All Outputs (49)

Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges (2024)
Journal Article
Hall, C. L., Gómez Bergin, A. D., & Rennick-Egglestone, S. (in press). Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges. Journal of Medical Internet Research, https://doi.org/10.2196/58939

Digital mental health interventions are routinely integrated into mental health services internationally, and can contribute to the reduction of the global mental health treatment gap that has been identified by the World Health Organisation. Researc... Read More about Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges.

Experience of CBT in adults with ADHD: a mixed methods study (2024)
Journal Article
William, S., Horrocks, M., Richmond, J., Hall, C. L., & French, B. (2024). Experience of CBT in adults with ADHD: a mixed methods study. Frontiers in Psychiatry, 15, Article 1341624. https://doi.org/10.3389/fpsyt.2024.1341624

Introduction: The National Institute for Health and Care Excellence (NICE) recommends Cognitive Behavioural therapy (CBT) as the psychotherapeutic treatment of choice for adults with Attention Deficit Hyperactivity Disorder (ADHD) in the UK. However,... Read More about Experience of CBT in adults with ADHD: a mixed methods study.

Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context (2024)
Journal Article
Taher, R., Bhanushali, P., Allan, S., Alvarez-Jimenez, M., Bolton, H., Dennison, L., …Yiend, J. (2024). Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context. BJPsych Open, 10(4), Article e126. https://doi.org/10.1192/bjo.2024.713

Background Digital Mental Health Interventions (DMHIs) that meet the definition of a medical device are regulated by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK. The MHRA uses procedures that were originally developed fo... Read More about Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context.

The impacts associated with having ADHD: an umbrella review (2024)
Journal Article
French, B., Nalbant, G., Wright, H., Sayal, K., Daley, D., Groom, M. J., …Hall, C. L. (2024). The impacts associated with having ADHD: an umbrella review. Frontiers in Psychiatry, 15, Article 1343314. https://doi.org/10.3389/fpsyt.2024.1343314

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) affects up to 5% of the population and is characterised by symptoms of impulsivity, hyperactivity and inattention. These symptoms are significantly impairing and carry additional risks for... Read More about The impacts associated with having ADHD: an umbrella review.

Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial (2024)
Journal Article
Andrén, P., Sampaio, F., Ringberg, H., Wachtmeister, V., Warnström, M., Isomura, K., …Mataix-Cols, D. (2024). Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial. JAMA Network Open, 7(5), Article e248468. https://doi.org/10.1001/jamanetworkopen.2024.8468

Importance: Behavior therapy is a recommended intervention for Tourette syndrome (TS) and chronic tic disorder (CTD), but availability is limited and long-term effects are uncertain. Objective: To investigate the long-term efficacy and cost-effec... Read More about Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial.

Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation (2023)
Journal Article
Hollis, C., Hall, C. L., Khan, K., Le Novere, M., Marston, L., Jones, R., …Murphy, T. (2023). Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation. Health Technology Assessment, 27(18), 1-120. https://doi.org/10.3310/cpms3211

Background: Behavioural therapy for tics is difficult to access, and little is known about its effectiveness when delivered online. Objective: To investigate the clinical and cost-effectiveness of an online-delivered, therapist and parent-... Read More about Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation.

Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis (2023)
Journal Article
Bellato, A., Hall, C. L., Groom, M. J., Simonoff, E., Thapar, A., Hollis, C., & Cortese, S. (2024). Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis. Journal of Child Psychology and Psychiatry, 65(6), 845-861. https://doi.org/10.1111/jcpp.13901

Background Several computerised cognitive tests (e.g. continuous performance test) have been developed to support the clinical assessment of attention-deficit/hyperactivity disorder (ADHD). Here, we appraised the evidence-base underpinning the use o... Read More about Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis.

The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know? (2023)
Journal Article
Hall, C. L., Bellato, A., Kirk, J. D., & Hollis, C. (2023). The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know?. Paediatrics and Child Health, 33(9), 259-264. https://doi.org/10.1016/j.paed.2023.06.006

The assessment of Attention-Deficit/Hyperactivity Disorder (ADHD) typically relies on subjective observer reports from parents, teachers, or the young person, combined with clinical observation and history. Children and young people often experience... Read More about The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know?.

Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial (2023)
Journal Article
Hollis, C., Hall, C. L., Khan, K., Jones, R., Marston, L., Le Novere, M., …Murphy, T. (2023). Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial. Journal of Child Psychology and Psychiatry, 64(6), 941-951. https://doi.org/10.1111/jcpp.13756

Background: Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 a... Read More about Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial.

Understanding the Impact of Home Confinement on Children and Young People with ADHD and ASD During the COVID-19 Pandemic (2023)
Journal Article
Hall, C. L., Partlett, C., Valentine, A. Z., Pearcey, S., & Sayal, K. (2023). Understanding the Impact of Home Confinement on Children and Young People with ADHD and ASD During the COVID-19 Pandemic. Child Psychiatry and Human Development, https://doi.org/10.1007/s10578-022-01490-w

To understand whether the mental health of children and young people (CYP) with and without attention-deficit/hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD) were differentially affected by COVID-19. We analysed data (n = 6507) fr... Read More about Understanding the Impact of Home Confinement on Children and Young People with ADHD and ASD During the COVID-19 Pandemic.

Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial (2022)
Journal Article
Chitsabesan, P., Hall, C. L., Carter, L., Reeves, M., Mohammed, V., Beresford, B., …Lennox, C. (2022). Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial. BMJ Open, 12(12), Article e064951. https://doi.org/10.1136/bmjopen-2022-064951

Objectives: QbTest has been shown to improve time to decision/diagnosis for young people with Attention Deficit Hyperactivity Disorder (ADHD). The aim was to assess feasibility of QbTest for young people in prison. Design: Single centre fe... Read More about Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial.

Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome: A Randomized Clinical Trial (2022)
Journal Article
Andrén, P., Holmsved, M., Ringberg, H., Wachtmeister, V., Isomura, K., Aspvall, K., …Mataix-Cols, D. (2022). Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome: A Randomized Clinical Trial. JAMA Network Open, 5(8), Article e2225614. https://doi.org/10.1001/jamanetworkopen.2022.25614

Importance: The availability of behavior therapy for individuals with Tourette syndrome (TS) and chronic tic disorder (CTD) is limited. Objective: To determine the efficacy and cost-effectiveness of internet-delivered exposure and response prevention... Read More about Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome: A Randomized Clinical Trial.

The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study (2022)
Journal Article
Hall, C. L., Marston, L., Khan, K., Brown, B. J., Sanderson, C., Andrén, P., …Murphy, T. (2023). The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study. Child Psychiatry and Human Development, 54(6), 1499–1509. https://doi.org/10.1007/s10578-022-01348-1

To understand how children and young people with tic disorders were affected by COVID-19, we compared pre and during pandemic scores on the Yale Global Tic Severity Scale (YGTSS). Participants were young people (N = 112; male:78%; 9–17 years) randomi... Read More about The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study.

Treatment adherence might be the key to online Exposure and Response Prevention for paediatric tics – Authors' reply (2022)
Journal Article
Hollis, C., Hall, C. L., Marston, L., & ORBIT Trial Team. (2022). Treatment adherence might be the key to online Exposure and Response Prevention for paediatric tics – Authors' reply. Lancet Psychiatry, 9(2), 106-107. https://doi.org/10.1016/S2215-0366%2821%2900503-4

We thank Qianzhi Wang and colleagues for their endorsement of the ORBIT trial1, 2 and for acknowledging the importance of the findings. We are grateful for the opportunity to clarify the issue of adherence within the trial, which we believe to be a... Read More about Treatment adherence might be the key to online Exposure and Response Prevention for paediatric tics – Authors' reply.

Efficacy and cost-effectiveness of therapist-guided internet-delivered behaviour therapy for children and adolescents with Tourette syndrome: study protocol for a single-blind randomised controlled trial (2021)
Journal Article
Andrén, P., Fernández De La Cruz, L., Isomura, K., Lenhard, F., Hall, C. L., Davies, E. B., …Mataix-Cols, D. (2021). Efficacy and cost-effectiveness of therapist-guided internet-delivered behaviour therapy for children and adolescents with Tourette syndrome: study protocol for a single-blind randomised controlled trial. Trials, 22, Article 669. https://doi.org/10.1186/s13063-021-05592-z

Background Treatment guidelines recommend behaviour therapy (BT) for patients with Tourette syndrome (TS) and chronic tic disorder (CTD). However, BT is rarely accessible due to limited availability of trained therapists and long travel distances to... Read More about Efficacy and cost-effectiveness of therapist-guided internet-delivered behaviour therapy for children and adolescents with Tourette syndrome: study protocol for a single-blind randomised controlled trial.

