Skip to main content

Research Repository

Advanced Search

All Outputs (24)

Prevalence, Incidence, and Mortality of Raynaud’s phenomenon, Sjögren’s syndrome, and scleroderma: an umbrella review of systematic reviews (2024)
Journal Article
Chen, A., Lax, S. J., Grainge, M. J., Lanyon, P. C., & Pearce, F. A. (2024). Prevalence, Incidence, and Mortality of Raynaud’s phenomenon, Sjögren’s syndrome, and scleroderma: an umbrella review of systematic reviews. Rheumatology Advances in Practice, 8(3), Article rkae086. https://doi.org/10.1093/rap/rkae086

Objectives:

To comprehensively review systematic reviews of prevalence, incidence, and mortality of Raynaud’s, Sjögren’s, and Scleroderma, and to identify any research gaps.

Methods:

An umbrella review of English language systematic review... Read More about Prevalence, Incidence, and Mortality of Raynaud’s phenomenon, Sjögren’s syndrome, and scleroderma: an umbrella review of systematic reviews.

A meta-analysis and systematic review of the use of transition tools for patients transitioning from paediatric to adult rheumatology services (2024)
Journal Article
Griffin, K., Pearce, F., & Packham, J. (in press). A meta-analysis and systematic review of the use of transition tools for patients transitioning from paediatric to adult rheumatology services. Rheumatology Advances in Practice, https://doi.org/10.1093/rap/rkae130

Introduction: Transition from paediatric to adult care can be challenging, but transition tools are designed to increase successful rates of transfer.
Objectives: Conduct a meta-analysis and systematic review into the use of transition tools on tran... Read More about A meta-analysis and systematic review of the use of transition tools for patients transitioning from paediatric to adult rheumatology services.

Long-term outcomes (beyond 5 years) of liver transplant recipients--a transatlantic multicenter study (2023)
Journal Article
Palaniyappan, N., Peach, E., Pearce, F., Dhaliwal, A., Campos-Varela, I., Cant, M. R., …Aravinthan, A. D. (2024). Long-term outcomes (beyond 5 years) of liver transplant recipients--a transatlantic multicenter study. Liver Transplantation, 30(2), 170-181. https://doi.org/10.1097/LVT.0000000000000244

The long-term (>5y) outcomes following liver transplantation (LT) have not been extensively reported. The aim was to evaluate outcomes of LT recipients who have survived the first 5 years. A multicenter retrospective analysis of prospectively collect... Read More about Long-term outcomes (beyond 5 years) of liver transplant recipients--a transatlantic multicenter study.

Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY (2023)
Journal Article
Pearce, F. A., Lim, S. H., Bythell, M., Lanyon, P., Hogg, R., Taylor, A., Powter, G., Cooke, G. S., Ward, H., Chilcot, J., Thomas, H., Mumford, L., McAdoo, S. P., Pettigrew, G. J., Lightstone, L., & Willicombe, M. (2023). Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY. The Lancet Rheumatology, 5(8), E461-E473. https://doi.org/10.1016/S2665-9913%2823%2900160-1

Background: In the UK, additional COVID-19 vaccine booster doses and treatments are offered to people who are immunosuppressed to protect against severe COVID-19, but how best to choose the individuals that receive these vaccine booster doses and tre... Read More about Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY.

Validation of methods to identify people with idiopathic inflammatory myopathies using hospital episode statistics (2022)
Journal Article
Hannah, J., Gordon, P., Galloway, J., Rutter, M., Peach, E., Rooney, M., Stilwell, P., Grainge, M., Lanyon, P., Bythell, M., & Pearce, F. (2022). Validation of methods to identify people with idiopathic inflammatory myopathies using hospital episode statistics. Rheumatology Advances in Practice, 6(3), Article rkac102. https://doi.org/10.1093/rap/rkac102

Objective: Hospital episode statistics (HES) are routinely recorded at every hospital admission within the National Health Service (NHS) in England. This study validates diagnostic ICD-10 codes within HES as a method of identifying cases of idiopathi... Read More about Validation of methods to identify people with idiopathic inflammatory myopathies using hospital episode statistics.

COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis (2022)
Journal Article
Cordtz, R., Kristensen, S., Westermann, R., Duch, K., Pearce, F., Lindhardsen, J., …Dreyer, L. (2023). COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis. Rheumatology, 62(1), 77-88. https://doi.org/10.1093/rheumatology/keac241

Objectives: The objectives of this study were to investigate the incidence of COVID-19 hospitalization in unvaccinated and vaccinated patients with RA compared with matched controls, and in patients with RA according to DMARD treatment.

Methods: T... Read More about COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis.

Estimating the clinical prevalence of Wilson’s disease in the UK (2021)
Journal Article
Wijayasiri, P., Hayre, J., Nicholson, E. S., Kaye, P., Wilkes, E. A., Evans, J., …Aravinthan, A. D. (2021). Estimating the clinical prevalence of Wilson’s disease in the UK. JHEP Reports, 3(5), Article 100329. https://doi.org/10.1016/j.jhepr.2021.100329

Background and Aim
The clinical prevalence of Wilson’s disease (WD) in the UK remains unknown. The estimated genetic prevalence in the UK, 142/million, is higher than the clinical prevalence (15/million) reported in other European studies. The aim o... Read More about Estimating the clinical prevalence of Wilson’s disease in the UK.

Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis (2021)
Journal Article
Johnston, P. I., Wright, S. W., Orr, M., Pearce, F. A., Stevens, J. W., Hubbard, R. B., & Collini, P. J. (2021). Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis. AIDS, 35(6), 957-970. https://doi.org/10.1097/QAD.0000000000002815

Objective and design: People living with HIV (PLH) suffer disproportionately from the chronic diseases exacerbated by smoking tobacco. We performed a systematic review and meta-analysis to establish the relative prevalence of smoking among PLH.

M... Read More about Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis.

BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK (2020)
Journal Article
Pearce, F. A., Rutter, M., Sandhu, R., Batten, R. L., Garner, R., Little, J., …Lanyon, P. C. (2021). BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK. Rheumatology, 60(3), 1480-1490. https://doi.org/10.1093/rheumatology/keaa759

Objectives: To assess the baseline care provided to patients with SLE attending UK Rheumatology units, audited against standards derived from the recently published BSR guideline for the management of adults with SLE, the NICE technology appraisal fo... Read More about BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK.

Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic (2020)
Journal Article
Peach, E., Rutter, M., Lanyon, P., Grainge, M. J., Hubbard, R., Aston, J., …Pearce, F. (2021). Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic. Rheumatology, 60(4), 1902–1909. https://doi.org/10.1093/rheumatology/keaa855

Objectives: To quantify the risk of death among people with rare autoimmune rheumatic diseases (RAIRD) during the UK 2020 COVID-19 pandemic compared with the general population, and compared with their pre-COVID risk. Methods: We conducted a cohort s... Read More about Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic.

Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis (2020)
Journal Article
Smith, R. M., Jones, R. B., Specks, U., Bond, S., Nodale, M., Aljayyousi, R., …Jayne, D. (2020). Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis. Annals of the Rheumatic Diseases, 79(9), 1243-1249. https://doi.org/10.1136/annrheumdis-2019-216863

Objectives: Evaluation of rituximab and glucocorticoids as therapy to induce remission after relapse in ANCA-associated vasculitis (AAV) in a prospective observational cohort of patients enrolled into the induction phase of the RITAZAREM trial.

Me... Read More about Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis.

Outcomes and compliance with standards of care in ANCA-associated vasculitis: insights from a large multi-region audit (2018)
Journal Article
Pearce, F., McGrath, C., Sandhu, R., Packham, J. C., Watts, R., Rhodes, B., Reem, A.-J., Harper, L., Obrenovic, K., & Lanyon, P. C. (2018). Outcomes and compliance with standards of care in ANCA-associated vasculitis: insights from a large multi-region audit. Rheumatology Advances in Practice, 2(2), 1-7. https://doi.org/10.1093/rap/rky025

Objectives: We aimed to conduct a large audit of routine care for patients with ANCA-associated vasculitis (AAV).
Methods: We invited all 34 hospitals within one health region in England to undertake a retrospective case note audit of all patients n... Read More about Outcomes and compliance with standards of care in ANCA-associated vasculitis: insights from a large multi-region audit.

Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink (2018)
Journal Article
Pearce, F. A., Lanyon, P. C., Watts, R. A., Grainge, M. J., Abhishek, A., & Hubbard, R. B. (2018). Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink. Rheumatology, 57(10), 1873. https://doi.org/10.1093/rheumatology/key249

This is a correction to:
Rheumatology, Volume 57, Issue 6, June 2018, Pages 1002–1010, https://doi.org/10.1093/rheumatology/kex512

Correction to: The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink (2018)
Journal Article
Royle, J. G., Lanyon, P. C., Grainge, M. J., Abhishek, A., & Pearce, F. A. (2018). Correction to: The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink. Clinical Rheumatology, 37(9), 2601. https://doi.org/10.1007/s10067-018-4219-7

© 2018, International League of Associations for Rheumatology (ILAR). The above article originally published with an error present in the 2nd sentence in the 4th paragraph of the discussion section and is now presented correctly in this article. The... Read More about Correction to: The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink.

The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink (2018)
Journal Article
Royle, J. G., Lanyon, P. C., Grainge, M. J., Abhishek, A., & Pearce, F. A. (2018). The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink. Clinical Rheumatology, 37(8), 2103-2111. https://doi.org/10.1007/s10067-018-4182-3

Abstract
To estimate the incidence, prevalence, and survival of systemic sclerosis in the United Kingdom. We conducted a historical cohort study using data from the Clinical Practice Research Datalink (CPRD). We calculated the incidence and survival... Read More about The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink.

The incidence, prevalence and survival of systemic sclerosis in the UK Clinical Practice Research Datalink (2018)
Journal Article
Royle, J. G., Lanyon, P. C., Grainge, M. J., Abhishek, A., & Pearce, F. A. (2018). The incidence, prevalence and survival of systemic sclerosis in the UK Clinical Practice Research Datalink. Clinical Rheumatology, 37(8), 2103–2111. https://doi.org/10.1007/s10067-018-4182-3

Objective: To estimate the incidence, prevalence and survival of systemic sclerosis in the United Kingdom.
Methods: We conducted a historical cohort study using data from the Clinical Practice Research Datalink (CPRD). We calculated the incidence an... Read More about The incidence, prevalence and survival of systemic sclerosis in the UK Clinical Practice Research Datalink.

Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink (2018)
Journal Article
Pearce, F. A., Lanyon, P. C., Watts, R. A., Grainge, M. J., Abhishek, A., & Hubbard, R. B. (2018). Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink. Rheumatology, 57(6), 1002-1010. https://doi.org/10.1093/rheumatology/kex512

Objectives:
We aimed to provide insights into the aetiology of granulomatosis with polyangiitis (GPA), by conducting a large case–control study using a general population-based, prospectively collected database of healthcare records.

Methods:
We... Read More about Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink.

Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis (2017)
Journal Article
La-Crette, J., Royle, J., Lanyon, P. C., Ferraro, A., Butler, A., & Pearce, F. A. (2018). Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis. Clinical Rheumatology, 37(4), 1085–1090. https://doi.org/10.1007/s10067-017-3944-7

Objectives We aimed to compare risk of death, relapse, neutropenia and infection requiring hospital admission between unselected ANCA-associated vasculitis (AAV) patients according to whether cyclophosphamide induction was by daily oral (PO) or pulse... Read More about Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis.