All Outputs (22)

Trifluoromethylation of Allylsilanes under Photoredox Catalysis (2013)
Journal Article
Mizuta, S., Engle, K. M., Verhoog, S., Galicia-López, O., O’Duill, M., Médebielle, M., Wheelhouse, K., Rassias, G., Thompson, A. L., & Gouverneur, V. (2013). Trifluoromethylation of Allylsilanes under Photoredox Catalysis. Organic Letters, 15(6), 1250–1253. https://doi.org/10.1021/ol400184t

A new catalytic method to access allylic secondary CF3 products is described. These reactions use the visible light excited Ru(bpy)3Cl2·6H2O catalyst and the Togni or Umemoto reagent as the CF3 source. The photoredox catalytic manifold delivers enant... Read More about Trifluoromethylation of Allylsilanes under Photoredox Catalysis.

Catalytic Hydrotrifluoromethylation of Unactivated Alkenes (2013)
Journal Article
Mizuta, S., Verhoog, S., Engle, K. M., Khotavivattana, T., O’Duill, M., Wheelhouse, K., Rassias, G., Médebielle, M., & Gouverneur, V. (2013). Catalytic Hydrotrifluoromethylation of Unactivated Alkenes. Journal of the American Chemical Society, 135(7), 2505–2508. https://doi.org/10.1021/ja401022x

A visible-light-mediated hydrotrifluoromethylation of unactivated alkenes that uses the Umemoto reagent as the CF3 source and MeOH as the reductant is disclosed. This effective transformation operates at room temperature in the presence of 5 mol % Ru... Read More about Catalytic Hydrotrifluoromethylation of Unactivated Alkenes.