All Outputs (5)

Seasonality as a driver of pH1N12009 influenza vaccination campaign impact (2023)
Journal Article
Bolton, K. J., McCaw, J. M., Dafilis, M. P., McVernon, J., & Heffernan, J. M. (2023). Seasonality as a driver of pH1N12009 influenza vaccination campaign impact. Epidemics, 45, Article 100730. https://doi.org/10.1016/j.epidem.2023.100730

Although the most recent respiratory virus pandemic was triggered by a Coronavirus, sustained and elevated prevalence of highly pathogenic avian influenza viruses able to infect mammalian hosts highlight the continued threat of pandemics of influenza... Read More about Seasonality as a driver of pH1N12009 influenza vaccination campaign impact.

Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university (2023)
Journal Article
Fairbanks, E. L., Bolton, K. J., Jia, R., Figueredo, G. P., Knight, H., & Vedhara, K. (2023). Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university. Epidemics, 43, Article 100688. https://doi.org/10.1016/j.epidem.2023.100688

We survey 62 users of a university asymptomatic SARS-CoV-2 testing service on details of their activities, protective behaviours and contacts in the 7 days prior to receiving a positive or negative SARS-CoV-2 PCR test result in the period October 202... Read More about Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university.

SARS-CoV-2 infection in UK university students: Lessons from September-December 2020 and modelling insights for future student return (2021)
Journal Article
Enright, J., Hill, E. M., Stage, H. B., Bolton, K. J., Nixon, E. J., Fairbanks, E. L., …Tildesley, M. J. (2021). SARS-CoV-2 infection in UK university students: Lessons from September-December 2020 and modelling insights for future student return. Royal Society Open Science, 8(8), Article 210310. https://doi.org/10.1098/rsos.210310

In this paper, we present work on SARS-CoV-2 transmission in UK higher education settings using multiple approaches to assess the extent of university outbreaks, how much those outbreaks may have led to spillover in the community, and the expected ef... Read More about SARS-CoV-2 infection in UK university students: Lessons from September-December 2020 and modelling insights for future student return.

Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control (2015)
Journal Article
Bolton, K. J., McCaw, J. M., Brown, L., Jackson, D., Kedzierska, K., & McVernon, J. (2015). Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control. PLoS ONE, 10(3), Article e0120138. https://doi.org/10.1371/journal.pone.0120138

Vaccines that trigger an influenza-specific cytotoxic T cell (CTL) response may aid pandemic control by limiting the transmission of novel influenza A viruses (IAV). We consider interventions with hypothetical CTL-inducing vaccines in a range of epid... Read More about Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control.

The influence of changing host immunity on 1918–19 pandemic dynamics (2014)
Journal Article
Bolton, K., McCaw, J., McVernon, J., & Mathews, J. (2014). The influence of changing host immunity on 1918–19 pandemic dynamics. Epidemics, 8, 18-27. https://doi.org/10.1016/j.epidem.2014.07.004

The sociological and biological factors which gave rise to the three pandemic waves of Spanish influenza in England during 1918–19 are still poorly understood. Symptom reporting data available for a limited set of locations in England indicates that... Read More about The influence of changing host immunity on 1918–19 pandemic dynamics.