All Outputs (4)

Alcohol Triggers the Accumulation of Oxidatively Damaged Proteins in Neuronal Cells and Tissues (2024)
Journal Article
Mudyanselage, A. W., Wijamunige, B. C., Kocoń, A., Turner, R., McLean, D., Morentin, B., Callado, L. F., & Carter, W. G. (2024). Alcohol Triggers the Accumulation of Oxidatively Damaged Proteins in Neuronal Cells and Tissues. Antioxidants, 13(5), Article 580. https://doi.org/10.3390/antiox13050580

Alcohol is toxic to neurons and can trigger alcohol-related brain damage, neuronal loss, and cognitive decline. Neuronal cells may be vulnerable to alcohol toxicity and damage from oxidative stress after differentiation. To consider this further, the... Read More about Alcohol Triggers the Accumulation of Oxidatively Damaged Proteins in Neuronal Cells and Tissues.

Venatorbacter cucullus gen. nov sp. nov a novel bacterial predator (2021)
Journal Article
Saeedi, A., Cummings, N. J., McLean, D., Connerton, I. F., & Connerton, P. L. (2021). Venatorbacter cucullus gen. nov sp. nov a novel bacterial predator. Scientific Reports, 11, Article 21393. https://doi.org/10.1038/s41598-021-00865-8

A novel Gram-stain negative, aerobic, halotolerant, motile, rod-shaped, predatory bacterium ASxL5T, was isolated from a bovine slurry tank in Nottinghamshire, UK using Campylobacter hyointestinalis as prey. Other Campylobacter species and members of... Read More about Venatorbacter cucullus gen. nov sp. nov a novel bacterial predator.

Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging (2021)
Journal Article
Martinez De La Cruz, B., Markus, R., Malla, S., Haig, M. I., Gell, C., Sang, F., Bellows, E., Sherif, M. A., McLean, D., Lourdusamy, A., Self, T., Bodi, Z., Smith, S., Fay, M., Macdonald, I. A., Fray, R., & Knight, H. M. (2021). Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging. Molecular Psychiatry, 26(12), 7141-7153. https://doi.org/10.1038/s41380-021-01282-z

Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis has previously been proposed to explain how mRNAs are available at specific activated synapse... Read More about Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging.

A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli (2019)
Other
Cogger-Ward, R., Collins, A., McLean, D., Dehinsilu, J., & Huett, A. (2019). A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli

Adherent Invasive Escherichia coli (AIEC) is a non-diarrhoeagenic intestinal E. coli pathotype associated with Crohn’s Disease. AIEC pathogenesis is characterised by biofilm formation, adhesion to and invasion of intestinal epithelial cells, and intr... Read More about A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli.