All Outputs (7)

One Year of Gluten Free Diet Impacts Gut Function and Microbiome in Celiac Disease (2024)
Journal Article
Costigan, C., Warren, F., Duncan, A., Hoad, C., Lewis, N., Hill, T., Crooks, C., Morgan, P., Ciacci, C., Iovino, P., Sanders, D., Hildebrand, F., Gowland, P., Spiller, R., & MARCIANI, L. (in press). One Year of Gluten Free Diet Impacts Gut Function and Microbiome in Celiac Disease. Clinical Gastroenterology and Hepatology,

BACKGROUND & AIMS: Currently, the main treatment for celiac disease (CD) is gluten free diet (GFD). This observational cohort study investigated the impact of CD and 1 year of GFD on gut function and microbiome.

METHODS: 36 newly diagnosed pat... Read More about One Year of Gluten Free Diet Impacts Gut Function and Microbiome in Celiac Disease.

Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI (2024)
Journal Article
Thorpe, J. C., Thust, S. C., Gillon, C. H., Rowe, S., Swain, C. E., MacArthur, D. C., Howarth, S. P., Avula, S., Morgan, P. S., & Dineen, R. A. (2024). Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI. Journal of Magnetic Resonance Imaging, https://doi.org/10.1002/jmri.29614

Background: Diffusion-weighted imaging (DWI) is routinely used in brain tumor surgery guided by intraoperative MRI (IoMRI). However, conventional echo planar imaging DWI (EPI-DWI) is susceptible to distortion and artifacts that affect image quality.... Read More about Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI.

Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting (2024)
Journal Article
McCabe, A., Martin, S., Rowe, S., Shah, J., Morgan, P. S., Borys, D., & Panek, R. (2024). Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting. European Radiology Experimental, 8(1), Article 27. https://doi.org/10.1186/s41747-024-00429-1

Background: Tumour hypoxia is a recognised cause of radiotherapy treatment resistance in head and neck squamous cell carcinoma (HNSCC). Current positron emission tomography-based hypoxia imaging techniques are not routinely available in many centres.... Read More about Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting.

A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches (2023)
Journal Article
Warrington, S., Ntata, A., Mougin, O., Campbell, J., Torchi, A., Craig, M., …Sotiropoulos, S. N. (2023). A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches. Imaging Neuroscience, 1(2023), 1-27. https://doi.org/10.1162/imag_a_00042

Despite the huge potential of magnetic resonance imaging (MRI) in mapping and exploring the brain, MRI measures can often be limited in their consistency, reproducibility and accuracy which subsequently restricts their quantifiability. Nuisance nonbi... Read More about A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches.

T1 based oxygen-enhanced MRI in tumours; a scoping review of current research (2023)
Journal Article
McCabe, A., Martin, S., Shah, J., Morgan, P. S., & Panek, R. (2023). T1 based oxygen-enhanced MRI in tumours; a scoping review of current research. British Journal of Radiology, 96(1146), Article 20220624. https://doi.org/10.1259/bjr.20220624

OBJECTIVE: Oxygen-enhanced MRI (OE-MRI) or tissue oxygen-level dependent (TOLD) MRI is an imaging technique under investigation for its ability to quantify and map oxygen distributions within tumours. The aim of this study was to identify and charact... Read More about T1 based oxygen-enhanced MRI in tumours; a scoping review of current research.

Dynamic susceptibility-contrast magnetic resonance imaging with contrast agent leakage correction aids in predicting grade in pediatric brain tumours: a multicenter study (2022)
Journal Article
Withey, S. B., MacPherson, L., Oates, A., Powell, S., Novak, J., Abernethy, L., Pizer, B., Grundy, R., Morgan, P. S., Bailey, S., Mitra, D., Arvanitis, T. N., Auer, D. P., Avula, S., & Peet, A. C. (2022). Dynamic susceptibility-contrast magnetic resonance imaging with contrast agent leakage correction aids in predicting grade in pediatric brain tumours: a multicenter study. Pediatric Radiology, 52(6), 1134-1149. https://doi.org/10.1007/s00247-021-05266-7

Background: Relative cerebral blood volume (rCBV) measured using dynamic susceptibility-contrast MRI can differentiate between low- and high-grade pediatric brain tumors. Multicenter studies are required for translation into clinical practice.

Ob... Read More about Dynamic susceptibility-contrast magnetic resonance imaging with contrast agent leakage correction aids in predicting grade in pediatric brain tumours: a multicenter study.

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients (2021)
Journal Article
Izquierdo, E., Proszek, P., Pericoli, G., Temelso, S., Clarke, M., Carvalho, D. M., …Jones, C. (2021). Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients. Neuro-Oncology Advances, 3(1), Article vdab013. https://doi.org/10.1093/noajnl/vdab013

Background
The use of liquid biopsy is of potential high importance for children with high grade (HGG) and diffuse midline gliomas (DMG), particularly where surgical procedures are limited, and invasive biopsy sampling not without risk. To date, how... Read More about Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients.