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Efficacy and safety of statins, ezetimibe and statins-ezetimibe therapies for children and adolescents with heterozygous familial hypercholesterolaemia: Systematic review, pairwise and network meta-analyses of randomised controlled trials (2024)
Journal Article
Llewellyn, A., Simmonds, M., Marshall, D., Harden, M., Woods, B., Humphries, S. E., Ramaswami, U., Priestley-Barnham, L., Fisher, M., Tata, L. J., & Qureshi, N. (2024). Efficacy and safety of statins, ezetimibe and statins-ezetimibe therapies for children and adolescents with heterozygous familial hypercholesterolaemia: Systematic review, pairwise and network meta-analyses of randomised controlled trials. Atherosclerosis, Article 118598. https://doi.org/10.1016/j.atherosclerosis.2024.118598

Background and aims: Statins, ezetimibe and statins-ezetimibe combination therapy are recommended lipid-lowering therapies (LLTs) in children with heterozygous familial hypercholesterolaemia (HeFH). However, their relative effectiveness is not well u... Read More about Efficacy and safety of statins, ezetimibe and statins-ezetimibe therapies for children and adolescents with heterozygous familial hypercholesterolaemia: Systematic review, pairwise and network meta-analyses of randomised controlled trials.

Short-term risk of cardiovascular events in people newly diagnosed with gout (2024)
Journal Article
Cipolletta, E., Nakafero, G., Richette, P., Avery, A. J., Mamas, M. A., Tata, L. J., & Abhishek, A. (2024). Short-term risk of cardiovascular events in people newly diagnosed with gout. Arthritis and Rheumatology, https://doi.org/10.1002/art.42986

Objectives
To investigate the temporal association between first diagnosis of gout and cardiovascular events in the short-term.

Methods
We performed a self-controlled case series analysis and a cohort study using data from linked primary care, h... Read More about Short-term risk of cardiovascular events in people newly diagnosed with gout.

Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data (2024)
Journal Article
CIPOLLETTA, E., Nakafero, G., McCormick, N., Yokose, C., Avery, A., Mamas, M., Choi, H., Tata, L., & Abhishek, A. (in press). Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data. The Lancet Rheumatology,

Background Starting urate-lowering therapy (ULT) may trigger gout flares. Gout flares have been temporally associated with an increased risk of cardiovascular events (CVEs).
Objective To estimate the risk of CVEs among patients with gout initiating... Read More about Cardiovascular events in gout patients starting urate-lowering therapy with or without colchicine for flare prophylaxis: a new-user cohort study using linked primary care, hospitalisation and mortality data.

Patterns and trends of medicinal poisoning substances: a population-based cohort study of injuries in 0-11 year old children from 1998-2018 (2024)
Journal Article
Tyrrell, E. G., Orton, E., Tata, L. J., & Kendrick, D. (2024). Patterns and trends of medicinal poisoning substances: a population-based cohort study of injuries in 0-11 year old children from 1998-2018. Archives of Public Health, 82(1), Article 50. https://doi.org/10.1186/s13690-024-01268-7

Background
There have been sharp increases in antidepressant and opioid prescriptions over the last 10 years, as well as increased over-the-counter medicine availability. However, the impact on childhood medicinal poisonings rates, particularly by s... Read More about Patterns and trends of medicinal poisoning substances: a population-based cohort study of injuries in 0-11 year old children from 1998-2018.

Assessing the value of integrating national longitudinal shopping data into respiratory disease forecasting models (2023)
Journal Article
Dolan, E., Goulding, J., Marshall, H., Smith, G., Long, G., & Tata, L. J. (2023). Assessing the value of integrating national longitudinal shopping data into respiratory disease forecasting models. Nature Communications, 14, Article 7258. https://doi.org/10.1038/s41467-023-42776-4

The COVID-19 pandemic led to unparalleled pressure on healthcare services. Improved healthcare planning in relation to diseases affecting the respiratory system has consequently become a key concern. We investigated the value of integrating sales of... Read More about Assessing the value of integrating national longitudinal shopping data into respiratory disease forecasting models.

Qualitative Investigation of the Novel Use of Shopping Loyalty Card Data in Medical Decision Making (2023)
Book Chapter
Lang, A., Dolan, E., Tata, L., & Goulding, J. (2023). Qualitative Investigation of the Novel Use of Shopping Loyalty Card Data in Medical Decision Making. In M. Melles, A. Albayrak, & R. H. Goossens (Eds.), Convergence: Breaking Down Barriers Between Disciplines: Proceedings of the International Conference on Healthcare Systems Ergonomics and Patient Safety, HEPS2022. Springer. https://doi.org/10.1007/978-3-031-32198-6_11

This paper describes early results of a small qualitative study investigating the potential impact of shopping loyalty card data (SLCD) in the diagnostic pathway for ovarian cancer. There is early evidence that pharmaceutical products such as pain re... Read More about Qualitative Investigation of the Novel Use of Shopping Loyalty Card Data in Medical Decision Making.

