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All Outputs (95)

A lightweight magnetically shielded room with active shielding (2022)
Journal Article
Holmes, N., Rea, M., Chalmers, J., Leggett, J., Edwards, L. J., Nell, P., …Bowtell, R. (2022). A lightweight magnetically shielded room with active shielding. Scientific Reports, 12, Article 13561. https://doi.org/10.1038/s41598-022-17346-1

Magnetically shielded rooms (MSRs) use multiple layers of materials such as MuMetal to screen external magnetic fields that would otherwise interfere with high precision magnetic field measurements such as magnetoencephalography (MEG). Optically pump... Read More about A lightweight magnetically shielded room with active shielding.

Predicting time-resolved electrophysiological brain networks from structural eigenmodes (2022)
Journal Article
Tewarie, P., Prasse, B., Meier, J., Mandke, K., Warrington, S., Stam, C. J., …Hillebrand, A. (2022). Predicting time-resolved electrophysiological brain networks from structural eigenmodes. Human Brain Mapping, https://doi.org/10.1002/hbm.25967

How temporal modulations in functional interactions are shaped by the underlying anatomical connections remains an open question. Here, we analyse the role of structural eigenmodes, in the formation and dissolution of temporally evolving functional b... Read More about Predicting time-resolved electrophysiological brain networks from structural eigenmodes.

On-Scalp Optically Pumped Magnetometers versus Cryogenic Magnetoencephalography for Diagnostic Evaluation of Epilepsy in School-aged Children (2022)
Journal Article
Feys, O., Corvilain, P., Aeby, A., Sculier, C., Holmes, N., Brookes, M., …De Tiège, X. (2022). On-Scalp Optically Pumped Magnetometers versus Cryogenic Magnetoencephalography for Diagnostic Evaluation of Epilepsy in School-aged Children. Radiology, 304(2), 429-434. https://doi.org/10.1148/radiol.212453

Background Magnetoencephalography (MEG) is an established method used to detect and localize focal interictal epileptiform discharges (IEDs). Current MEG systems house hundreds of cryogenic sensors in a rigid, one-size-fits-all helmet, which results... Read More about On-Scalp Optically Pumped Magnetometers versus Cryogenic Magnetoencephalography for Diagnostic Evaluation of Epilepsy in School-aged Children.

Using OPM-MEG in contrasting magnetic environments (2022)
Journal Article
Hill, R. M., Devasagayam, J., Holmes, N., Boto, E., Shah, V., Osborne, J., …Brookes, M. J. (2022). Using OPM-MEG in contrasting magnetic environments. NeuroImage, 253, Article 119084. https://doi.org/10.1016/j.neuroimage.2022.119084

Magnetoencephalography (MEG) has been revolutionised by optically pumped magnetometers (OPMs). “OPM-MEG” offers higher sensitivity, better spatial resolution, and lower cost than conventional instrumentation based on superconducting quantum interfere... Read More about Using OPM-MEG in contrasting magnetic environments.

Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm (2022)
Journal Article
Packer, M., Hobson, P. J., Davis, A., Holmes, N., Leggett, J., Glover, P., Hardwicke, N. L., Brookes, M. J., Bowtell, R., & Fromhold, T. M. (2022). Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm. Journal of Applied Physics, 131(9), Article 093902. https://doi.org/10.1063/5.0071986

Magnetically sensitive experiments and newly developed quantum technologies with integrated high-permeability magnetic shields require increasing control of their magnetic field environment and reductions in size, weight, power, and cost. However, ma... Read More about Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm.

Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children (2022)
Journal Article
Boto, E., Shah, V., Hill, R. M., Rhodes, N., Osborne, J., Doyle, C., …Brookes, M. J. (2022). Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children. NeuroImage, 252, Article 119027. https://doi.org/10.1016/j.neuroimage.2022.119027

Optically-pumped magnetometers (OPMs) are an established alternative to superconducting sensors for magnetoencephalography (MEG), offering significant advantages including flexibility to accommodate any head size, uniform coverage, free movement duri... Read More about Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children.

