All Outputs (9)

Lateral interactions govern self-assembly of the bacterial biofilm matrix protein BslA (2023)
Journal Article
Arnaouteli, S., Bamford, N. C., Brandani, G. B., Morris, R. J., Schor, M., Carrington, J. T., Hobley, L., van Aalten, D. M. F., Stanley-Wall, N. R., & MacPhee, C. E. (2023). Lateral interactions govern self-assembly of the bacterial biofilm matrix protein BslA. Proceedings of the National Academy of Sciences, 120(45), Article e2312022120. https://doi.org/10.1073/pnas.2312022120

The soil bacterium Bacillus subtilis is a model organism to investigate the formation of biofilms, the predominant form of microbial life. The secreted protein BslA self-assembles at the surface of the biofilm to give the B. subtilis biofilm its char... Read More about Lateral interactions govern self-assembly of the bacterial biofilm matrix protein BslA.

Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent (2020)
Journal Article
Storey, D., McNally, A., Åstrand, M., sa-Pessoa Graca Santos, J., Rodriguez-Escudero, I., Elmore, B., Palacios, L., Marshall, H., Hobley, L., Molina, M., Cid, V. J., Salminen, T. A., & Bengoechea, J. A. (2020). Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent. PLoS Pathogens, 16(3), Article e1007969. https://doi.org/10.1371/journal.ppat.1007969

Copyright: © 2020 Storey et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and sou... Read More about Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent.

Dual predation by bacteriophage and bdellovibrio bacteriovorus can eradicate escherichia coli prey in situations where single predation cannot (2020)
Journal Article
Hobley, L., Summers, J. K., Till, R., Milner, D. S., Atterbury, R. J., Stroud, A., Capeness, M. J., Gray, S., Leidenroth, A., Lambert, C., Connerton, I., Twycross, J., Baker, M., Tyson, J., Kreft, J. U., & Sockett, R. E. (2020). Dual predation by bacteriophage and bdellovibrio bacteriovorus can eradicate escherichia coli prey in situations where single predation cannot. Journal of Bacteriology, 202(6), Article e00629-19. https://doi.org/10.1128/JB.00629-19

Copyright © 2020 Hobley et al. Bacteria are preyed upon by diverse microbial predators, including bacteriophage and predatory bacteria, such as Bdellovibrio bacteriovorus. While bacteriophage are used as antimicrobial therapies in Eastern Europe and... Read More about Dual predation by bacteriophage and bdellovibrio bacteriovorus can eradicate escherichia coli prey in situations where single predation cannot.

Nucleotide signaling pathway convergence in a cAMP‐sensing bacterial c‐di‐GMP phosphodiesterase (2019)
Journal Article
Cadby, I. T., Basford, S. M., Nottingham, R., Meek, R., Lowry, R., Lambert, C., Tridgett, M., Till, R., Ahmad, R., Fung, R., Hobley, L., Hughes, W. S., Moynihan, P. J., Sockett, R. E., & Lovering, A. L. (2019). Nucleotide signaling pathway convergence in a cAMP‐sensing bacterial c‐di‐GMP phosphodiesterase. EMBO Journal, 38(17), Article e100772. https://doi.org/10.15252/embj.2018100772

Bacterial usage of the cyclic dinucleotide c-di-GMP is widespread, governing the transition between motile/sessile and unicellular/ multicellular behaviors. There is limited information on c-di-GMP metabolism, particularly on regulatory mechanisms go... Read More about Nucleotide signaling pathway convergence in a cAMP‐sensing bacterial c‐di‐GMP phosphodiesterase.

Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria (2012)
Journal Article
Hobley, L., Lerner, T. R., Williams, L. E., Lambert, C., Till, R., Milner, D. S., Basford, S. M., Capeness, M. J., Fenton, A. K., Atterbury, R. J., Harris, M. A., & Sockett, R. E. (2012). Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria. BMC Genomics, 13(670), https://doi.org/10.1186/1471-2164-13-670

Background:

Evolution equipped Bdellovibrio bacteriovorus predatory bacteria to invade other bacteria, digesting and replicating, sealed within them thus preventing nutrient-sharing with organisms in the surrounding environment. Bdellovibrio were... Read More about Genome analysis of a simultaneously predatory and prey-independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria.

Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in Bdellovibrio bacteriovorus (2012)
Journal Article
Hobley, L., Fung, R. K. Y., Lambert, C., Harris, M. A., Dabh, J. M., King, S. S., Basford, S. M., Uchida, K., Till, R., Ahmad, R., Aizawa, S.-I., Gomelsky, M., & Sockett, R. E. (2012). Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in Bdellovibrio bacteriovorus. PLoS Pathogens, 8(2), Article e1002493. https://doi.org/10.1371/journal.ppat.1002493

Bdellovibrio bacteriovorus is a Delta-proteobacterium that oscillates between free-living growth and predation on Gram-negative bacteria including important pathogens of man, animals and plants. After entering the prey periplasm, killing the prey and... Read More about Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in Bdellovibrio bacteriovorus.

The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth (2011)
Journal Article
Chang, C.-Y., Hobley, L., Till, R., Capeness, M., Kanna, M., Burtt, W., Jagtap, P., Aizawa, S.-I., & Sockett, R. E. (2011). The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth. Microbiology, 157(11), https://doi.org/10.1099/mic.0.052449-0

Bdellovibrio bacteriovorus grows in one of two ways: either (i) predatorily [in a host-dependent (HD) manner], when it invades the periplasm of another Gram-negative bacterium, exporting into the prey co-ordinated waves of soluble enzymes using the p... Read More about The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth.

Effects of orally administered Bdellovibrio bacteriovorus on the well-being and Salmonella colonization of young chicks (2011)
Journal Article
Atterbury, R. J., Hobley, L., Till, R., Lambert, C., Capeness, M. J., Lerner, T. R., Fenton, A. K., Barrow, P., & Sockett, R. E. (2011). Effects of orally administered Bdellovibrio bacteriovorus on the well-being and Salmonella colonization of young chicks. Applied and Environmental Microbiology, 77(16), https://doi.org/10.1128/AEM.00426-11

Bdellovibrio bacteriovorus is a bacterium which preys upon and kills Gram-negative bacteria, including the zoonotic pathogens Escherichia coli and Salmonella. Bdellovibrio has potential as a biocontrol agent, but no reports of it being tested in livi... Read More about Effects of orally administered Bdellovibrio bacteriovorus on the well-being and Salmonella colonization of young chicks.

An inside job: Bdellovibrio bacteriovorus (2008)
Journal Article
Sockett, L., Hobley, L., Fenton, A., Woods, R., Lambert, C., Chang, C. Y., Atterbury, R., Till, R., Whitworth, M., Capeness, M., Fung, R., Ahmad, R., Milner, D., Lerner, T., & King, S. (2008). An inside job: Bdellovibrio bacteriovorus. Microbiology Today, 35(4), 184-187