Risk of skin cancer in people with vitiligo: a systematic review and meta-analysis

Ban, Lu; Labbouz, S.; Grindlay, Douglas J.C.; Batchelor, Jonathan M.; Ratib, Sonia

Abstract

Vitiligo is a chronic disorder causing skin depigmentation with around 1% global prevalence, affecting people of all ages, skin types and genders.1 Due to the absence of melanin in lesional skin there is a theoretical concern that there might be a higher risk of skin cancer in people with vitiligo. However, some studies have shown that the genetic and autoimmune profiles of vitiligo patients may confer a degree of protection against the development of melanoma and non‐melanoma skin cancer (NMSC).2 Therefore, the aim of this systematic review was to quantify the risk of skin cancer (melanoma and NMSC) in people with vitiligo compared to those without vitiligo.

Citation

Ban, L., Labbouz, S., Grindlay, D. J., Batchelor, J. M., & Ratib, S. (2018). Risk of skin cancer in people with vitiligo: a systematic review and meta-analysis. British Journal of Dermatology, 179(4), 971-972. https://doi.org/10.1111/bjd.16703

• Journal Article Type: Article
• Acceptance Date: Apr 5, 2018
• Online Publication Date: Apr 28, 2018
• Publication Date: Oct 31, 2018
• Deposit Date: Apr 10, 2018
• Publicly Available Date: Apr 29, 2019
• Journal: British Journal of Dermatology
• Print ISSN: 0007-0963
• Electronic ISSN: 1365-2133
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 179
• Issue: 4
• Pages: 971-972
• DOI: https://doi.org/10.1111/bjd.16703
• Public URL: https://nottingham-repository.worktribe.com/output/928998
• Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.16703
• Additional Information: This is the peer reviewed version of the following article, which has been published in final form at https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.16703. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.