Efficacy and cost-effectiveness of therapist-guided internet-delivered behaviour therapy for children and adolescents with Tourette syndrome: study protocol for a single-blind randomised controlled trial (2021)
Journal Article
Andrén, P., de la Cruz, L. F., Isomura, K., Lenhard, F., Hall, C. L., Davies, E. B., …Mataix-Cols, D. (2021). Efficacy and cost-effectiveness of therapist-guided internet-delivered behaviour therapy for children and adolescents with Tourette syndrome: study protocol for a single-blind randomised controlled trial. Trials, 22, Article 669. https://doi.org/10.1186/s13063-021-05592-z

Background: Treatment guidelines recommend behaviour therapy (BT) for patients with Tourette syndrome (TS) and chronic tic disorder (CTD). However, BT is rarely accessible due to limited availability of trained therapists and long travel distances to... Read More about Efficacy and cost-effectiveness of therapist-guided internet-delivered behaviour therapy for children and adolescents with Tourette syndrome: study protocol for a single-blind randomised controlled trial.

Therapist-supported online remote behavioural intervention for tics in children and adolescents in England (ORBIT): a multicentre, parallel group, single-blind, randomised controlled trial (2021)
Journal Article
Hollis, C., Hall, C. L., Jones, R., Marston, L., Novere, M. L., Hunter, R., …Murray, E. (2021). Therapist-supported online remote behavioural intervention for tics in children and adolescents in England (ORBIT): a multicentre, parallel group, single-blind, randomised controlled trial. Lancet Psychiatry, 8(10), 871-882. https://doi.org/10.1016/S2215-0366%2821%2900235-2

Background: Exposure and Response Prevention (ERP) is a form of behavioural therapy for tics; however, its effectiveness remains uncertain. We aimed to evaluate the effectiveness of internet-delivered, therapist-supported, and parent-assisted ERP for... Read More about Therapist-supported online remote behavioural intervention for tics in children and adolescents in England (ORBIT): a multicentre, parallel group, single-blind, randomised controlled trial.

Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., …Groom, M. J. (2021). Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 94. https://doi.org/10.1186/s40814-021-00830-2

The implementation of telehealth to assess, monitor and treat neurodevelopmental disorders: a systematic review (2021)
Journal Article
Valentine, A. Z., Hall, S. S., Young, E., Brown, B. J., Groom, M. J., Hollis, C., & Hall, C. L. (2021). The implementation of telehealth to assess, monitor and treat neurodevelopmental disorders: a systematic review. Journal of Medical Internet Research, 23(1), Article e22619. https://doi.org/10.2196/22619

Background: In response to COVID-19 there is increasing momentum behind the development and delivery of telehealth. To assess the anticipated exponential growth in telehealth it is important we accurately capture how telehealth was used in specific f... Read More about The implementation of telehealth to assess, monitor and treat neurodevelopmental disorders: a systematic review.

Opportunities and challenges of delivering digital clinical trials: lessons learned from a randomised controlled trial of an online behavioural intervention for children and young people (2020)
Journal Article
Hall, C. L., Sanderson, C., Brown, B. J., Andrén, P., Bennett, S., Chamberlain, L. R., …Murray, E. (2020). Opportunities and challenges of delivering digital clinical trials: lessons learned from a randomised controlled trial of an online behavioural intervention for children and young people. Trials, 21(1), Article 1011. https://doi.org/10.1186/s13063-020-04902-1

Background: Despite being the gold standard of research to determine effectiveness, randomised controlled trials (RCTs) often struggle with participant recruitment, engagement and retention. These issues may be exacerbated when recruiting vulnerable... Read More about Opportunities and challenges of delivering digital clinical trials: lessons learned from a randomised controlled trial of an online behavioural intervention for children and young people.