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Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication (2025)
Journal Article
Romero, M., Luckett, J., Dubern, J.-F., Figueredo, G. P., Ison, E., Carabelli, A. M., Scurr, D. J., Hook, A. L., Kammerling, L., Da Silva, A. C., Xue, X., Blackburn, C., Carlier, A., Vasilevich, A., Sudarsanam, P. K., Vermeulen, S., Winkler, D. A., Ghaemmaghami, A. M., De Boer, J., Alexander, M. R., & Williams, P. (2025). Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication. Nature Communications, 16(1), Article 5295. https://doi.org/10.1038/s41467-025-60567-x

Bio-instructive materials that intrinsically inhibit biofilm formation have significant anti-biofouling potential in industrial and healthcare settings. Since bacterial surface attachment is sensitive to surface topography, we experimentally surveyed... Read More about Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication.

Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration (2020)
Journal Article
Vallieres, C., Hook, A. L., He, Y., Crucitti, V. C., Figueredo, G., Davies, C. R., Burroughs, L., Winkler, D. A., Wildman, R. D., Irvine, D. J., Alexander, M. R., & Avery, S. V. (2020). Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration. Science Advances, 6(23), Article eaba6574. https://doi.org/10.1126/sciadv.aba6574

© 2020 The Authors. Fungi have major, negative socioeconomic impacts, but control with bioactive agents is increasingly restricted, while resistance is growing. Here, we describe an alternative fungal control strategy via materials operating passivel... Read More about Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration.