All Outputs (7)

Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms (2020)
Journal Article
Viacava, K., Meibom, K. L., Ortega, D., Dyer, S., Gelb, A., Falquet, L., …Bernier-Latmani, R. (2020). Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms. Environmental Science and Technology, 54(22), 14343-14351. https://doi.org/10.1021/acs.est.0c03908

© 2020 American Chemical Society. Microbially-mediated methylation of arsenic (As) plays an important role in the As biogeochemical cycle, particularly in rice paddy soils where methylated As, generated microbially, is translocated into rice grains.... Read More about Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms.

Synthetic biology on acetogenic bacteria for highly efficient conversion of c1 gases to biochemicals (2020)
Journal Article
Jin, S., Bae, J., Song, Y., Pearcy, N., Shin, J., Kang, S., …Cho, B. K. (2020). Synthetic biology on acetogenic bacteria for highly efficient conversion of c1 gases to biochemicals. International Journal of Molecular Sciences, 21(20), Article 7639. https://doi.org/10.3390/ijms21207639

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Synthesis gas, which is mainly produced from fossil fuels or biomass gasification, consists of C1 gases such as carbon monoxide, carbon dioxide, and methane as well as hydrogen. Acetogenic bac... Read More about Synthetic biology on acetogenic bacteria for highly efficient conversion of c1 gases to biochemicals.

The glucosyltransferase activity of C. difficile toxin b is required for disease pathogenesis (2020)
Journal Article
Bilverstone, T. W., Garland, M., Cave, R. J., Kelly, M. L., Tholen, M., Bouley, D. M., …Melnyk, R. A. (2020). The glucosyltransferase activity of C. difficile toxin b is required for disease pathogenesis. PLoS Pathogens, 16(9), Article e1008852. https://doi.org/10.1371/journal.ppat.1008852

© 2020 Bilverstone et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ar... Read More about The glucosyltransferase activity of C. difficile toxin b is required for disease pathogenesis.

Using singular perturbation theory to determine kinetic parameters in a non-standard coupled enzyme assay (2020)
Journal Article
Dalwadi, M. P., Orol, D., Walter, F., Minton, N. P., King, J. R., & Kovács, K. (2020). Using singular perturbation theory to determine kinetic parameters in a non-standard coupled enzyme assay. Journal of Mathematical Biology, 81(2), 649-690. https://doi.org/10.1007/s00285-020-01524-8

We investigate how to characterize the kinetic parameters of an aminotransaminase using a non-standard coupled (or auxiliary) enzyme assay, where the peculiarity arises for two reasons. First, one of the products of the auxiliary enzyme is a substrat... Read More about Using singular perturbation theory to determine kinetic parameters in a non-standard coupled enzyme assay.

A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2 (2020)
Journal Article
Bommareddy, R. R., Wang, Y., Pearcy, N., Hayes, M., Lester, E., Minton, N. P., & Conradie, A. V. (2020). A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2. iScience, 23(6), Article 101218. https://doi.org/10.1016/j.isci.2020.101218

© 2020 The Author(s) The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through techno... Read More about A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2.

A gold standard, CRISPR/Cas9-based complementation strategy reliant on 24 nucleotide bookmark sequences (2020)
Journal Article
Seys, F. M., Rowe, P., Bolt, E. L., Humphreys, C. M., & Minton, N. P. (2020). A gold standard, CRISPR/Cas9-based complementation strategy reliant on 24 nucleotide bookmark sequences. Genes, 11(4), Article 458. https://doi.org/10.3390/genes11040458

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Phenotypic complementation of gene knockouts is an essential step in establishing function. Here, we describe a simple strategy for ‘gold standard’ complementation in which the mutant allele i... Read More about A gold standard, CRISPR/Cas9-based complementation strategy reliant on 24 nucleotide bookmark sequences.

A genome-wide approach for identification and characterisation of metabolite-inducible systems (2020)
Journal Article
Hanko, E. K. R., Paiva, A. C., Jonczyk, M., Abbott, M., Minton, N. P., & Malys, N. (2020). A genome-wide approach for identification and characterisation of metabolite-inducible systems. Nature Communications, 11(1), Article 1213. https://doi.org/10.1038/s41467-020-14941-6

© 2020, The Author(s). Inducible gene expression systems are vital tools for the advancement of synthetic biology. Their application as genetically encoded biosensors has the potential to contribute to diagnostics and to revolutionise the field of mi... Read More about A genome-wide approach for identification and characterisation of metabolite-inducible systems.