All Outputs (3)

MBRS-21. EXTRACELLULAR VESICLES FROM METASTATIC MEDULLOBLASTOMA CELL LINES CARRY mRNAs KNOWN TO CORRELATE WITH METASTATIC DISEASE (2018)
Presentation / Conference Contribution
Jackson, H. K., Linke, F., Kerr, I. D., & Coyle, B. MBRS-21. EXTRACELLULAR VESICLES FROM METASTATIC MEDULLOBLASTOMA CELL LINES CARRY mRNAs KNOWN TO CORRELATE WITH METASTATIC DISEASE

Wilms' Tumor protein 1 and enzymatic oxidation of 5-methylcytosine in brain tumors: potential perspectives (2018)
Journal Article
Ramsawhook, A., Ruzov, A., & Coyle, B. (2018). Wilms' Tumor protein 1 and enzymatic oxidation of 5-methylcytosine in brain tumors: potential perspectives. Frontiers in Cell and Developmental Biology, 6, https://doi.org/10.3389/fcell.2018.00026

The patterns of 5-methylcytosine (5mC) and its oxidized derivatives, 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine (5caC) are reportedly altered in a range of cancers. Likewise, Wilms’ Tumor protein 1 (WT1), a transcription factor... Read More about Wilms' Tumor protein 1 and enzymatic oxidation of 5-methylcytosine in brain tumors: potential perspectives.

A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells (2018)
Journal Article
Ahmed, E. M., Bandopadhyay, G., Coyle, B., & Grabowska, A. M. (2018). A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells. Cellular Oncology, 41(3), https://doi.org/10.1007/s13402-018-0374-8

Purpose


Glioblastoma Multiforme (GBM) is the commonest brain tumour in adults. A population of cells, known as cancer stem cells (CSCs), is thought to mediate chemo/radiotherapy resistance. CD133 is a cell surface marker to identify and isolate... Read More about A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells.