Pre-surgery depression and confidence to manage problems predict recovery trajectories of health and wellbeing in the first two years following colorectal cancer: results from the CREW cohort study

Foster, Claire; Haviland, Joanne; Winter, Jane; Grimmett, Chloe; Chivers Seymour, Kim; Batehup, Lynn; Calman, Lynn; Corner, Jessica; Din, Amy; Fenlon, Deborah; May, Christine M.; Richardson, Alison; Smith, Peter W.; Souglakos, John

Abstract

Purpose
This paper identifies predictors of recovery trajectories of quality of life (QoL), health status and personal wellbeing in the two years following colorectal cancer surgery.

Methods
872 adults receiving curative intent surgery during November 2010 to March 2012. Questionnaires at baseline, 3, 9, 15, 24 months post-surgery assessed QoL, health status, wellbeing, confidence to manage illness-related problems (self-efficacy), social support, comorbidities, socio-demographic, clinical and treatment characteristics. Group-based trajectory analyses identified distinct trajectories and predictors for QoL, health status and wellbeing.

Results
Four recovery trajectories were identified for each outcome. Groups 1 and 2 fared consistently well (scores above/within normal range); 70.5%of participants for QoL, 33.3% health status, 77.6%wellbeing. Group 3 had some problems (24.2% QoL, 59.3% health, 18.2% wellbeing); Group 4 fared consistently poorly (5.3% QoL, 7.4% health, 4.2% wellbeing). Higher pre-surgery depression and lower self-efficacy were significantly associated with poorer trajectories for all three outcomes after adjusting for other important predictors including disease characteristics, stoma, anxiety and social support.

Conclusions
Psychosocial factors including self-efficacy and depression before surgery predict recovery trajectories in QoL, health status and wellbeing following colorectal cancer treatment independent of treatment or disease characteristics. This has significant implications for colorectal cancer management as appropriate support may be improved by early intervention resulting in more positive recovery experiences.

Citation

Foster, C., Haviland, J., Winter, J., Grimmett, C., Chivers Seymour, K., Batehup, L., …Souglakos, J. (2016). Pre-surgery depression and confidence to manage problems predict recovery trajectories of health and wellbeing in the first two years following colorectal cancer: results from the CREW cohort study. PLoS ONE, 11(5), e0155434. https://doi.org/10.1371/journal.pone.0155434

• Journal Article Type: Article
• Acceptance Date: Apr 28, 2016
• Online Publication Date: May 12, 2016
• Publication Date: May 12, 2016
• Deposit Date: Jun 14, 2016
• Publicly Available Date: Jun 14, 2016
• Journal: PLOS ONE
• Electronic ISSN: 1932-6203
• Publisher: Public Library of Science
• Peer Reviewed: Peer Reviewed
• Volume: 11
• Issue: 5
• Article Number: e0155434
• Pages: e0155434
• DOI: https://doi.org/10.1371/journal.pone.0155434
• Public URL: https://nottingham-repository.worktribe.com/output/790206
• Publisher URL: http://dx.doi.org/10.1371/journal.pone.0155434