Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study
Hurley, Matthew; McKeever, Tricia M.; Prayle, Andrew P.; Smyth, Alan R.; Fogarty, Andrew W.
TRICIA MCKEEVER firstname.lastname@example.org
Professor of Epidemiology and Medical Statistics
ANDREW PRAYLE email@example.com
Clinical Associate Professor
ALAN SMYTH firstname.lastname@example.org
Professor of Child Health
ANDREW FOGARTY email@example.com
Clinical Associate Professor & Reader in Clinical Epidemiology
Background: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement.
Method: Death registration data analysis (US, England & Wales (E&W)—1972–2009).
Results: CF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed.
Conclusion: The median age of death of people with CF is improving more rapidly than that of the general population in US and E&W.
Hurley, M., McKeever, T. M., Prayle, A. P., Smyth, A. R., & Fogarty, A. W. (2014). Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study. Journal of Cystic Fibrosis, 13(4), doi:10.1016/j.jcf.2013.12.002
|Journal Article Type||Article|
|Acceptance Date||Sep 20, 2013|
|Online Publication Date||Jan 10, 2014|
|Publication Date||Jul 1, 2014|
|Deposit Date||Feb 15, 2016|
|Publicly Available Date||Feb 15, 2016|
|Journal||Journal of Cystic Fibrosis|
|Peer Reviewed||Peer Reviewed|
|Keywords||Cystic fibrosis; Survival; Mortality; Healthcare|
|Copyright Statement||Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0|
Hurley JCF 2014 Rate of improvement in life expectancy.pdf
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0
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