Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data

Baker, Ruth; Orton, Elizabeth; Tata, Laila J.; Kendrick, Denise

doi:10.1093/eurpub/ckw064

Economic evaluation of the OSAC randomised controlled trial: Oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care (2020)
Journal Article
Carroll, F. E., Moure-Fernandez, A., Hollinghurst, S., Downing, H., Young, G., Brookes, S., …Hay, A. D. (2020). Economic evaluation of the OSAC randomised controlled trial: Oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care. BMJ Open, 10(2), Article e033567. https://doi.org/10.1136/bmjopen-2019-033567

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. Objective To estimate the costs and outcomes associated with treating non-asthmatic adults (nor suffering from other lung-disease) presenting to primary care wit... Read More about Economic evaluation of the OSAC randomised controlled trial: Oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care.

Understanding pathways to social inequalities in childhood unintentional injuries: findings from the UK Millennium Cohort Study (2019)
Journal Article
Campbell, M., Lai, E. T., Pearce, A., Orton, E., Kendrick, D., Wickham, S., & Taylor-Robinson, D. C. (2019). Understanding pathways to social inequalities in childhood unintentional injuries: findings from the UK Millennium Cohort Study. BMC Pediatrics, 19, Article 150. https://doi.org/10.1186/s12887-019-1514-7

Background: Childhood unintentional injuries (UI) are common but continue to happen more often to children living in less advantaged socioeconomic circumstances (SEC). Our aim was to explore how early life factors mediate the association between SEC... Read More about Understanding pathways to social inequalities in childhood unintentional injuries: findings from the UK Millennium Cohort Study.

Keeping active: maintenance of physical activity after exercise programs for older adults (2018)
Journal Article
Kendrick, D., Orton, E., Lafond, N., Audsley, S., Maula, A., Morris, R., …Iliffe, S. (2018). Keeping active: maintenance of physical activity after exercise programs for older adults. Public Health, 164, 118-127. https://doi.org/10.1016/j.puhe.2018.08.003

Objectives: To explore factors associated with maintenance of moderate-to-vigorous physical activity (MVPA) in community-dwelling adults aged ≥65 years after completing a 24-week exercise programme. Study design: Cohort study nested within a randomi... Read More about Keeping active: maintenance of physical activity after exercise programs for older adults.

Poisoning substances taken by young people: a population-based cohort study (2018)
Journal Article
Tyrrell, E. G., Kendrick, D., Sayal, K., & Orton, E. (2018). Poisoning substances taken by young people: a population-based cohort study. British Journal of General Practice, 68(675), e703-e710. https://doi.org/10.3399/bjgp18X698897

Background: Globally, poisonings account for most medically-attended self-harm. Recent data on poisoning substances are lacking, but needed to inform self-harm prevention. Aim: To assess poisoning substance patterns and trends among 10-24 year olds... Read More about Poisoning substances taken by young people: a population-based cohort study.

Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study (2018)
Journal Article
Kendrick, D., Baker, R., Hill, T., Beckett, K., Coupland, C., Kellezi, B., …Morriss, R. (2018). Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study. Journal of Psychosomatic Research, 112, 15-24. https://doi.org/10.1016/j.jpsychores.2018.06.008

Objective: To quantify psychological morbidity and identify baseline factors associated with depression, anxiety and post-traumatic distress symptoms up to 12 months post-injury. Methods: Multicentre cohort study of 668 adults, aged 16 to 70,... Read More about Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study.

Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial (2017)
Journal Article
Hay, A. D., Little, P., Harnden, A., Thompson, M., Wang, K., Kendrick, D., …Moore, M. (2017). Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial. Journal of the American Medical Association, 318(8), 721-730. https://doi.org/10.1001/jama.2017.10572

© 2017 American Medical Association. All rights reserved. IMPORTANCE: Acute lower respiratory tract infection is common and often treated inappropriately in primary care with antibiotics. Corticosteroids are increasingly used but without sufficient e... Read More about Effect of oral prednisolone on symptom duration and severity in nonasthmatic adults with acute lower respiratory tract infection: a randomized clinical trial.

Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives (2017)
Journal Article
Kendrick, D., Ablewhite, J., Achana, F., Benford, P., Clacy, R., Coffey, F., …Zou, K. (2017). Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives. Programme Grants for Applied Research, 5(14), https://doi.org/10.3310/pgfar05140

Background: Unintentional injuries among 0- to 4-year-olds are a major public health problem incurring substantial NHS, individual and societal costs. However, evidence on the effectiveness and cost-effectiveness of preventative interventions is lack... Read More about Keeping children safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives.

Psychological morbidity and return to work after injury: multicentre cohort study (2017)
Journal Article
Kendrick, D., Dhiman, P., Kellezi, B., Coupland, C., Whitehead, J., Beckett, K., …Morriss, R. (in press). Psychological morbidity and return to work after injury: multicentre cohort study. British Journal of General Practice, https://doi.org/10.3399/bjgp17X691673

Background: The benefits of work for physical, psychological and financial wellbeing are well documented. Return to work (RTW) after unintentional injury is often delayed, and psychological morbidity may contribute to this delay. The impact of psycho... Read More about Psychological morbidity and return to work after injury: multicentre cohort study.

Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial (2017)
Journal Article
Deave, T., Hawkins, A., Kumar, A., Hayes, M., Cooper, N., Watson, M., …Kendrick, D. (2017). Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial. PLoS ONE, 12(3), Article e0172584. https://doi.org/10.1371/journal.pone.0172584

Background: Many developed countries have high mortality rates for fire-related deaths in children aged 0–14 years with steep social gradients. Evidence-based interventions to promote fire safety practices exist, but the impact of implementing a rang... Read More about Evaluating implementation of a fire-prevention injury prevention briefing in children's centres: cluster randomised controlled trial.

Use of conspicuity aids by cyclists and risk of crashes involving other road users: population based case-control study (2017)
Journal Article
Miller, P., Kendrick, D., Coupland, C., & Coffey, F. (in press). Use of conspicuity aids by cyclists and risk of crashes involving other road users: population based case-control study. Journal of Transport and Health, 7(A), https://doi.org/10.1016/j.jth.2017.03.008

Background: Cycling can improve health and well-being by reducing inactivity. Concern about collision crashes may be a barrier to participation since collision crashes can lead to significant mortality and morbidity. The conspicuity of cyclists may b... Read More about Use of conspicuity aids by cyclists and risk of crashes involving other road users: population based case-control study.

Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial (2017)
Journal Article
Sullivan, F., Farmer, E., Mair, F. S., Treweek, S., Kendrick, D., Jackson, C., …Schembri, S. (2017). Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial. BMC Cancer, 17(1), https://doi.org/10.1186/s12885-017-3175-y

Background: Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The EarlyCDT®-Lung Test detects autoantibodies to abnormal cell surface proteins in the ear... Read More about Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial.

Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England (2017)
Journal Article
Baker, R., Kendrick, D., Tata, L. J., & Orton, E. (2017). Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England. Injury Prevention, 23(6), 396-402. https://doi.org/10.1136/injuryprev-2016-042294

Background: Maternal depression is common and associated with several child health outcomes. The impact on childhood injuries is underexplored, with existing studies relying on maternal reporting of injury occurrences. Using population healthcare dat... Read More about Association between maternal depression and anxiety episodes and rates of childhood injuries: a cohort study from England.

Poison prevention practices and medically attended poisoning in young children: multicentre case-control study (2016)
Journal Article
Kendrick, D., Majsak-Newman, G., Benford, P., Coupland, C., Timblin, C., Hayes, M., …Reading, R. (2017). Poison prevention practices and medically attended poisoning in young children: multicentre case-control study. Injury Prevention, 23(2), 93-101. https://doi.org/10.1136/injuryprev-2015-041828

Introduction Childhood poisonings are common, placing a substantial burden on health services. Case-control studies have found inconsistent evidence about modifiable risk factors for poisonings amongst 0-4 year olds. This study quantifies associat... Read More about Poison prevention practices and medically attended poisoning in young children: multicentre case-control study.

