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Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21 (2023)
Preprint / Working Paper
Zachariah, A., Krishnankutty, S. P., Manazhi, J., Omanakuttan, V., Santosh, S., Blanchard, A. M., & Tarlinton, R. E. (2023). Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21

Spill over of SARs-CoV-2 into a variety of wild and domestic animals has been an ongoing feature of the human pandemic. The establishment of a new reservoir in white tailed deer in North America and increasing divergence of the viruses circulating in... Read More about Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21.

Synthesis of discussions of the Second Koala Retrovirus Workshop, 2021 (2023)
Journal Article
Greenwood, A. D., Alquezar-Planas, D. E., McKay, P. A., Mulot, B., Pye, G. W., Robbins, A., Singleton, C. L., Tarlinton, R. E., & Higgins, D. P. (2023). Synthesis of discussions of the Second Koala Retrovirus Workshop, 2021. Technical Reports of the Australian Museum (online), 38, 53-82. https://doi.org/10.3853/j.1835-4211.38.2023.1842

This document represents a synthesis of discussions held online at the Second Koala Retrovirus Workshop in 2021. The three days of discussions were based on workshop presentations and comprise: KoRV foundational science (Day 1); applied management of... Read More about Synthesis of discussions of the Second Koala Retrovirus Workshop, 2021.

An overview of koala retrovirus epidemiology in Australia (2023)
Journal Article
Tarlinton, R. E. (2023). An overview of koala retrovirus epidemiology in Australia. Technical Reports of the Australian Museum (online), 38, 3-6. https://doi.org/10.3853/j.1835-4211.38.2023.1831

Koala retrovirus (KoRV) epidemiology varies across koala (Phascolarctos cinereus) populations with distinct differences in viral prevalence, sequence diversity, and disease impact. Curiously the more genetically restricted southern populations are le... Read More about An overview of koala retrovirus epidemiology in Australia.

Sarbecoviruses of British horseshoe bats; sequence variation and epidemiology (2023)
Journal Article
Apaa, T., Withers, A. J., Staley, C., Blanchard, A., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W. R., Loose, M., Mathews, F., & Tarlinton, R. (2023). Sarbecoviruses of British horseshoe bats; sequence variation and epidemiology. Journal of General Virology, 104(6), https://doi.org/10.1099/jgv.0.001859

Horseshoe bats are the natural hosts of the Sarbecovirus subgenus that includes SARS-CoV and SARS-CoV- 2. Despite the devastating impact of the COVID-19 pandemic, there is still little known about the underlying epidemiology and virology of sarbecovi... Read More about Sarbecoviruses of British horseshoe bats; sequence variation and epidemiology.

Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology (2023)
Journal Article
Apaa, T., Withers, A. J., Staley, C. E., Blanchard, A. M., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W. R., Loose, M., Mathews, F., & Tarlinton, R. E. (2023). Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology. Journal of General Virology, 104(6), Article 001859. https://doi.org/10.1101/2023.02.14.528476

Horseshoe bats are the natural hosts of the Sarbecovirus subgenus that includes SARS-CoV and SARS-CoV- 2. Despite the devastating impact of the COVID-19 pandemic, there is still little known about the underlying epidemiology and virology of sarbecovi... Read More about Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology.

UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI) (2023)
Preprint / Working Paper
McClaughlin, E., Elliott, S., Jewitt, S., Smallman-Raynor, M., Dunham, S., Parnell, T., Clark, M., & Tarlinton, R. UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI)

The scale of the current outbreak of highly pathogenic avian influenza (HPAI) due to the A/H5N1 virus in the United Kingdom is unprecedented. In addition to its economic impact on the commercial poultry sector, the disease has devastated wild bird co... Read More about UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI).

Associations between small ruminant lentivirus infection and total milk yield and somatic cell count in a dairy sheep flock (2023)
Journal Article
Davies, P., Jones, S., Dunham, S., & Tarlinton, R. E. (2023). Associations between small ruminant lentivirus infection and total milk yield and somatic cell count in a dairy sheep flock. Veterinary Record, 192(11), Article e2731. https://doi.org/10.1002/vetr.2731

Background
Small ruminant lentiviruses (SRLVs) are lentiviruses of sheep and goats, formerly known as maedi–visna (MV) in sheep and caprine encephalitis and arthritis in goats. In sheep, SRLVs commonly cause progressive pneumonia, wasting and indura... Read More about Associations between small ruminant lentivirus infection and total milk yield and somatic cell count in a dairy sheep flock.