Using Shopping Data to Improve the Diagnosis of Ovarian Cancer: Computational Analysis of a Web-Based Survey (2023)
Journal Article
Dolan, E., Goulding, J., Tata, L., & Lang, A. (2023). Using Shopping Data to Improve the Diagnosis of Ovarian Cancer: Computational Analysis of a Web-Based Survey. JMIR Cancer, 9, Article e37141. https://doi.org/10.2196/37141

Background

Shopping data can be analysed using machine learning techniques to study population health. It is unknown if use of such methods can successfully investigate pre-diagnosis purchases linked to self-medication of symptoms of ovarian cance... Read More about Using Shopping Data to Improve the Diagnosis of Ovarian Cancer: Computational Analysis of a Web-Based Survey.

Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout (2022)
Journal Article
Cipolletta, E., Tata, L. J., Nakafero, G., Avery, A. J., Mamas, M. A., & Abhishek, A. (2022). Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout. Journal of the American Medical Association, 328(5), 440-450. https://doi.org/10.1001/jama.2022.11390

Importance: Gout is associated with cardiovascular diseases. The temporal association between gout flares and cardiovascular events has not been investigated. Objective: To investigate whether there is a transient increase in risk of cardiovascular e... Read More about Association between Gout Flare and Subsequent Cardiovascular Events among Patients with Gout.

Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink (2022)
Journal Article
Abhishek, A., Cipolletta, E., Nakafero, G., Avery, A. J., Mamas, M., & Tata, L. J. (2022). Serum urate outcomes of treat-to-target urate lowering treatment: results of a nationwide cohort study from 1997 to the COVID-19 pandemic using data from the Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, 81(12), https://doi.org/10.1136/ard-2022-222668

Has the gout epidemic peaked in the UK? A nationwide cohort study using data from the Clinical Practice Research Datalink, from 1997 to across the COVID-19 pandemic in 2021 (2022)
Journal Article
Abhishek, A., Tata, L. J., Mamas, M., & Avery, A. J. (2022). Has the gout epidemic peaked in the UK? A nationwide cohort study using data from the Clinical Practice Research Datalink, from 1997 to across the COVID-19 pandemic in 2021. Annals of the Rheumatic Diseases, 81(6), 898-899. https://doi.org/10.1136/annrheumdis-2021-221989

Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial (2021)
Journal Article
Morriss, R., Kaylor-Hughes, C., Rawsthorne, M., Coulson, N., Simpson, S., Guo, B., …Williams, L. (2021). Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial. Journal of Medical Internet Research, 23(7), Article e31543. https://doi.org/10.2196/31543

[This corrects the article DOI: 10.2196/23487.].

A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial (2021)
Journal Article
Rawsthorne, M., Tata, L., Williams, L., Morriss, R., Guo, B., Simpson, S., …Moran, P. (2021). A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial. Journal of Medical Internet Research, 23(4), Article e23487. https://doi.org/10.2196/23487

Background: Effective help for depression and anxiety reaches a small proportion of people who might benefit from it. The scale of the problem suggests the need for effective, safe web-based public health services delivered directly to the public. On... Read More about A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial.

Trends in prescribing of nicotine replacement therapy to pregnant women in primary care in England (2021)
Journal Article
Szatkowski, L., Reeves Vaz, L., Fiaschi, L., Tata, L., & Coleman, T. (2021). Trends in prescribing of nicotine replacement therapy to pregnant women in primary care in England. Nicotine and Tobacco Research, 23(9), 1607-1610. https://doi.org/10.1093/ntr/ntab037

Introduction: Smoking during pregnancy remains common and the English National Health Service (NHS) has recently been directed to prioritise providing cessation support for pregnant women. We investigated the impact on prescribing of stop smoking tre... Read More about Trends in prescribing of nicotine replacement therapy to pregnant women in primary care in England.

Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study (2020)
Journal Article
Ahankari, A., Kabra, P., Tata, L., Hayter, M., & Fogarty, A. (2021). Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study. Tropical Medicine and International Health, 26(3), 327-334. https://doi.org/10.1111/tmi.13524

Objective: This study tested the hypothesis that systemic inflammation is inversely associated with haemoglobin levels in adolescent girls in India. Methods: The study population consisted of adolescent girls aged between 10 and 19years living in a r... Read More about Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study.

Do working practices of cancer nurse specialists improve clinical outcomes? Retrospective cohort analysis from the English National Lung Cancer Audit (2020)
Journal Article
Stewart, I., Leary, A., Khakwani, A., Borthwick, D., Tod, A., Hubbard, R., …Tata, L. J. (2021). Do working practices of cancer nurse specialists improve clinical outcomes? Retrospective cohort analysis from the English National Lung Cancer Audit. International Journal of Nursing Studies, 118, Article 103718. https://doi.org/10.1016/j.ijnurstu.2020.103718

Background
Cancer nurse specialists are advanced practitioners who offer continuity of care and expert support for people diagnosed with specific cancers. Health Education England's Cancer Workforce Plan prioritises expansion of cancer nurse special... Read More about Do working practices of cancer nurse specialists improve clinical outcomes? Retrospective cohort analysis from the English National Lung Cancer Audit.

Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study (2019)
Journal Article
Ahankari, A. S., Tata, L. J., & Fogarty, A. W. (2020). Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study. Maternal and Child Nutrition, 16(2), Article e12908. https://doi.org/10.1111/mcn.12908

Objective:
We aimed to explore the association of physical parameters with haemoglobin (Hb) levels to test the hypothesis that impaired physical development is associated with anaemia.

Methods:
A cross-sectional survey study recruited adolescent... Read More about Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study.

Clinical management of nausea and vomiting in pregnancy and hyperemesis gravidarum across primary and secondary care: a population based study (2019)
Journal Article
Fiaschi, L., Nelson-Piercy, C., Deb, S., King, R., & Tata, L. (2019). Clinical management of nausea and vomiting in pregnancy and hyperemesis gravidarum across primary and secondary care: a population based study. BJOG: An International Journal of Obstetrics and Gynaecology, 126(10), 1201-1211. https://doi.org/10.1111/1471-0528.15662

Objectives: To assess how nausea and vomiting in pregnancy (NVP) and hyperemesis gravidarum (HG) are managed and treated across primary and secondary care.

Design: Population-based pregnancy cohort
Setting: Medical records (CPRD-GOLD) from Englan... Read More about Clinical management of nausea and vomiting in pregnancy and hyperemesis gravidarum across primary and secondary care: a population based study.

Stillbirth among women prescribed nicotine replacement therapy in pregnancy: analysis of a large UK pregnancy cohort (2018)
Journal Article
Dhalwani, N. N., Szatkowski, L., Coleman, T., Fiaschi, L., & Tata, L. J. (2019). Stillbirth among women prescribed nicotine replacement therapy in pregnancy: analysis of a large UK pregnancy cohort. Nicotine and Tobacco Research, 21(4), 409–415. https://doi.org/10.1093/ntr/nty019

Objective: To compare risk of stillbirth between maternal smokers and those prescribed NRT during pregnancy.

Design: Cross-sectional analysis nested in a pregnancy cohort with longitudinal routinely-recorded medical data.

Setting: United Kingdo... Read More about Stillbirth among women prescribed nicotine replacement therapy in pregnancy: analysis of a large UK pregnancy cohort.

Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data (2017)
Journal Article
Achana, F., Fleming, K., Tata, L., Sultan, A. A., & Petrou, S. (2018). Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data. BJOG: An International Journal of Obstetrics and Gynaecology, 125(7), 874-883. https://doi.org/10.1111/1471-0528.14950

Objective
To estimate resource use and costs associated with peripartum hysterectomy for the English National Health Service.

Design/Setting
Analysis of linked Clinical Practice Research Datalink and Hospital Episodes Statistics (CPRD‐HES) data.... Read More about Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data.

Risk factors for maternal anaemia and low birth weight in pregnant women living in rural India: a prospective cohort study (2017)
Journal Article
Ahankari, A. S., Myles, P. R., Dixit, J., Tata, L. J., & Fogarty, A. W. (2017). Risk factors for maternal anaemia and low birth weight in pregnant women living in rural India: a prospective cohort study. Public Health, 151, 63-73. https://doi.org/10.1016/j.puhe.2017.06.023

Objective: The aim of this prospective study was to estimate the prevalence and risk factors for maternal anaemia and low birth weight in pregnant women living in Maharashtra state, India.

Study design: Prospective study
Methods: Women between 3... Read More about Risk factors for maternal anaemia and low birth weight in pregnant women living in rural India: a prospective cohort study.