The oscillatory effects of rhythmic median nerve stimulation (2022)
Journal Article
Houlgreave, M. S., Morera Maiquez, B., Brookes, M. J., & Jackson, S. R. (2022). The oscillatory effects of rhythmic median nerve stimulation. NeuroImage, 251, Article 118990. https://doi.org/10.1016/j.neuroimage.2022.118990

Entrainment of brain oscillations can be achieved using rhythmic non-invasive brain stimulation, and stimulation of the motor cortex at a frequency associated with sensorimotor inhibition can impair motor responses. Despite the potential for therapeu... Read More about The oscillatory effects of rhythmic median nerve stimulation.

Optimised hybrid shielding and magnetic field control for emerging quantum technologies (2021)
Presentation / Conference Contribution
Hobson, P. J., Packer, M., Holmes, N., Davis, A., Patel, P., Holmes, D., Harrison, R., Chalmers, J., Styles, B., Woolger, D., Sims, D., Brookes, M. J., & Fromhold, T. M. (2021, September). Optimised hybrid shielding and magnetic field control for emerging quantum technologies. Presented at SPIE PHOTONEX, Glasgow, United Kingdom

The accurate control of magnetic fields is a cornerstone of multiple emerging quantum technologies. These technologies often require passive high permeability magnetic shielding and internal active field-generating coils to create their own bespoke m... Read More about Optimised hybrid shielding and magnetic field control for emerging quantum technologies.

Mild traumatic brain injury impairs the coordination of intrinsic and motor-related neural dynamics (2021)
Journal Article
Rier, L., Zamyadi, R., Zhang, J., Emami, Z., Seedat, Z. A., Mocanu, S., …Dunkley, B. T. (2021). Mild traumatic brain injury impairs the coordination of intrinsic and motor-related neural dynamics. NeuroImage: Clinical, 32, Article 102841. https://doi.org/10.1016/j.nicl.2021.102841

Mild traumatic brain injury (mTBI) poses a considerable burden on healthcare systems. Whilst most patients recover quickly, a significant number suffer from sequelae that are not accompanied by measurable structural damage. Understanding the neural u... Read More about Mild traumatic brain injury impairs the coordination of intrinsic and motor-related neural dynamics.

Practical real-time MEG-based neural interfacing with optically pumped magnetometers (2021)
Journal Article
Wittevrongel, B., Holmes, N., Boto, E., Hill, R., Rea, M., Libert, A., …Brookes, M. J. (2021). Practical real-time MEG-based neural interfacing with optically pumped magnetometers. BMC Biology, 19(1), Article 158. https://doi.org/10.1186/s12915-021-01073-6

Background: Brain-computer interfaces decode intentions directly from the human brain with the aim to restore lost functionality, control external devices or augment daily experiences. To combine optimal performance with wide applicability, high-qual... Read More about Practical real-time MEG-based neural interfacing with optically pumped magnetometers.

Magnetic Field Mapping and Correction for Moving OP-MEG (2021)
Journal Article
Mellor, S., Tierney, T. M., O'Neill, G. C., Alexander, N., Seymour, R. A., Holmes, N., …Barnes, G. R. (2022). Magnetic Field Mapping and Correction for Moving OP-MEG. IEEE Transactions on Biomedical Engineering, 69(2), 528-536. https://doi.org/10.1109/TBME.2021.3100770

Background: Optically pumped magnetometers (OPMs) have made moving, wearable magnetoencephalography (MEG) possible. The OPMs typically used for MEG require a low background magnetic field to operate, which is achieved using both passive and active ma... Read More about Magnetic Field Mapping and Correction for Moving OP-MEG.

