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Comparison of the benefits of cochlear implantation versus contra-lateral routing of signal hearing aids in adult patients with single-sided deafness: study protocol for a prospective within-subject longitudinal trial

Kitterick, Pádraig T.; O’Donoghue, Gerard M.; Edmondson-Jones, Mark; Marshall, Andrew; Jeffs, Ellen; Craddock, Louise; Riley, Alison; Green, Kevin; O'Driscoll, Martin; Jiang, Dan; Nunn, Terry; Saeed, Shakeel; Aleksy, Wanda; Seeber, Bernhard U.

Authors

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DR PADRAIG KITTERICK Padraig.Kitterick@nottingham.ac.uk
Associate Professor in Hearing Sciences Translational Hearing Research

Gerard M. O’Donoghue

Mark Edmondson-Jones mark.edmondson-jones@nottingham.ac.uk

Andrew Marshall

Ellen Jeffs

Louise Craddock

Alison Riley

Kevin Green

Martin O'Driscoll

Dan Jiang

Terry Nunn

Shakeel Saeed

Wanda Aleksy

Bernhard U. Seeber



Abstract

Background


Individuals with a unilateral severe-to-profound hearing loss, or single-sided deafness, report difficulty with listening in many everyday situations despite having access to well-preserved acoustic hearing in one ear. The standard of care for single-sided deafness available on the UK National Health Service is a contra-lateral routing of signals hearing aid which transfers sounds from the impaired ear to the non-impaired ear. This hearing aid has been found to improve speech understanding in noise when the signal-to-noise ratio is more favourable at the impaired ear than the non-impaired ear. However, the indiscriminate routing of signals to a single ear can have detrimental effects when interfering sounds are located on the side of the impaired ear. Recent published evidence has suggested that cochlear implantation in individuals with a single-sided deafness can restore access to the binaural cues which underpin the ability to localise sounds and segregate speech from other interfering sounds.

Methods/Design


The current trial was designed to assess the efficacy of cochlear implantation compared to a contra-lateral routing of signals hearing aid in restoring binaural hearing in adults with acquired single-sided deafness. Patients are assessed at baseline and after receiving a contra-lateral routing of signals hearing aid. A cochlear implant is then provided to those patients who do not receive sufficient benefit from the hearing aid. This within-subject longitudinal design reflects the expected care pathway should cochlear implantation be provided for single-sided deafness on the UK National Health Service. The primary endpoints are measures of binaural hearing at baseline, after provision of a contra-lateral routing of signals hearing aid, and after cochlear implantation. Binaural hearing is assessed in terms of the accuracy with which sounds are localised and speech is perceived in background noise. The trial is also designed to measure the impact of the interventions on hearing- and health-related quality of life.

Discussion


This multi-centre trial was designed to provide evidence for the efficacy of cochlear implantation compared to the contra-lateral routing of signals. A purpose-built sound presentation system and established measurement techniques will provide reliable and precise measures of binaural hearing.

Trial registration


Current Controlled Trials http://www.controlled-trials.com/ISRCTN33301739 (05/JUL/2013)

Citation

Kitterick, P. T., O’Donoghue, G. M., Edmondson-Jones, M., Marshall, A., Jeffs, E., Craddock, L., …Seeber, B. U. (2014). Comparison of the benefits of cochlear implantation versus contra-lateral routing of signal hearing aids in adult patients with single-sided deafness: study protocol for a prospective within-subject longitudinal trial. BMC Ear, Nose and Throat Disorders, 14, https://doi.org/10.1186/1472-6815-14-7

Journal Article Type Article
Acceptance Date Jul 18, 2014
Publication Date Aug 11, 2014
Deposit Date Dec 9, 2016
Publicly Available Date Dec 9, 2016
Journal BMC Ear, Nose and Throat Disorders
Electronic ISSN 1472-6815
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 14
Article Number 7
DOI https://doi.org/10.1186/1472-6815-14-7
Keywords Cochlear implantation, Single-sided deafness, Unilateral hearing loss, Contra-lateral routing of signals, Hearing aid, Binaural hearing, Spatial listening
Public URL http://eprints.nottingham.ac.uk/id/eprint/39261
Publisher URL http://dx.doi.org/10.1186/1472-6815-14-7
Related Public URLs http://bmcearnosethroatdisord.biomedcentral.com/articles/10.1186/1472-6815-14-7
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf

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Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/

Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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