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Development of microspheres for biomedical applications: a review

Hossain, Kazi M. Zakir; Patel, Uresha; Ahmed, Ifty

Authors

Kazi M. Zakir Hossain

Uresha Patel



Abstract

An overview of microspheres manufactured for use in biomedical applications based on recent literature is presented in this review. Different types of glasses (i.e. silicate, borate, and phosphates), ceramics and polymer-based microspheres (both natural and synthetic) in the form of porous , non-porous and hollow structures that are either already in use or are currently being investigated within the biomedical area are discussed. The advantages of using microspheres in applications such as drug delivery, bone tissue engineering and regeneration, absorption and desorption of substances, kinetic release of the loaded drug components are also presented. This review also reports on the preparation and characterisation methodologies used for the manufacture of these microspheres. Finally, a brief summary of the existing challenges associated with processing these microspheres which requires further research and development are presented.

Citation

Hossain, K. M. Z., Patel, U., & Ahmed, I. (2015). Development of microspheres for biomedical applications: a review. Progress in Biomaterials, 4(1), https://doi.org/10.1007/s40204-014-0033-8

Journal Article Type Article
Acceptance Date Nov 25, 2014
Online Publication Date Dec 10, 2014
Publication Date Mar 1, 2015
Deposit Date Aug 23, 2017
Publicly Available Date Mar 29, 2024
Journal Progress in Biomaterials
Electronic ISSN 2194-0517
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 4
Issue 1
DOI https://doi.org/10.1007/s40204-014-0033-8
Keywords Microspheres; Porous; Glasses; Ceramics; Polymers; Tissue engineering and regenerative medicine
Public URL https://nottingham-repository.worktribe.com/output/984641
Publisher URL https://link.springer.com/article/10.1007%2Fs40204-014-0033-8

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