All Outputs (7)

Prognostication and contemporary management of clinically isolated syndrome (2020)
Journal Article
Allen, C. M., Mowry, E., Tintore, M., & Evangelou, N. (2021). Prognostication and contemporary management of clinically isolated syndrome. Journal of Neurology, Neurosurgery and Psychiatry, 92(4), 391-397. https://doi.org/10.1136/jnnp-2020-323087

Clinically isolated syndrome (CIS) patients present with a single attack of inflammatory demyelination of the central nervous system. Recent advances in multiple sclerosis (MS) diagnostic criteria have expanded the number of CIS patients eligible for... Read More about Prognostication and contemporary management of clinically isolated syndrome.

Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis (2020)
Journal Article
Meng, D., Welton, T., Elsarraj, A., Morgan, P. S., das Nair, R., Constantinescu, C. S., Evangelou, N., Auer, D. P., & Dineen, R. A. (2020). Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis. Human Brain Mapping, 42(2), 495-509. https://doi.org/10.1002/hbm.25239

Three decades ago a series of parallel circuits were described involving the frontal cortex and deep grey matter structures, with putative roles in control of motor and oculomotor function, cognition, behaviour and emotion. The circuit comprising the... Read More about Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis.

Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners (2020)
Journal Article
Smith, L., Elwick, H., Mhizha-Murira, J., Topcu, G., Bale, C., Evangelou, N., Timmons, S., Leighton, P., & Das Nair, R. (2021). Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners. Multiple Sclerosis and Related Disorders, 49, Article 102563. https://doi.org/10.1016/j.msard.2020.102563

Background: Cognitive problems are a common and debilitating symptom of multiple sclerosis (MS). Screening and treatment for cognitive problems are recommended, however these are not routinely delivered in UK clinics.

We collected and synthesised... Read More about Developing a clinical pathway to identify and manage cognitive problems in Multiple Sclerosis: Qualitative findings from patients, family members, charity volunteers, clinicians and healthcare commissioners.

Psychosocial adjustment to multiple sclerosis diagnosis: A meta-review of systematic reviews (2020)
Journal Article
Topcu, G., Griffiths, H., Bale, C., Trigg, E., Clarke, S., Potter, K.-J., Mhizha-Murira, J. R., Drummond, A., Evangelou, N., Fitzsimmons, D., & das Nair, R. (2020). Psychosocial adjustment to multiple sclerosis diagnosis: A meta-review of systematic reviews. Clinical Psychology Review, 82, Article 101923. https://doi.org/10.1016/j.cpr.2020.101923

This meta-review aimed to synthesise evidence on psychosocial adjustment to multiple sclerosis, to identify available treatment models and services for recently diagnosed individuals, and to explore their effectiveness. MEDLINE, CINAHL, EMBASE, PsycI... Read More about Psychosocial adjustment to multiple sclerosis diagnosis: A meta-review of systematic reviews.

Self-diagnosed COVID-19 in people with multiple sclerosis: a community-based cohort of the UK MS Register (2020)
Journal Article
Evangelou, N., Garjani, A., Das Nair, R., Hunter, R., Tuite-Dalton, K., Craig, E., Rodgers, W., Coles, A., Dobson, R., Duddy, M., Ford, D., Hughes, S., Pearson, O., Middleton, L., Rog, D., Tallantyre, E., Friede, T., Middleton, R., & Nicholas, R. (2021). Self-diagnosed COVID-19 in people with multiple sclerosis: a community-based cohort of the UK MS Register. Journal of Neurology, Neurosurgery and Psychiatry, 92(1), 107-109. https://doi.org/10.1136/jnnp-2020-324449

Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial (2020)
Journal Article
Tanasescu, R., Tench, C. R., Constantinescu, C. S., Telford, G., Singh, S., Frakich, N., Onion, D., Auer, D. P., Gran, B., Evangelou, N., Falah, Y., Ranshaw, C., Cantacessi, C., Jenkins, T. P., & Pritchard, D. I. (2020). Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial. JAMA Neurology, 77(9), 1089-1098. https://doi.org/10.1001/jamaneurol.2020.1118

© 2020 American Medical Association. All rights reserved. Importance: Studies suggest gut worms induce immune responses that can protect against multiple sclerosis (MS). To our knowledge, there are no controlled treatment trials with helminth in MS.... Read More about Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial.

Self-help Acceptance and Commitment Therapy for Carers of People with Multiple Sclerosis: A Feasibility Randomised Controlled Trial (2020)
Journal Article
Potter, K.-J., Golijana‑Moghaddam, N., Evangelou, N., Mhizha-Murira, J., & Nair, R. (2021). Self-help Acceptance and Commitment Therapy for Carers of People with Multiple Sclerosis: A Feasibility Randomised Controlled Trial. Journal of Clinical Psychology in Medical Settings, 28, 279-294. https://doi.org/10.1007/s10880-020-09711-x

Introduction:

Acceptance and Commitment Therapy (ACT) is an established psychological therapy, but its effectiveness for carers of people with Multiple Sclerosis experiencing carer-related strain has not been established. This study assessed the... Read More about Self-help Acceptance and Commitment Therapy for Carers of People with Multiple Sclerosis: A Feasibility Randomised Controlled Trial.