Genome Reference Assembly for Bottlenecked Southern Australian Koalas (2022)
Journal Article
Blanchard, A. M., Emes, R. D., Greenwood, A. D., Holmes, N., Loose, M. W., McEwen, G. K., Meers, J., Speight, N., & Tarlinton, R. E. (2023). Genome Reference Assembly for Bottlenecked Southern Australian Koalas. Genome Biology and Evolution, 15(1), Article evac176. https://doi.org/10.1093/gbe/evac176

Koala populations show marked differences in inbreeding levels and in the presence or absence of the endogenous Koala retrovirus (KoRV). These genetic differences among populations may lead to severe disease impacts threatening koala population viabi... Read More about Genome Reference Assembly for Bottlenecked Southern Australian Koalas.

Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution (2022)
Preprint / Working Paper
Tarlinton, R. E., Sarker, N., Fabijan, J., Dottorini, T., Woolford, L., Meers, J., Simmons, G., Owen, H., Seddon, J., Hemmatzedah, F., Trott, D., Speight, N., & Emes, R. (2022). Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution

Koala retrovirus (KoRV) is unique amongst endogenous (inherited) retroviruses in that its incorporation to the host genome is still active, providing an opportunity to study what drives this fundamental process in vertebrate genome evolution. Animals... Read More about Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution.

Differential and defective transcription of koala retrovirus indicates the complexity of host and virus evolution (2022)
Journal Article
Tarlinton, R. E., Legione, A. R., Sarker, N., Fabijan, J., Meers, J., McMichael, L., Simmons, G., Owen, H., Seddon, J. .., Dick, G., Ryder, J. S., Hemmatzedah, F., Trott, D. J., Speight, N., Holmes, N., Loose, M., & Emes, R. D. (2022). Differential and defective transcription of koala retrovirus indicates the complexity of host and virus evolution. Journal of General Virology, 103(6), Article 001749. https://doi.org/10.1099/jgv.0.001749

Koala retrovirus (KoRV) is unique amongst endogenous (inherited) retroviruses in that its incorporation to the host genome is still active, providing an opportunity to study what drives this fundamental process in vertebrate genome evolution. Animals... Read More about Differential and defective transcription of koala retrovirus indicates the complexity of host and virus evolution.

Failure to detect Schmallenberg virus RNA in ram semen in the UK (2016–2018) (2022)
Journal Article
Curwen, A., Jones, S., Stayley, C., Eden, L., McKay, H., Davies, P., Lovatt, F., Dunham, S., & Tarlinton, R. (2022). Failure to detect Schmallenberg virus RNA in ram semen in the UK (2016–2018). Veterinary Record Open, 9(1), Article e39. https://doi.org/10.1002/vro2.39

Background
Schmallenberg virus is a midge borne arbovirus that first emerged in the European ruminant population in 2011 and has since settled to an endemic pattern of disease The impacts of trade restrictions on genetic products (semen, embryos) fr... Read More about Failure to detect Schmallenberg virus RNA in ram semen in the UK (2016–2018).

Clearance of Maedi-visna infection in a longitudinal study of naturally infected rams is associated with homozygosity for the TMEM154 resistance allele (2022)
Journal Article
Jones, S., McKay, H., Eden, L., Bollard, N., Dunham, S., Davies, P., & Tarlinton, R. (2022). Clearance of Maedi-visna infection in a longitudinal study of naturally infected rams is associated with homozygosity for the TMEM154 resistance allele. Journal of Medical Microbiology, 71(2), Article 001506. https://doi.org/10.1099/jmm.0.001506

Maedi-visna (MV) is a lentiviral disease of sheep responsible for severe production losses in affected flocks. There are no vaccination or treatment options with control reliant on test and cull strategies. The most common diagnostic methods used at... Read More about Clearance of Maedi-visna infection in a longitudinal study of naturally infected rams is associated with homozygosity for the TMEM154 resistance allele.

Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica (2022)
Journal Article
Shakirova, V., Khaertynova, I., Markelova, M., Tarlinton, R., Behnke, J., Martynova, E., Garanina, E., Rizvanov, A., & Khaiboullina, S. (2022). Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica. BioMed Research International, 2022, Article 4685288. https://doi.org/10.1155/2022/4685288

Nephropathia epidemica (NE) is a zoonotic disease caused by hantaviruses transmitted from rodents, endemic in the Republic of Tatarstan, Russia. The disease presents clinically with mild, moderate, and severe forms, and time-dependent febrile, oligur... Read More about Serum Cytokine Alterations Associated with Age of Patients with Nephropathia Epidemica.

Retroviral integrations contribute to elevated host cancer rates during germline invasion (2021)
Journal Article
McEwen, G. K., Alquezar-Planas, D. E., Dayaram, A., Gillett, A., Tarlinton, R., Mongan, N., Chappell, K. J., Henning, J., Tan, M., Timms, P., Young, P. R., Roca, A. L., & Greenwood, A. D. (2021). Retroviral integrations contribute to elevated host cancer rates during germline invasion. Nature Communications, 12(1), https://doi.org/10.1038/s41467-021-21612-7

© 2021, The Author(s). Repeated retroviral infections of vertebrate germlines have made endogenous retroviruses ubiquitous features of mammalian genomes. However, millions of years of evolution obscure many of the immediate repercussions of retrovira... Read More about Retroviral integrations contribute to elevated host cancer rates during germline invasion.

Transcriptomic and genomic variants between koala populations reveals underlying genetic components to disorders in a bottlenecked population (2021)
Journal Article
Tarlinton, R. E., Fabijan, J., Hemmatzadeh, F., Meers, J., Owen, H., Sarker, N., Seddon, J. M., Simmons, G., Speight, N., Trott, D. J., Woolford, L., & Emes, R. D. (2021). Transcriptomic and genomic variants between koala populations reveals underlying genetic components to disorders in a bottlenecked population. Conservation Genetics, https://doi.org/10.1007/s10592-021-01340-7

© 2021, The Author(s). Historical hunting pressures on koalas in the southern part of their range in Australia have led to a marked genetic bottleneck when compared with their northern counterparts. There are a range of suspected genetic disorders su... Read More about Transcriptomic and genomic variants between koala populations reveals underlying genetic components to disorders in a bottlenecked population.

Role of Viruses in the Pathogenesis of Multiple Sclerosis (2020)
Journal Article
Tarlinton, R. E., Martynova, E., Rizvanov, A., Khaiboullina, S., & Verma, S. (2020). Role of Viruses in the Pathogenesis of Multiple Sclerosis. Viruses, 12(6), 643. https://doi.org/10.3390/v12060643

Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological cause remains elusive. Multiple triggering factors have been suggested, including environmental, genetic and gender components. However, underlying infectious... Read More about Role of Viruses in the Pathogenesis of Multiple Sclerosis.

Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species (2020)
Journal Article
Chappell, J. G., Tsoleridis, T., Onianwa, O., Drake, G., Ashpole, I., Dobbs, P., Edema, W., Kumi-Ansah, F., Bennett, M., Tarlinton, R. E., Ball, J. K., & McClure, C. P. (2020). Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species. Viruses, 12(4), Article 454. https://doi.org/10.3390/v12040454

©2020 by the authors. Licensee MDPI, Basel, Switzerland. Orthohantaviruses are globally distributed viruses, associated with rodents and other small mammals. However, data on the circulation of orthohantaviruses within the UK, particularly the UK-end... Read More about Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species.

Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia (2020)
Journal Article
Fabijan, J., Sarker, N., Speight, N., Owen, H., Meers, J., Simmons, G., Seddon, J., Emes, R. D., Tarlinton, R., Hemmatzadeh, F., Woolford, L., & Trott, D. J. (2020). Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia. Journal of Comparative Pathology, 176, 50-66. https://doi.org/10.1016/j.jcpa.2020.02.003

© 2020 Elsevier Ltd Koala retrovirus (KoRV) infection shows differences in prevalence and load between northern and southern Australian koala populations; however, the effect of this on diseases such as lymphoma and chlamydial disease is unclear. Thi... Read More about Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia.

Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups (2020)
Journal Article
Tarlinton, R., Wang, B., Morandi, E., Gran, B., Khaibullin, T., Martynova, E., Rizvanov, A., & Khaiboullina, S. (2020). Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups. Frontiers in Pharmacology, 10, Article 1645. https://doi.org/10.3389/fphar.2019.01645

Copyright © 2020 Tarlinton, Wang, Morandi, Gran, Khaiboullin, Martynova, Rizvanov and Khaiboullina. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction... Read More about Differential expression of HERV-W in peripheral blood in multiple sclerosis and healthy patients in two different ethnic groups.