All Outputs (27)

A minimally invasive optical trapping system to understand cellular interactions at onset of an immune response (2017)
Journal Article
Glass, D. G., McAlinden, N., Millington, O. R., & Wright, A. J. (2017). A minimally invasive optical trapping system to understand cellular interactions at onset of an immune response. PLoS ONE, 12(12), Article e0188581. https://doi.org/10.1371/journal.pone.0188581

T-cells and antigen presenting cells are an essential part of the adaptive immune response system and how they interact is crucial in how the body effectively fights infection or responds to vaccines. Much of the experimental work studying interactio... Read More about A minimally invasive optical trapping system to understand cellular interactions at onset of an immune response.

Engineering of hybrid photonic-plasmonic devices for enhanced light-matter interactions (2017)
Book Chapter
Mossayebi, M., Bellanca, G., Parini, A., Wright, A. J., & Larkins, E. C. (2017). Engineering of hybrid photonic-plasmonic devices for enhanced light-matter interactions. In A. Agrawal, T. Benson, R. De La Rue, & G. Wurtz (Eds.), Recent Trends in Computational Photonics (369-390). Springer. https://doi.org/10.1007/978-3-319-55438-9_13

In this chapter, we focus on the design and characteristics of a hybrid photonic-plasmonic nanoresonator using 3D finite-difference time-domain simulations. This structure is capable of localization of high intensity light in a subwavelength hotspot,... Read More about Engineering of hybrid photonic-plasmonic devices for enhanced light-matter interactions.

Surface-enhanced Raman scattering measurement from a lipid bilayer encapsulating a single decahedral nanoparticle mediated by an optical trap (2016)
Journal Article
Wright, A. J., Richens, J. L., Bramble, J., Cathcart, N., Kitaev, V., O'Shea, P., & Hudson, A. (in press). Surface-enhanced Raman scattering measurement from a lipid bilayer encapsulating a single decahedral nanoparticle mediated by an optical trap. Nanoscale, 8(36), https://doi.org/10.1039/C6NR05616D

We present a new technique for the study of model membranes on the length-scale of a single nanosized liposome. Silver decahedral nanoparticles have been encapsulated by a model unilamellar lipid bilayer creating nano-sized lipid vesicles. The metal... Read More about Surface-enhanced Raman scattering measurement from a lipid bilayer encapsulating a single decahedral nanoparticle mediated by an optical trap.

Investigating the use of a hybrid plasmonic-photonic nanoresonator for optical trapping using finite-difference time-domain method (2016)
Journal Article
Mossayebi, M., Wright, A., Parini, A., Somekh, M., Bellanca, G., & Larkins, E. (2016). Investigating the use of a hybrid plasmonic-photonic nanoresonator for optical trapping using finite-difference time-domain method. Optical and Quantum Electronics, 48(5), Article 275. https://doi.org/10.1007/s11082-016-0539-5

We investigate the use of a hybrid nanoresonator comprising a photonic crystal (PhC) cavity coupled to a plasmonic bowtie nanoantenna (BNA) for the optical trapping of nanoparticles in water. Using finite-difference time-domain simulations, we show t... Read More about Investigating the use of a hybrid plasmonic-photonic nanoresonator for optical trapping using finite-difference time-domain method.

Accurate position tracking of optically trapped live cells (2014)
Journal Article
McAlinden, N., Glass, D. G., Millington, O. R., & Wright, A. J. (2014). Accurate position tracking of optically trapped live cells. Biomedical Optics Express, 5(4), https://doi.org/10.1364/BOE.5.001026

Optical trapping is a powerful tool in Life Science research and is becoming common place in many microscopy laboratories and facilities. There is a growing need to directly trap the cells of interest rather than introduce beads to the sample that ca... Read More about Accurate position tracking of optically trapped live cells.

Strategies to overcome photobleaching in algorithm-based adaptive optics for nonlinearin-vivoimaging (2014)
Journal Article
Müllenbroich, M. C., McGhee, E. J., Wright, A. J., Anderson, K. I., & Mathieson, K. (2014). Strategies to overcome photobleaching in algorithm-based adaptive optics for nonlinearin-vivoimaging. Journal of Biomedical Optics, 19(1), Article 016021. https://doi.org/10.1117/1.JBO.19.1.016021

We have developed a nonlinear adaptive optics microscope utilizing a deformable membrane mirror (DMM) and demonstrated its use in compensating for system- and sample-induced aberrations. The optimum shape of the DMM was determined with a random searc... Read More about Strategies to overcome photobleaching in algorithm-based adaptive optics for nonlinearin-vivoimaging.

Investigating the microrheology of the vitreous humor using an optically trapped local probe (2013)
Journal Article
Watts, F., Tan, L. E., Wilson, C. G., Girkin, J. M., Tassieri, M., & Wright, A. J. (2013). Investigating the microrheology of the vitreous humor using an optically trapped local probe. Journal of Optics, 16(1), https://doi.org/10.1088/2040-8978/16/1/015301

We demonstrate that an optically trapped silica bead can be used as a local probe to measure the micro-rheology of the vitreous humor. The Brownian motion of the bead was observed using a fast camera and the micro-rheology determined by analysis of t... Read More about Investigating the microrheology of the vitreous humor using an optically trapped local probe.