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Step 4: stick or twist? A review of asthma therapy

Slater, Mariel G.; Pavord, Ian D.; Shaw, Dominick E.

Authors

Mariel G. Slater

Ian D. Pavord



Abstract

Many people with asthma do not achieve disease control, despite bronchodilators and inhaled corticosteroid therapy. People with uncontrolled asthma are at higher risk of an asthma attack and death, with mortality rates estimated at 1000 deaths/ year in England and Wales. The recent National Review of Asthma Deaths (NRAD) report, ‘Why asthma still kills’, recommended that patients at step 4 or 5 of the British Thoracic Society/Scottish Intercollegiate Guidelines Network (BTS/SIGN) guidance must be referred to a specialist asthma service. This article reviews the 2014 evidence base for therapy of asthma patients at BTS/SIGN step 4 of the treatment cascade, in response to key findings of the NRAD report and lack of preferred treatment option at this step.

Citation

Slater, M. G., Pavord, I. D., & Shaw, D. E. (2016). Step 4: stick or twist? A review of asthma therapy. BMJ Open Respiratory Research, 3(1), 1-7. https://doi.org/10.1136/bmjresp-2016-000143

Journal Article Type Article
Acceptance Date Jul 6, 2016
Online Publication Date Sep 6, 2016
Publication Date Sep 6, 2016
Deposit Date Oct 24, 2016
Publicly Available Date Oct 24, 2016
Journal BMJ Open Respiratory Research
Electronic ISSN 2052-4439
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 3
Issue 1
Article Number e000143
Pages 1-7
DOI https://doi.org/10.1136/bmjresp-2016-000143
Public URL http://eprints.nottingham.ac.uk/id/eprint/37856
Publisher URL http://bmjopenrespres.bmj.com/content/3/1/e000143
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc/4.0

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BMJ Open Resp Res-2016-Slater-.pdf (1.1 Mb)
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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by-nc/4.0





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