Strategies for using topical corticosteroids in children and adults with eczema

Lax, Stephanie; Harvey, Jane; Axon, Emma; Howells, Laura; Santer, Miriam; Ridd, Matthew; Lawton, Sandra; Langan, Sinéad; Roberts, Amanda; Ahmed, Amina; Muller, Ingrid; Ming, Long Chiau; Panda, Saumya; Chernyshov, Pavel; Carter, Ben; Williams, Hywel; Thomas, Kim; Chalmers, Joanne

Abstract

Background Eczema is a common skin condition. Although topical corticosteroids (TCS) have been a first-line treatment for eczema for decades, there are uncertainties over their optimal use. Objectives To establish the effectiveness and safety of different ways of using TCS for treating eczema. Search methods We searched databases to January 2021 (Cochrane Skin Specialised Register; CENTRAL; MEDLINE; Embase; GREAT). Five clinical trial registers were also searched. Bibliographies from included studies were checked to identify further trials. Selection criteria Randomised controlled trials in adults and children with eczema comparing at least two strategies of TCS use. Placebo comparisons were excluded, other than for studies evaluating proactive versus reactive treatment.

Citation

Lax, S., Harvey, J., Axon, E., Howells, L., Santer, M., Ridd, M., …Chalmers, J. (2022). Strategies for using topical corticosteroids in children and adults with eczema. Cochrane Database of Systematic Reviews, 3(3), Article CD013356

• Journal Article Type: Article
• Acceptance Date: Jan 5, 2022
• Online Publication Date: Mar 11, 2022
• Publication Date: Mar 11, 2022
• Deposit Date: Feb 11, 2022
• Publicly Available Date: Mar 12, 2022
• Journal: Cochrane Database of Systematic Reviews
• Electronic ISSN: 1469-493X
• Publisher: Cochrane Collaboration
• Peer Reviewed: Peer Reviewed
• Volume: 3
• Issue: 3
• Article Number: CD013356
• Public URL: https://nottingham-repository.worktribe.com/output/7416744
• Publisher URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916090/