carers and healthcare professionals.