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The growing story of (ARABIDOPSIS) CRINKLY 4

Czyzewicz, Nathan; Nikonorova, Natalia; Meyer, Matthew R.; Sandal, Priyanka; Shah, Shweta; Vu, Lam Dai; Gevaert, Kris; Rao, A. Gururaj; De Smet, Ive

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Nathan Czyzewicz

Natalia Nikonorova

Matthew R. Meyer

Priyanka Sandal

Shweta Shah

Lam Dai Vu

Kris Gevaert

A. Gururaj Rao

Ive De Smet


Receptor kinases play important roles in plant growth and development, but only few of them have been functionally characterized in depth. Over the past decade CRINKLY 4 (CR4)-related research has peaked as a result of a newly discovered role of ARABIDOPSIS CR4 (ACR4) in the root. Here, we comprehensively review the available (A)CR4 literature and describe its role in embryo, seed, shoot, and root development, but we also flag an unexpected role in plant defence. In addition, we discuss ACR4 domains and protein structure, describe known ACR4-interacting proteins and substrates, and elaborate on the transcriptional regulation of ACR4. Finally, we address the missing knowledge in our understanding of ACR4 signalling.

Journal Article Type Article
Acceptance Date Apr 21, 2016
Online Publication Date May 21, 2016
Publication Date Aug 1, 2016
Deposit Date Oct 20, 2016
Publicly Available Date Oct 20, 2016
Journal Journal of Experimental Botany
Print ISSN 0022-0957
Electronic ISSN 1460-2431
Publisher Oxford University Press
Peer Reviewed Peer Reviewed
Volume 67
Issue 16
Keywords ACR4, Arabidopsis, embryo, epidermis, flower, maize, receptor kinase, root, rice, seed
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