Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method

Lim, Chang Nong; Koh, Kai Seng; Ren, Yong; Chin, Jit Kai; Shi, Yong; Yan, Yuying

Abstract

This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation. In this paper, two different designs are demonstrated, i.e., droplet fission (single layer) and droplet encapsulation (double layer). In addition, the current fabrication approach reduces the overall production interval with the introduction of a custom-made polydimethylsiloxane (PDMS) aligner. Apart from that, the fabricated device is able to generate daughter droplets with the coefficient of variance (CV) below 5% and double emulsions with CV maintained within 10% without involvement of complex surface wettability modification.

Citation

Lim, C. N., Koh, K. S., Ren, Y., Chin, J. K., Shi, Y., & Yan, Y. (2017). Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method. Micromachines, 8(2), Article 49. https://doi.org/10.3390/mi8020049

• Journal Article Type: Article
• Acceptance Date: Feb 4, 2017
• Publication Date: Feb 10, 2017
• Deposit Date: Oct 11, 2017
• Publicly Available Date: Oct 11, 2017
• Journal: Micromachines
• Electronic ISSN: 2072-666X
• Publisher: MDPI
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 2
• Article Number: 49
• DOI: https://doi.org/10.3390/mi8020049
• Keywords: droplet manipulation, microfabrication, encapsulation, fission
• Public URL: https://nottingham-repository.worktribe.com/output/846486
• Publisher URL: http://www.mdpi.com/2072-666X/8/2/49
• Contract Date: Oct 11, 2017