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All Outputs (48)

A randomised feasibility study assessing an intervention to keep adults physically active after falls management exercise programmes end (2020)
Journal Article
Audsley, S., Kendrick, D., Logan, P., Jones, M., & Orton, E. (2020). A randomised feasibility study assessing an intervention to keep adults physically active after falls management exercise programmes end. Pilot and Feasibility Studies, 6, Article 37. https://doi.org/10.1186/s40814-020-00570-9

Background: Physical inactivity contributes to disability and falls in older adults. Falls prevention exercise (FaME) programmes improve physical activity, physical function and reduce falling rates. Improvements in physical function reduce, and fall... Read More about A randomised feasibility study assessing an intervention to keep adults physically active after falls management exercise programmes end.

Economic evaluation of the OSAC randomised controlled trial: Oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care (2020)
Journal Article
Carroll, F. E., Moure-Fernandez, A., Hollinghurst, S., Downing, H., Young, G., Brookes, S., May, M., El-Gohary, M., Harnden, A., Kendrick, D., Lafond, N., Little, P., Moore, M., Orton, E., Thompson, M., Timmins, D., Wang, K., & Hay, A. D. (2020). Economic evaluation of the OSAC randomised controlled trial: Oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care. BMJ Open, 10(2), Article e033567. https://doi.org/10.1136/bmjopen-2019-033567

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. Objective To estimate the costs and outcomes associated with treating non-asthmatic adults (nor suffering from other lung-disease) presenting to primary care wit... Read More about Economic evaluation of the OSAC randomised controlled trial: Oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care.

Understanding pathways to social inequalities in childhood unintentional injuries: findings from the UK Millennium Cohort Study (2019)
Journal Article
Campbell, M., Lai, E. T., Pearce, A., Orton, E., Kendrick, D., Wickham, S., & Taylor-Robinson, D. C. (2019). Understanding pathways to social inequalities in childhood unintentional injuries: findings from the UK Millennium Cohort Study. BMC Pediatrics, 19, Article 150. https://doi.org/10.1186/s12887-019-1514-7

Background: Childhood unintentional injuries (UI) are common but continue to happen more often to children living in less advantaged socioeconomic circumstances (SEC). Our aim was to explore how early life factors mediate the association between SEC... Read More about Understanding pathways to social inequalities in childhood unintentional injuries: findings from the UK Millennium Cohort Study.

“We got more than we expected.” Older people’s experiences of falls-prevention exercise interventions and implications for practice. A qualitative study. (2019)
Journal Article
Lafond, N., Maula, A., Iliffe, S., Vedhara, K., Audsley, S., Kendrick, D., & Orton, E. (2019). “We got more than we expected.” Older people’s experiences of falls-prevention exercise interventions and implications for practice. A qualitative study. Primary Health Care Research and Development, 20, Article e103. https://doi.org/10.1017/S1463423619000379

Aim: To explore the experiences of older adults participating in strength and balance exercise programmes and understand participants’ rationale for programme uptake and completion.

Background: Regular physical activity, specifically strength an... Read More about “We got more than we expected.” Older people’s experiences of falls-prevention exercise interventions and implications for practice. A qualitative study..

Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis (2018)
Journal Article
Otete, H., Fleming, K. M., West, J., & Orton, E. (2019). Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis. Alcohol and Alcoholism, 54(2), 131–138. https://doi.org/10.1093/alcalc/agy085

Aims: This study aimed to describe healthcare utilisation, morbidities and monitoring of alcohol use in patients prior to a diagnosis of alcoholic psychosis in order to inform the early identification of patients at risk.

Method: Using linked gene... Read More about Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis.

Keeping active: maintenance of physical activity after exercise programs for older adults (2018)
Journal Article
Kendrick, D., Orton, E., Lafond, N., Audsley, S., Maula, A., Morris, R., Vedhara, K., & Iliffe, S. (2018). Keeping active: maintenance of physical activity after exercise programs for older adults. Public Health, 164, 118-127. https://doi.org/10.1016/j.puhe.2018.08.003

Objectives: To explore factors associated with maintenance of moderate-to-vigorous physical activity (MVPA) in community-dwelling adults aged ≥65 years after completing a 24-week exercise programme.
Study design: Cohort study nested within a randomi... Read More about Keeping active: maintenance of physical activity after exercise programs for older adults.

