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Alcohol Misuse and Injury Outcomes in Young People Aged 10–24

Lester, Louise; Baker, Ruth; Coupland, Carol; Orton, Elizabeth


Louise Lester

Ruth Baker

Professor of Medical Statistics


Purpose: The burden of alcohol-attributable disease is a global problem. Young people often present to emergency health-care services with alcohol intoxication but little is known about how best to intervene at that point to improve future health outcomes. This study aimed to assess whether young people with an alcohol-specific hospital admission are at increased risk of injury following discharge.
Methods: A cohort study was conducted using a general population of 10- to 24-year-olds identified using primary care medical records with linked hospital admission records between 1998 and 2013. Exposed individuals had an alcohol-specific admission. Unexposed individuals did not and were frequency matched by age (±5 years) and general practice (ratio 10:1). Incidence rates of injury-related hospital admission post discharge were calculated, and hazard ratios (HR) were estimated by Cox regression.
Results: The cohort comprised 11,042 exposed and 110,656 unexposed individuals with 4,944 injury-related admissions during follow-up (2,092 in exposed). Injury rates were six times higher in those with a prior alcohol admission (73.92 per 1,000 person-years, 95% confidence interval (CI) 70.82–77.16 vs. 12.36, 11.91–12.81). The risk of an injury admission was highest in the month following an alcohol-specific admission (adjusted HR = 15.62, 95% CI 14.08–17.34), and remained higher compared to those with no previous alcohol-specific admission at 1 year (HR 5.28 (95% CI 4.97–5.60)) and throughout follow-up.
Conclusions: Young people with an alcohol-specific admission are at increased risk of subsequent injury requiring hospitalization, especially immediately post discharge, indicating a need for prompt intervention as soon as alcohol misuse behaviors are identified.


Lester, L., Baker, R., Coupland, C., & Orton, E. (2018). Alcohol Misuse and Injury Outcomes in Young People Aged 10–24. Journal of Adolescent Health, 62(4), 450-456.

Journal Article Type Article
Acceptance Date Oct 9, 2017
Online Publication Date Dec 6, 2017
Publication Date 2018-04
Deposit Date Oct 26, 2017
Publicly Available Date Dec 6, 2017
Journal Journal of Adolescent Health
Print ISSN 1054-139X
Electronic ISSN 1879-1972
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 62
Issue 4
Pages 450-456
Keywords Alcohols, Hospitalization, Adolescent, Risk, Wounds and Injuries
Public URL
Publisher URL
Copyright Statement Copyright information regarding this work can be found at the following address:


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