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Paediatric clinical pharmacology in the UK

Choonara, Imti; Sammons, Helen

Authors

Imti Choonara

Helen Sammons



Abstract

Paediatric clinical pharmacology is the scientific study of medicines in children and is a relatively new subspecialty in paediatrics in the UK. Training encompasses both the study of the effectiveness of drugs in children (clinical trials) and aspects of drug toxicity (pharmacovigilance). Ethical issues in relation to clinical trials and also studies of the pharmacokinetics and drug metabolism in children are crucial. Paediatric patients require formulations that young children in particular are able to take. The scientific evidence generated from clinical trials, pharmacokinetic studies and studies of drug toxicity all need to be applied in order to ensure that medicines are used rationally in children.

Citation

Choonara, I., & Sammons, H. (2014). Paediatric clinical pharmacology in the UK. Archives of Disease in Childhood, 99(12), https://doi.org/10.1136/archdischild-2014-306853

Journal Article Type Article
Acceptance Date Aug 19, 2014
Online Publication Date Sep 8, 2014
Publication Date Dec 1, 2014
Deposit Date Sep 27, 2016
Publicly Available Date Mar 29, 2024
Journal Archives of Disease in Childhood
Print ISSN 0003-9888
Electronic ISSN 1468-2044
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 99
Issue 12
DOI https://doi.org/10.1136/archdischild-2014-306853
Public URL https://nottingham-repository.worktribe.com/output/993521
Publisher URL http://adc.bmj.com/content/99/12/1143

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