Poisoning substances taken by young people: a population-based cohort study (2018)
Journal Article
Tyrrell, E. G., Kendrick, D., Sayal, K., & Orton, E. (2018). Poisoning substances taken by young people: a population-based cohort study. British Journal of General Practice, 68(675), e703-e710. https://doi.org/10.3399/bjgp18X698897

Background: Globally, poisonings account for most medically-attended self-harm. Recent data on poisoning substances are lacking, but needed to inform self-harm prevention.
Aim: To assess poisoning substance patterns and trends among 10-24 year olds... Read More about Poisoning substances taken by young people: a population-based cohort study.

A logic model for the implementation of a falls management exercise programme (2018)
Book
Timblin, C., Audsley, S., Carpenter, H., Coupland, C., Gladman, J., Kendrick, D., Lafond, N., Logan, P., Orton, E., Skelton, D. A., Timmons, S., & Ward, D. (2018). A logic model for the implementation of a falls management exercise programme. East Midlands Research into Ageing Network (EMRAN)

PHysical activity Implementation Study In Community-dwelling AduLts (PHISICAL): study protocol (2018)
Journal Article
Carpenter, H., Audsley, S., Coupland, C., Gladman, J. R., Kendrick, D., Lafond, N., Logan, P., Skelton, D. A., Timblin, C., Timmons, S., Ward, D., & Orton, E. (in press). PHysical activity Implementation Study In Community-dwelling AduLts (PHISICAL): study protocol. Injury Prevention, https://doi.org/10.1136/injuryprev-2017-042627

Background: Falls in older people are a leading causes of unintentional injury. Due to an ageing population, injuries are likely to increase unless more is done to reduce older people’s falls risk. In clinical trials, the Falls Management Exercise (F... Read More about PHysical activity Implementation Study In Community-dwelling AduLts (PHISICAL): study protocol.

Alcohol Misuse and Injury Outcomes in Young People Aged 10–24 (2017)
Journal Article
Lester, L., Baker, R., Coupland, C., & Orton, E. (2018). Alcohol Misuse and Injury Outcomes in Young People Aged 10–24. Journal of Adolescent Health, 62(4), 450-456. https://doi.org/10.1016/j.jadohealth.2017.10.003

Purpose: The burden of alcohol-attributable disease is a global problem. Young people often present to emergency health-care services with alcohol intoxication but little is known about how best to intervene at that point to improve future health out... Read More about Alcohol Misuse and Injury Outcomes in Young People Aged 10–24.

Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial (2017)
Journal Article
Hay, A. D., Little, P., Harnden, A., Thompson, M., Wang, K., Kendrick, D., Orton, E., Brookes, S. T., Young, G. J., May, M., Hollinghurst, S., Carroll, F. E., Downing, H., Timmins, D., Lafond, N., El-Gohary, M., & Moore, M. (2017). Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial. Journal of the American Medical Association, 318(8), 721-730. https://doi.org/10.1001/jama.2017.10572

© 2017 American Medical Association. All rights reserved. IMPORTANCE: Acute lower respiratory tract infection is common and often treated inappropriately in primary care with antibiotics. Corticosteroids are increasingly used but without sufficient e... Read More about Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial.

Venous thromboembolism in adults screened for Sickle Cell Trait: a population based cohort study with nested case-control analysis (2017)
Journal Article
Little, I., Vinogradova, Y., Orton, E., Kai, J., & Qureshi, N. (2017). Venous thromboembolism in adults screened for Sickle Cell Trait: a population based cohort study with nested case-control analysis. BMJ Open, 7(3), Article e012665. https://doi.org/10.1136/bmjopen-2016-012665

Objective: To determine whether sickle cell carriers (‘sickle cell trait’) have an increased risk of venous thromboembolism (VTE).


Design: Cohort study with nested case-control analysis.
Setting: General population with data from 609 UK gener... Read More about Venous thromboembolism in adults screened for Sickle Cell Trait: a population based cohort study with nested case-control analysis.

Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England (2017)
Journal Article
Baker, R., Kendrick, D., Tata, L. J., & Orton, E. (2017). Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England. Injury Prevention, 23(6), 396-402. https://doi.org/10.1136/injuryprev-2016-042294

Background: Maternal depression is common and associated with several child health outcomes. The impact on childhood injuries is underexplored, with existing studies relying on maternal reporting of injury occurrences. Using population healthcare dat... Read More about Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England.

School-based education programmes for the prevention of unintentional injuries in children and young people. (2016)
Journal Article
Orton, E., Whitehead, J., Mhizha-Murira, J. R., Clarkson, M., Watson, M. C., Mulvaney, C. A., Staniforth, J. U., & Bhuchar, M. (2016). School-based education programmes for the prevention of unintentional injuries in children and young people. Cochrane Database of Systematic Reviews, 12(CD0102), https://doi.org/10.1002/14651858.CD010246.pub2

Background: Unintentional injuries are the leading cause of death in children aged four to 18 years and are a major cause of ill health. The school setting offers the opportunity to deliver preventive interventions to a large number of children and h... Read More about School-based education programmes for the prevention of unintentional injuries in children and young people..

Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study (2016)
Journal Article
Tyrrell, E. G., Orton, E., Sayal, K., Baker, R., & Kendrick, D. (2017). Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health, 39(2), Article e1-e9. https://doi.org/10.1093/pubmed/fdw075

Background Accurate and up to date data on changes in poisoning incidence among young people are lacking. Recent linkage of UK primary care, hospital and mortality data allows these to be quantified to inform service delivery.

Methods An open coh... Read More about Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study.

Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England (2016)
Journal Article
Baker, R., Tata, L. J., Kendrick, D., Burch, T., Kennedy, M., & Orton, E. (2016). Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England. Burns, 42(7), 1609-1616. https://doi.org/10.1016/j.burns.2016.05.007

Objective: To describe patterns in thermal injury incidence and hospitalisations by age, sex, calendar year and socioeconomic status among 0-4 year olds in England for the period 1998-2013.

Participants: 708,050 children with linked primary care a... Read More about Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England.

Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data (2016)
Journal Article
Baker, R., Orton, E., Tata, L. J., & Kendrick, D. (2016). Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data. European Journal of Public Health, 26(6), 940-946. https://doi.org/10.1093/eurpub/ckw064

Background:
Understanding patterns of injury in England is challenging due to a lack of national injury surveillance data. Through recent linkage of a large primary care research database to hospitalization and mortality data, we describe the epide... Read More about Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data.

Changes in poisonings among adolescents in the UK between 1992 and 2012: a population based cohort study (2016)
Journal Article
Tyrrell, E. G., Orton, E., & Tata, L. J. (2016). Changes in poisonings among adolescents in the UK between 1992 and 2012: a population based cohort study. Injury Prevention, 22(6), 400-406. https://doi.org/10.1136/injuryprev-2015-041901

Background: Poisonings are a common cause of morbidity and mortality among adolescents. Yet surveillance data indicating current incidence rates (IRs) and time trends are lacking, making policy development and service planning difficult. We utilised... Read More about Changes in poisonings among adolescents in the UK between 1992 and 2012: a population based cohort study.

Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study (2015)
Journal Article
Otete, H. E., Orton, E., Fleming, K. M., & West, J. (2016). Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study. Liver International, 36(4), 538-546. https://doi.org/10.1111/liv.13002

BACKGROUND & AIMS:
Cirrhosis because of alcohol could be avoided if drinking behaviour could be altered earlier in the disease course. Our aim was to quantify the burden of morbidities in patients prior to alcoholic cirrhosis diagnosis, as this may... Read More about Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study.