Modelling primary blast lung injury: current capability and future direction

Scott, Timothy; Hulse, E.; Haque, Mainul; Kirkman, E.; Hardman, J.G.; Mahoney, P.

Abstract

Primary blast lung injury frequently complicates military conflict and terrorist attacks on civilian populations. The fact that it occurs in areas of conflict or unpredictable mass casualty events makes clinical study in human casualties implausible. Research in this field is therefore reliant on the use of some form of biological or non-biological surrogate model. This article briefly reviews the modelling work undertaken in this field until now and describes the rationale behind the generation of an in silico physiological model.

Citation

Scott, T., Hulse, E., Haque, M., Kirkman, E., Hardman, J., & Mahoney, P. (in press). Modelling primary blast lung injury: current capability and future direction. Journal of the Royal Army Medical Corps, https://doi.org/10.1136/jramc-2016-000678

• Journal Article Type: Article
• Acceptance Date: Oct 11, 2016
• Online Publication Date: Nov 23, 2016
• Deposit Date: Nov 30, 2016
• Publicly Available Date: Nov 30, 2016
• Journal: Journal of the Royal Army Medical Corps
• Electronic ISSN: 2052-0468
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1136/jramc-2016-000678
• Public URL: https://nottingham-repository.worktribe.com/output/827351
• Publisher URL: http://jramc.bmj.com/content/early/2016/11/23/jramc-2016-000678
• Contract Date: Nov 30, 2016