All Outputs (7)

Neither small adults nor big children: Doing better for TYAs with brain tumors (2025)
Journal Article
Ritzmann, T. A., Hodgkinson, R., & Shanmugavadivel, S. (2025). Neither small adults nor big children: Doing better for TYAs with brain tumors. Clinical Cancer Research, https://doi.org/10.1158/1078-0432.CCR-25-1007

A recent article presents a molecular analysis of High-Grade Gliomas in teenagers and young adults (TYAs). To maximise the benefit of this advancing knowledge we must address the basics. Here, we highlight the challenge of lengthy diagnostic interval... Read More about Neither small adults nor big children: Doing better for TYAs with brain tumors.

Quantifying diagnostic intervals and routes to diagnosis for children and young people with cancer in the UK (Childhood Cancer Diagnosis study, CCD): a population-based observational study (2025)
Journal Article
Shanmugavadivel, D., Liu, J.-F., Ritzmann, T. A., Ball-Gamble, A., Polanco, A., Ranasinghe, N., Vedhara, K., Ojha, S., & Walker, D. (2025). Quantifying diagnostic intervals and routes to diagnosis for children and young people with cancer in the UK (Childhood Cancer Diagnosis study, CCD): a population-based observational study. Lancet Regional Health – Europe, Article 101329. https://doi.org/10.1016/j.lanepe.2025.101329

Background: Childhood cancer is a global disease burden, with early diagnosis a priority. We quantified diagnostic intervals and referral routes for children and young people (CYP 0–18 years) diagnosed with cancer in the UK. Methods: All CYP diagnose... Read More about Quantifying diagnostic intervals and routes to diagnosis for children and young people with cancer in the UK (Childhood Cancer Diagnosis study, CCD): a population-based observational study.

A review calling for research directed at early detection of childhood cancers: The clinical, scientific, and economic arguments for population screening and surveillance (2024)
Journal Article
Apps, J., Ritzmann, T. A., Liu, J., Shanmugavadivel, D., Halsey, C., Pritchard Jones, K., Atun, R., Oliver, K., Vedhara, K., Ball-Gamble, A., Ranasinghe, N., Polanco, A., Adamski, J., Green, A. L., & Walker, D. A. (2024). A review calling for research directed at early detection of childhood cancers: The clinical, scientific, and economic arguments for population screening and surveillance. European Journal of Cancer, 4, Article 100191. https://doi.org/10.1016/j.ejcped.2024.100191

Childhood cancers are increasingly recognised as disorders of tissue growth and development, through early life into adulthood. A rising proportion are currently considered to be related to a familial predisposition or associated with identified gene... Read More about A review calling for research directed at early detection of childhood cancers: The clinical, scientific, and economic arguments for population screening and surveillance.

Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’ (2023)
Journal Article
Shanmugavadivel, D., Liu, J.-F., Ball-Gamble, A., Polanco, A., Vedhara, K., Nathan, P., Walker, D., & Ojha, S. (2023). Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’. British Journal of General Practice, 73(733), 377-379. https://doi.org/10.3399/bjgp23x734673

In 2018, the World Health Organization declared childhood cancer as a global disease burden, launching a Global Initiative to improve survival to 60% worldwide by 2030. If achieved, it is estimated that an extra 1 million children’s lives will be sav... Read More about Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’.

Assessing and investigating children with suspected bone and abdominal tumours: an e-Delphi consensus process (2023)
Journal Article
Shanmugavadivel, D., Liu, J. F., Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2023). Assessing and investigating children with suspected bone and abdominal tumours: an e-Delphi consensus process. BMJ Paediatrics Open, 7, Article e001771. https://doi.org/10.1136/bmjpo-2022-001771

Background The incidence of childhood cancer has risen by 15% since the 1990s. Early diagnosis is key to optimising outcomes, however diagnostic delays are widely reported. Presenting symptoms are often non-specific causing a diagnostic dilemma for c... Read More about Assessing and investigating children with suspected bone and abdominal tumours: an e-Delphi consensus process.

The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer (2022)
Journal Article
Shanmugavadivel, D., Liu, J.-F., Ball-Gamble, A., Polanco, A., Vedhara, K., Walker, D., & Ojha, S. (2022). The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer. BMJ Open, 12(2), Article e058744. https://doi.org/10.1136/bmjopen-2021-058744

Introduction: Childhood cancer is diagnosed in 400 000 children and young people (CYP) aged 0–19 years worldwide annually. In the UK, a child’s cumulative cancer risk increases from 1 in 4690 from birth to aged 1, to 1 in 470 by age 15. Once diagnose... Read More about The Childhood Cancer Diagnosis (CCD) Study: a UK observational study to describe referral pathways and quantify diagnostic intervals in children and young people with cancer.

Multicentre service evaluation of presentation of newly diagnosed cancers and type 1 diabetes in children in the UK during the COVID-19 pandemic (2021)
Journal Article
Williams, G., McLean, R., Liu, J. F., Ritzmann, T. A., Dandapani, M., Shanmugavadivel, D., Sachdev, P., Brougham, M., Mitchell, R. T., Conway, N. T., Law, J., Cunnington, A., Ogunnaike, G., Brougham, K., Bayman, E., & Walker, D. (2021). Multicentre service evaluation of presentation of newly diagnosed cancers and type 1 diabetes in children in the UK during the COVID-19 pandemic. BMJ Paediatrics Open, 5(1), Article e001078. https://doi.org/10.1136/bmjpo-2021-001078

Background The COVID-19 pandemic led to changes in patterns of presentation to emergency departments. Child health professionals were concerned that this could contribute to the delayed diagnosis of life-threatening conditions, including childhood ca... Read More about Multicentre service evaluation of presentation of newly diagnosed cancers and type 1 diabetes in children in the UK during the COVID-19 pandemic.