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All Outputs (8)

Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT (2024)
Journal Article
Santer, M., Lawrence, M., Pyne, S., Renz, S., L Stuart, B., Sach, T., Ridd, M., S Thomas, K., Nuttall, J., Permyakova, N., Eminton, Z., Francis, N., Little, P., Muller, I., Soulsby, I., Thomas, K., Griffiths, G., & M Layton, A. (2024). Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT. Health Technology Assessment, 28(56), https://doi.org/10.3310/MYJT6804

Background
Acne is common, can cause significant impact on quality of life and is a frequent reason for long-term antibiotic use. Spironolactone has been prescribed for acne in women for many years, but robust evidence is lacking.

Objective
To e... Read More about Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT.

Rapid Eczema Trials: Addressing patient priorities from the eczema priority setting partnership (2024)
Journal Article
Campbell, E. L., Fong, W. C. G., Roberts, A., & Thomas, K. S. (2024). Rapid Eczema Trials: Addressing patient priorities from the eczema priority setting partnership. British Journal of Dermatology, Article ljae362. https://doi.org/10.1093/bjd/ljae362

In this letter, we describe the Rapid Eczema Trials co-production project, which aims to plug some of the research gaps that remain following the 2011 James Lind Alliance Eczema Priority Setting Partnership (PSP) exercise. We highlight similarities b... Read More about Rapid Eczema Trials: Addressing patient priorities from the eczema priority setting partnership.

Capturing and reporting topical treatment use in childhood eczema: lessons for data collection in eczema trials (2024)
Journal Article
Memory, K. E., Macneill, S. J., Thomas, K. S., Santer, M., & Ridd, M. J. (2024). Capturing and reporting topical treatment use in childhood eczema: lessons for data collection in eczema trials. Clinical and Experimental Dermatology, https://doi.org/10.1093/ced/llae328

Background

Emollients and topical corticosteroids (TCS) prevent and treat flares in eczema. However, topical treatment use is poorly recorded and reported in clinical trials. There is no clear consensus of how best to capture and summarise topical... Read More about Capturing and reporting topical treatment use in childhood eczema: lessons for data collection in eczema trials.

Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT (2024)
Journal Article
Wyatt, L. A., Bradshaw, L. E., Brown, S. J., Haines, R. H., Montgomery, A. A., Perkin, M. R., Sach, T. H., Lawton, S., Flohr, C., Ridd, M. J., Chalmers, J. R., Brooks, J., Swinden, R., Mitchell, E. J., Tarr, S., Jay, N., Thomas, K. S., Allen, H., Cork, M. J., Kelleher, M. M., …Williams, H. C. (2024). Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT. Health Technology Assessment, 28(29), 1-116. https://doi.org/10.3310/rhdn9613

Background

Atopic eczema is a common childhood skin problem linked with asthma, food allergy and allergic rhinitis that impairs quality of life.

Objectives

To determine whether advising parents to apply daily emollients in the first year can... Read More about Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT.

A multifaceted and standardised approach is needed to improve acne severity assessment in clinical practice: an online survey of UK health professionals (2024)
Journal Article
Masterson, N., Burden-Teh, E., Healy, E., Hepburn, T., Layfield, C., Layton, A., Leighton, P., Leng, S., Mitchell, E., Northover, G., Penzer-Hick, R., Price, W., Radley, K., Ramesh, G., Ravenscroft, J. C., Sach, T., Sadiq, S., Santer, M., Thomas, K. S., Thompson, A., …the Acne-ID Trial Development Team. (2024). A multifaceted and standardised approach is needed to improve acne severity assessment in clinical practice: an online survey of UK health professionals. Clinical and Experimental Dermatology, https://doi.org/10.1093/ced/llae180

Cost-effectiveness of two online interventions supporting self-care for eczema for parents/carers and young people (2024)
Journal Article
Sach, T. H., Onoja, M., Clarke, H., Santer, M., Muller, I., Becque, T., …Thomas, K. S. (2024). Cost-effectiveness of two online interventions supporting self-care for eczema for parents/carers and young people. European Journal of Health Economics, https://doi.org/10.1007/s10198-023-01649-9

Objective: To estimate the cost-effectiveness of online behavioral interventions (EczemaCareOnline.org.uk) designed to support eczema self-care management for parents/carers and young people from an NHS perspective. Methods: Two within-trial economic... Read More about Cost-effectiveness of two online interventions supporting self-care for eczema for parents/carers and young people.

How can community pharmacists be supported to manage skin conditions? A multistage stakeholder research prioritisation exercise (2024)
Journal Article
Harvey, J., Shariff, Z., Anderson, C., Boyd, M. J., Ridd, M. J., Santer, M., …Leighton, P. (2024). How can community pharmacists be supported to manage skin conditions? A multistage stakeholder research prioritisation exercise. BMJ Open, 14(1), Article e071863. https://doi.org/10.1136/bmjopen-2023-071863

Objective: To establish research priorities which will support the development and delivery of community pharmacy initiatives for the management of skin conditions. Design: An iterative, multistage stakeholder consultation consisting of online survey... Read More about How can community pharmacists be supported to manage skin conditions? A multistage stakeholder research prioritisation exercise.