Precision magnetic field modelling and control for wearable magnetoencephalography (2021)
Journal Article
Rea, M., Holmes, N., Hill, R. M., Boto, E., Leggett, J., Edwards, L. J., …Brookes, M. J. (2021). Precision magnetic field modelling and control for wearable magnetoencephalography. NeuroImage, 241, Article 118401. https://doi.org/10.1016/j.neuroimage.2021.118401

Optically-pumped magnetometers (OPMs) are highly sensitive, compact magnetic field sensors, which offer a viable alternative to cryogenic sensors (superconducting quantum interference devices – SQUIDs) for magnetoencephalography (MEG). With the promi... Read More about Precision magnetic field modelling and control for wearable magnetoencephalography.

Interlayer connectivity reconstruction for multilayer brain networks using phase oscillator models (2021)
Journal Article
Tewarie, P., Prasse, B., Meier, J. M., Byrne, Á., De Domenico, M., Stam, C. J. (., …Van Mieghem, P. (2021). Interlayer connectivity reconstruction for multilayer brain networks using phase oscillator models. New Journal of Physics, 23(6), Article 063065. https://doi.org/10.1088/1367-2630/ac066d

Large-scale neurophysiological networks are often reconstructed from band-pass filtered time series derived from magnetoencephalography (MEG) data. Common practice is to reconstruct these networks separately for different frequency bands and to treat... Read More about Interlayer connectivity reconstruction for multilayer brain networks using phase oscillator models.

Theoretical advantages of a triaxial optically pumped magnetometer magnetoencephalography system (2021)
Journal Article
Brookes, M. J., Boto, E., Rea, M., Shah, V., Osborne, J., Holmes, N., …Bowtell, R. (2021). Theoretical advantages of a triaxial optically pumped magnetometer magnetoencephalography system. NeuroImage, 236, Article 118025. https://doi.org/10.1016/j.neuroimage.2021.118025

The optically pumped magnetometer (OPM) is a viable means to detect magnetic fields generated by human brain activity. Compared to conventional detectors (superconducting quantum interference devices) OPMs are small, lightweight, flexible, and operat... Read More about Theoretical advantages of a triaxial optically pumped magnetometer magnetoencephalography system.

Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study (2021)
Journal Article
Sebastian, S., Walker, G. J., Kennedy, N. A., Conley, T. E., Patel, K. V., Subramanian, S., …Zafar, M. (2021). Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study. Lancet Gastroenterology and Hepatology, 6(4), 271-281. https://doi.org/10.1016/s2468-1253%2821%2900016-9

Background
There is a paucity of evidence to support safe and effective management of patients with acute severe ulcerative colitis during the COVID-19 pandemic. We sought to identify alterations to established conventional evidence-based management... Read More about Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study.

Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity (2020)
Journal Article
Gascoyne, L. E., Brookes, M. J., Rathnaiah, M., Zia Ul Haq Katshu, M., Koelewijn, L., Williams, G., …Morris, P. G. (2021). Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity. NeuroImage: Clinical, 29, Article 102524. https://doi.org/10.1016/j.nicl.2020.102524

Magnetoencephalography (MEG) measures magnetic fields generated by synchronised neural current flow and provides direct inference on brain electrophysiology and connectivity, with high spatial and temporal resolution. The movement-related beta decrea... Read More about Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity.

Optimal Inverse Design of Magnetic Field Profiles in a Magnetically Shielded Cylinder (2020)
Journal Article
Packer, M., Hobson, P., Holmes, N., Leggett, J., Glover, P., Brookes, M., …Fromhold, T. (2020). Optimal Inverse Design of Magnetic Field Profiles in a Magnetically Shielded Cylinder. Physical Review Applied, 14(5), Article 054004. https://doi.org/10.1103/PhysRevApplied.14.054004

Magnetic shields that use both active and passive components to enable the generation of a tailored low-field environment are required for many applications in science, engineering, and medical imaging. Until now, accurate field nulling, or field gen... Read More about Optimal Inverse Design of Magnetic Field Profiles in a Magnetically Shielded Cylinder.