Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT
(2024)
Journal Article
Santer, M., Lawrence, M., Pyne, S., Renz, S., L Stuart, B., Sach, T., Ridd, M., S Thomas, K., Nuttall, J., Permyakova, N., Eminton, Z., Francis, N., Little, P., Muller, I., Soulsby, I., Thomas, K., Griffiths, G., & M Layton, A. (2024). Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT. Health Technology Assessment, 28(56), https://doi.org/10.3310/MYJT6804
Background
Acne is common, can cause significant impact on quality of life and is a frequent reason for long-term antibiotic use. Spironolactone has been prescribed for acne in women for many years, but robust evidence is lacking.
Objective
To e...
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