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Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes

Rawson, Frankie J.; Cole, M.T; Aylott, Jonathan W.; Milne, W.I.; Collins, C.M.; Jackson, Simon K.; Silman, Nigel; Mendes, Paula M.; Hicks, Jacqueline

Authors

M.T Cole

W.I. Milne

C.M. Collins

Simon K. Jackson

Nigel Silman

Paula M. Mendes



Abstract

With the rapidly increasing demands for ultrasensitive biodetection, the design and applications of new nano-scale materials for development of sensors based on optical and electrochemical transducers have attracted substantial interest. In particular, given the comparable sizes of nanomaterials and biomolecules, there exist plenty of opportunities to develop functional nanoprobes with biomolecules for highly sensitive and selective biosensing, shedding new light on cellular behaviour. Towards this aim, herein we interface cells with patterned nano-arrays of carbon nanofibers forming a nanosensor-cell construct. We show that such a construct is capable of electrochemically communicating with the intracellular environment.

Journal Article Type Article
Journal Scientific Reports
Print ISSN 2045-2322
Electronic ISSN 2045-2322
Publisher Nature Publishing Group
Peer Reviewed Peer Reviewed
Volume 6
Issue 37672
APA6 Citation Rawson, F. J., Cole, M., Aylott, J. W., Milne, W., Collins, C., Jackson, S. K., …Hicks, J. (in press). Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes. Scientific Reports, 6(37672), https://doi.org/10.1038/srep37672
DOI https://doi.org/10.1038/srep37672
Publisher URL http://www.nature.com/articles/srep37672
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0





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