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All Outputs (141)

An interview study of the experiences of cellulitis diagnosis amongst health care professionals (2020)
Journal Article
Patel, M., Ing Lee, S., Levell, N. J., Smart, P., Kai, J., Thomas, K. S., & Leighton, P. (2020). An interview study of the experiences of cellulitis diagnosis amongst health care professionals. BMJ Open, 10(10), Article e034692. https://doi.org/10.1136/+bmjopen-2019-034692

Objectives: To explore healthcare professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis.

Setting: UK nationwide.

Participants: 20 qualified HCPs, who had a minimum of 2 years clinical experience as an HCP... Read More about An interview study of the experiences of cellulitis diagnosis amongst health care professionals.

An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK (2020)
Journal Article
Patel, M., Lee, S., Levell, N., Smart, P., Kai, J., Thomas, K., & Leighton, P. (2020). An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK. BMJ Open, 10, Article e034692. https://doi.org/10.1136/bmjopen-2019-034692

Objectives: To explore health care professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis.

Setting: UK nationwide.

Participants: 20 qualified HCPs, who had a minimum of two years clinical experience as a... Read More about An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK.

Randomised controlled trial of topical corticosteroid and home‐based narrowband UVB for active and limited vitiligo: results of the HI‐Light Vitiligo trial (2020)
Journal Article
Thomas, K., Batchelor, J. M., Akram, P., Chalmers, J. R., Haines, R., Meakin, G. D., …Montgomery, A. A. (2021). Randomised controlled trial of topical corticosteroid and home‐based narrowband UVB for active and limited vitiligo: results of the HI‐Light Vitiligo trial. British Journal of Dermatology, 184(5), 828-839. https://doi.org/10.1111/bjd.19592

Background
Evidence for the effectiveness of vitiligo treatments is limited.

Objectives
To determine effectiveness of (a) hand‐held narrowband‐UVB (NB‐UVB) and (b) combination of potent topical corticosteroid (TCS) and NB‐UVB compared to TCS, fo... Read More about Randomised controlled trial of topical corticosteroid and home‐based narrowband UVB for active and limited vitiligo: results of the HI‐Light Vitiligo trial.

Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England (2020)
Journal Article
Persson, M. S., Harman, K. E., Vinogradova, Y., Langan, S. M., Hippisley-Cox, J., Thomas, K. S., & Gran, S. (2020). Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England. BMJ Open, 10(7), e035934. https://doi.org/10.1136/bmjopen-2019-035934

Objectives: The validity of bullous pemphigoid and pemphigus vulgaris recording in routinely collected healthcare data in the UK is unknown. We assessed the positive predictive value (PPV) for bullous pemphigoid and pemphigus vulgaris primary care Re... Read More about Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England.

Views and experiences of managing eczema: systematic review and thematic synthesis of qualitative studies (2020)
Journal Article
Teasdale, E., Muller, I., Sivyer, K., Ghio, D., Greenwell, K., Wilczynska, S., …Santer, M. (2021). Views and experiences of managing eczema: systematic review and thematic synthesis of qualitative studies. British Journal of Dermatology, 184(4), 627-637. https://doi.org/10.1111/bjd.19299

Background

The number of qualitative studies on eczema has increased rapidly in recent years. Systematically reviewing these can provide greater understandings of people’s perceptions of eczema and eczema treatments.

Objectives

We sought to... Read More about Views and experiences of managing eczema: systematic review and thematic synthesis of qualitative studies.

Incidence, prevalence and mortality of bullous pemphigoid in England 1998–2017: a population-based cohort study* (2020)
Journal Article
Persson, M. S., Harman, K. E., Vinogradova, Y., Langan, S. M., Thomas, K. S., Hippisley-Cox, J., & Gran, S. (2021). Incidence, prevalence and mortality of bullous pemphigoid in England 1998–2017: a population-based cohort study*. British Journal of Dermatology, 184(1), 68-77. https://doi.org/10.1111/bjd.19022

Background: A rising incidence and high mortality were found for bullous pemphigoid (BP) over a decade ago in the UK. Updated estimates of its epidemiology are required to understand the healthcare needs of an ageing population. Objectives: To determ... Read More about Incidence, prevalence and mortality of bullous pemphigoid in England 1998–2017: a population-based cohort study*.

Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial (2020)
Journal Article
Chalmers, J. R., Haines, R. H., Bradshaw, L. E., Montgomery, A. A., Thomas, K. S., Brown, S. J., …Williams, H. C. (2020). Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial. Lancet, 395(10228), 962-972. https://doi.org/10.1016/S0140-6736%2819%2932984-8

Background

Skin barrier dysfunction precedes eczema development. We tested whether daily use of emollient in the first year could prevent eczema in high-risk children.

Methods

We did a multicentre, pragmatic, parallel-group, randomised contr... Read More about Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial.

Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative (2020)
Journal Article
Leshem, Y. A., Chalmers, J. R., Apfelbacher, C., Furue, M., Gerbens, L. A., Prinsen, C. A., …Simpson, E. L. (2020). Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative. Journal of The American Academy of Dermatology, 82(5), 1181-1186. https://doi.org/10.1016/j.jaad.2019.12.055

Background: Measuring patient-centered outcomes in clinical practice is valuable for monitoring patients and advancing real-world research. A new initiative from the Harmonising Outcome Measures for Eczema (HOME) group aims to recommend what might be... Read More about Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative.

Confidence of recurrent cellulitis self-diagnosis among people with lymphoedema: a qualitative interview study (2019)
Journal Article
Patel, M., Lee, S. I., Levell, N. J., Smart, P., Kai, J., Thomas, K. S., & Leighton, P. (2020). Confidence of recurrent cellulitis self-diagnosis among people with lymphoedema: a qualitative interview study. British Journal of General Practice, 70(691), e130-e137. https://doi.org/10.3399/bjgp19X707909

© British Journal of General Practice 2020. BACKGROUND: Cellulitis can sometimes be challenging for healthcare professionals to diagnose, with no validated diagnostic criteria available. Supporting healthcare professionals to make a more accurate dia... Read More about Confidence of recurrent cellulitis self-diagnosis among people with lymphoedema: a qualitative interview study.

Development and initial testing of a new instrument to measure the experience of eczema control in adults and children: Recap of atopic eczema (RECAP) (2019)
Journal Article
Howells, L. M., Chalmers, J. R., Gran, S., Ahmed, A., Apfelbacher, C., Burton, T., …Thomas, K. S. (2020). Development and initial testing of a new instrument to measure the experience of eczema control in adults and children: Recap of atopic eczema (RECAP). British Journal of Dermatology, 183(3), 524-536. https://doi.org/10.1111/bjd.18780

Background: Eczema control has been identified as an important outcome by key stakeholders in eczema research (including patients, carers, healthcare professionals and researchers) but no validated instruments for the domain have been identified. Obj... Read More about Development and initial testing of a new instrument to measure the experience of eczema control in adults and children: Recap of atopic eczema (RECAP).

Best emollients for eczema (BEE) – comparing four types of emollients in children with eczema: protocol for randomised trial and nested qualitative study (2019)
Journal Article
Ridd, M. J., Wells, S., Edwards, L., Santer, M., MacNeill, S., Sanderson, E., …Thomas, K. S. (2019). Best emollients for eczema (BEE) – comparing four types of emollients in children with eczema: protocol for randomised trial and nested qualitative study. BMJ Open, 9(11), Article e033387. https://doi.org/10.1136/bmjopen-2019-033387

Introduction Atopic dermatitis/eczema affects around 20% of children and is characterised by inflamed, dry, itchy skin. Guidelines recommend ‘leave-on’ emollients that are applied directly to the skin to add or trap moisture and used regularly, they... Read More about Best emollients for eczema (BEE) – comparing four types of emollients in children with eczema: protocol for randomised trial and nested qualitative study.

Protocol for a case-control diagnostic accuracy study to develop diagnostic criteria for psoriasis in children (DIPSOC study): a multicentre study recruiting in UK paediatric dermatology clinics (2019)
Journal Article
Burden-Teh, E., Murphy, R., Gran, S., Nijsten, T., Hughes, C., & Thomas, K. S. (2019). Protocol for a case-control diagnostic accuracy study to develop diagnostic criteria for psoriasis in children (DIPSOC study): a multicentre study recruiting in UK paediatric dermatology clinics. BMJ Open, 9(8), e028689. https://doi.org/10.1136/bmjopen-2018-028689

Introduction Diagnosing psoriasis in children can be challenging. Early and accurate diagnosis is important to ensure patients receive psoriasis specific treatment and monitoring. It is recognised that the physical, psychological, quality of life, fi... Read More about Protocol for a case-control diagnostic accuracy study to develop diagnostic criteria for psoriasis in children (DIPSOC study): a multicentre study recruiting in UK paediatric dermatology clinics.

Protocol for an outcome assessor-blinded pilot randomised controlled trial of an ion-exchange water softener for the prevention of atopic eczema in neonates, with an embedded mechanistic study: The SOFtened waTER for eczema prevention trial (SOFTER) (2019)
Journal Article
Jabbar-Lopez, Z., Gurung, N., Greenblatt, D., Briley, A., Chalmers, J., Thomas, K., …Flohr, C. (2019). Protocol for an outcome assessor-blinded pilot randomised controlled trial of an ion-exchange water softener for the prevention of atopic eczema in neonates, with an embedded mechanistic study: The SOFtened waTER for eczema prevention trial (SOFTER). BMJ Open, 9(8), Article e027168. https://doi.org/10.1136/bmjopen-2018-027168

© 2019 Author(s). Introduction Atopic eczema affects 20% of UK children, and environmental factors are important in its aetiology. Several observational studies suggest an increased risk of atopic eczema in children living in hard water areas. The So... Read More about Protocol for an outcome assessor-blinded pilot randomised controlled trial of an ion-exchange water softener for the prevention of atopic eczema in neonates, with an embedded mechanistic study: The SOFtened waTER for eczema prevention trial (SOFTER).

Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials (2019)
Journal Article
Mousoulis, C., Thomas, K., Leighton, P., Deshmukh, S., Grindlay, D., & Karantana, A. (2020). Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials. Journal of Hand Surgery (European Volume), 45(2), 111-118. https://doi.org/10.1177/1753193419865897

The aim of this study was to identify and assess all existing randomized studies on treatment interventions for hand fractures and joint injuries, to inform practice and plan future research. PubMed, Cochrane CENTRAL, MEDLINE and Embase were searche... Read More about Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials.

Different strategies for using topical corticosteroids in people with eczema (2019)
Journal Article
Chalmers, J. R., Axon, E., Harvey, J., Santer, M., Ridd, M. J., Lawton, S., Langan, S., Roberts, A., Ahmed, A., Muller, I., Long, C. M., Panda, S., Chernyshov, P., Carter, B., Williams, H. C., & Thomas, K. S. (2019). Different strategies for using topical corticosteroids in people with eczema. Cochrane Database of Systematic Reviews, 2019(6), Article CD013356. https://doi.org/10.1002/14651858.CD013356

© 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To establish the effectiveness and safety of different ways of using topical corticoster... Read More about Different strategies for using topical corticosteroids in people with eczema.

Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council (2019)
Journal Article
Burden‐Teh, E., Thomas, K. S., Gran, S., & Murphy, R. (2019). Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council. British Journal of Dermatology, 181(4), 856-857. https://doi.org/10.1111/bjd.17994

Psoriasis in children can be a challenging diagnosis: the clinical presentation is often more subtle, may occur in covered sites and can be an unexpected diagnosis as psoriasis if often thought to occur at older ages. Poor recognition and delayed dia... Read More about Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council.

Uncertainty about cellulitis and unmet patient information needs: a mixed methods study in primary and secondary care (2019)
Journal Article
Teasdale, E., Lalonde, A., Muller, I., Chalmers, J., Smart, P., Hooper, J., …Santer, M. (2019). Uncertainty about cellulitis and unmet patient information needs: a mixed methods study in primary and secondary care. British Journal of General Practice, 69(681), e279-e286. https://doi.org/10.3399/bjgp19X701873

Background: Cellulitis is a painful infection of the skin and underlying tissues, commonly affecting the lower leg: approximately a third of people experience recurrence. Patients’ ability to recover from cellulitis or prevent recurrence is likely to... Read More about Uncertainty about cellulitis and unmet patient information needs: a mixed methods study in primary and secondary care.