The impact of psychological factors on recovery from injury: a multicentre cohort study (2016)
Journal Article
Kellezi, B., Coupland, C., Morriss, R., Beckett, K., Joseph, S., Barnes, J., …Kendrick, D. (2016). The impact of psychological factors on recovery from injury: a multicentre cohort study. Social Psychiatry and Psychiatric Epidemiology, 52(7), https://doi.org/10.1007/s00127-016-1299-z

Purpose Unintentional injuries have a significant long-term health impact in working age adults. Depression, anxiety and post-traumatic stress disorder are common post-injury, but their impact on self-reported recovery has not been investigated in g... Read More about The impact of psychological factors on recovery from injury: a multicentre cohort study.

Psychological morbidity and health related quality of life after injury: multicentre cohort study (2016)
Journal Article
Kendrick, D., Kellezi, B., Coupland, C., Maula, A., Beckett, K., Morriss, R. K., …Christie, N. (2017). Psychological morbidity and health related quality of life after injury: multicentre cohort study. Quality of Life Research, 26(5), 1233-1250. https://doi.org/10.1007/s11136-016-1439-7

Purpose: To demonstrate the impact of psychological morbidity one month post-injury on subsequent post-injury quality of life (HRQoL) in a general injury population in the UK to inform development of trauma care and rehabilitation services. Method... Read More about Psychological morbidity and health related quality of life after injury: multicentre cohort study.

Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study (2016)
Journal Article
Tyrrell, E. G., Orton, E., Sayal, K., Baker, R., & Kendrick, D. (2017). Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health, 39(2), Article e1-e9. https://doi.org/10.1093/pubmed/fdw075

Background Accurate and up to date data on changes in poisoning incidence among young people are lacking. Recent linkage of UK primary care, hospital and mortality data allows these to be quantified to inform service delivery. Methods An open coh... Read More about Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study.

A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children (2016)
Journal Article
Achana, F., Sutton, A. J., Kendrick, D., Hayes, M., Jones, D. R., Hubbard, S. J., & Cooper, N. J. (2016). A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children. BMC Public Health, 16, Article 705. https://doi.org/10.1186/s12889-016-3334-0

Background: Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-e... Read More about A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children.

Reducing falls among older people in general practice: the ProAct65+ exercise intervention trial (2016)
Journal Article
Gawler, S., Skelton, D. A., Dinan-Young, S., Masud, T., Morris, R. W., Griffin, M., …Iliffe, S. (2016). Reducing falls among older people in general practice: the ProAct65+ exercise intervention trial. Archives of Gerontology and Geriatrics, 67, https://doi.org/10.1016/j.archger.2016.06.019

Background: Falls are common in the older UK population and associated costs to the NHS are high. Systematic reviews suggest that home exercise and group-based exercise interventions, which focus on progressively challenging balance and increasing st... Read More about Reducing falls among older people in general practice: the ProAct65+ exercise intervention trial.

Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England (2016)
Journal Article
Baker, R., Tata, L. J., Kendrick, D., Burch, T., Kennedy, M., & Orton, E. (2016). Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England. Burns, 42(7), 1609-1616. https://doi.org/10.1016/j.burns.2016.05.007

Objective: To describe patterns in thermal injury incidence and hospitalisations by age, sex, calendar year and socioeconomic status among 0-4 year olds in England for the period 1998-2013. Participants: 708,050 children with linked primary care a... Read More about Differing patterns in thermal injury incidence and hospitalisations among 0–4 year old children from England.

Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data (2016)
Journal Article
Baker, R., Orton, E., Tata, L. J., & Kendrick, D. (2016). Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data. European Journal of Public Health, 26(6), 940-946. https://doi.org/10.1093/eurpub/ckw064

Background: Understanding patterns of injury in England is challenging due to a lack of national injury surveillance data. Through recent linkage of a large primary care research database to hospitalization and mortality data, we describe the epide... Read More about Epidemiology of poisonings, fractures and burns among 0–24 year olds in England using linked health and mortality data.

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