Prathiba Chitsabesan
Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial
Chitsabesan, Prathiba; Hall, Charlotte Lucy; Carter, Lesley-Anne; Reeves, Mindy; Mohammed, Vaseem; Beresford, Bryony; Young, Susan; Kraam, Abdullah; Trwose, Sally; Wilkinson-Cunningham, Lloyd; Lennox, Charlotte
Authors
CHARLOTTE HALL CHARLOTTE.HALL@NOTTINGHAM.AC.UK
Principal Research Fellow
Lesley-Anne Carter
Mindy Reeves
Vaseem Mohammed
Bryony Beresford
Susan Young
Abdullah Kraam
Sally Trwose
Lloyd Wilkinson-Cunningham
Charlotte Lennox
Abstract
Objectives:
QbTest has been shown to improve time to decision/diagnosis for young people with Attention Deficit Hyperactivity Disorder (ADHD). The aim was to assess feasibility of QbTest for young people in prison.
Design:
Single centre feasibility Randomised Controlled Trial (RCT), with 1:1 allocation. Concealed random allocation using an online pseudo-random list with random permuted blocks of varying sizes.
Setting: One Young Offenders Institution (YOI) in England.
Participants:
355 young people aged 15-18 years displaying possible symptoms of ADHD were assessed for eligibility, 69 were eligible to take part and 60 were randomised.
Intervention:
QbTest - a computer task measuring attention, activity, and impulsivity.
Main outcome measures:
Eligibility, recruitment and retention rates and acceptability of randomisation and trial participation.
Results:
Of the 355 young people assessed for eligibility, 69 were eligible, and 60 were randomised (n = 30 QbTest plus usual care; n = 30 usual care alone). The study achieved the specified recruitment target. Trial participation and randomisation were deemed acceptable by the majority of participants. 78% of young people were followed up at 3-months, but only 32% at 6-months, although this was also affected by COVID restrictions. Secondary outcomes were mixed. Participants including clinical staff were mostly supportive of the study and QbTest, however some young people found QbTest hard and there were issues with implementation of the ADHD care pathway. There were no serious adverse events secondary to the study or intervention and no one was withdrawn from the study due to an adverse event.
Conclusions:
With adaptations, a fully powered RCT may be achievable to evaluate the effectiveness of QbTest in the assessment of ADHD in the CYPSE, with time to decision (days) as the primary outcome measure. However, further programme developmental work is required to address some of the challenges highlighted prior to a larger trial.
Citation
Chitsabesan, P., Hall, C. L., Carter, L., Reeves, M., Mohammed, V., Beresford, B., …Lennox, C. (2022). Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial. BMJ Open, 12(12), Article e064951. https://doi.org/10.1136/bmjopen-2022-064951
Journal Article Type | Article |
---|---|
Acceptance Date | Nov 25, 2022 |
Online Publication Date | Dec 16, 2022 |
Publication Date | Dec 16, 2022 |
Deposit Date | Nov 28, 2022 |
Publicly Available Date | Dec 16, 2022 |
Journal | BMJ Open |
Electronic ISSN | 2044-6055 |
Publisher | BMJ Publishing Group |
Peer Reviewed | Peer Reviewed |
Volume | 12 |
Issue | 12 |
Article Number | e064951 |
DOI | https://doi.org/10.1136/bmjopen-2022-064951 |
Keywords | General Medicine |
Public URL | https://nottingham-repository.worktribe.com/output/14307149 |
Publisher URL | https://bmjopen.bmj.com/content/12/12/e064951 |
Additional Information | © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. |
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