Lee Jollans
Ventral striatum connectivity during reward anticipation in adolescent smokers
Jollans, Lee; Zhipeng, Cao; Icke, Ilknur; Greene, Ciara; Kelly, Clare; Banaschewski, Tobias; Bokde, Arun L. W.; Bromberg, Uli; B�chel, Christian; Cattrell, Anna; Conrod, Patricia J.; Desrivi�res, Sylvane; Flor, Herta; Frouin, Vincent; Gallinat, J�rgen; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Martinot, Jean-Luc; Artiges, Eric; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Paus, Tom�; Smolka, Michael N.; Walter, Henrik; Schumann, Gunter; Whelan, Robert
Authors
Cao Zhipeng
Ilknur Icke
Ciara Greene
Clare Kelly
Tobias Banaschewski
Arun L. W. Bokde
Uli Bromberg
Christian B�chel
Anna Cattrell
Patricia J. Conrod
Sylvane Desrivi�res
Herta Flor
Vincent Frouin
J�rgen Gallinat
Hugh Garavan
Professor PENNY GOWLAND PENNY.GOWLAND@NOTTINGHAM.AC.UK
Professor of Physics
Andreas Heinz
Bernd Ittermann
Jean-Luc Martinot
Eric Artiges
Frauke Nees
Dimitri Papadopoulos Orfanos
Tom� Paus
Michael N. Smolka
Henrik Walter
Gunter Schumann
Robert Whelan
Abstract
Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction.
Citation
Jollans, L., Zhipeng, C., Icke, I., Greene, C., Kelly, C., Banaschewski, T., …Whelan, R. (in press). Ventral striatum connectivity during reward anticipation in adolescent smokers. Developmental Neuropsychology, 41(1-2), https://doi.org/10.1080/87565641.2016.1164172
Journal Article Type | Article |
---|---|
Acceptance Date | Mar 15, 2016 |
Online Publication Date | Apr 13, 2016 |
Deposit Date | May 9, 2017 |
Publicly Available Date | May 9, 2017 |
Journal | Developmental Neuropsychology |
Print ISSN | 8756-5641 |
Electronic ISSN | 1532-6942 |
Publisher | Routledge |
Peer Reviewed | Peer Reviewed |
Volume | 41 |
Issue | 1-2 |
DOI | https://doi.org/10.1080/87565641.2016.1164172 |
Public URL | https://nottingham-repository.worktribe.com/output/785375 |
Publisher URL | http://www.tandfonline.com/doi/full/10.1080/87565641.2016.1164172 |
Additional Information | Date of acceptance is estimated. // This is an Accepted Manuscript of an article published by Taylor & Francis in Developmental Neuropsychology on 13 April 2016, available online: http://www.tandfonline.com/10.1080/87565641.2016.1164172. |
Contract Date | May 9, 2017 |
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