Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

Smith, Joshua J.; Best, Daniel; Lam, Hon Wai

Abstract

Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.

Citation

Smith, J. J., Best, D., & Lam, H. W. (2016). Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines. Chemical Communications, https://doi.org/10.1039/C6CC00603E

• Journal Article Type: Article
• Publication Date: Feb 17, 2016
• Deposit Date: Feb 18, 2016
• Publicly Available Date: Feb 18, 2016
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Electronic ISSN: 1364-548X
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1039/C6CC00603E
• Public URL: https://nottingham-repository.worktribe.com/output/776127
• Publisher URL: http://pubs.rsc.org/en/Content/ArticleLanding/2016/CC/C6CC00603E#!divAbstract