Skip to main content

Research Repository

Advanced Search

The psychological impact of the unpredictability of multiple sclerosis: a qualitative literature meta-synthesis

Rose, Hannah; das Nair, Roshan


Hannah Rose

Professor of Clinical Psychology and Neuropsychology


Background: Multiple sclerosis (MS) is a neurological conditioncharacterised by an unpredictable nature. This characteristic is reported to be the largest challenge for individuals with the condition. Chronic illness literature highlights the psychological impact of unpredictability, but there is a paucity of research examining this concept in MS.

Objectives: This systematic review aimed to explore the psychological impact of unpredictability in MS.

Methods: A meta-synthesis was conducted. A total of 6 studies with 59 participants were reviewed and critically appraised. Themes relating to the psychological impact of unpredictability were extracted and synthesised.

Results: A preliminary model of the unpredictability of MS was developed highlighting the different psychological impacts of diagnosis, remission and relapse.

Conclusions: The psychological impact of unpredictability alters through diagnosis, remission and relapse. Further research is required to explore the experience of unpredictability in MS.


Rose, H., & das Nair, R. (in press). The psychological impact of the unpredictability of multiple sclerosis: a qualitative literature meta-synthesis. British Journal of Neuroscience Nursing, 9(4),

Journal Article Type Article
Acceptance Date Jun 19, 2013
Online Publication Date Sep 27, 2013
Deposit Date Jul 18, 2016
Publicly Available Date Jul 18, 2016
Journal British Journal of Neuroscience Nursing
Print ISSN 1747-0307
Electronic ISSN 1747-0307
Publisher Mark Allen Healthcare
Peer Reviewed Peer Reviewed
Volume 9
Issue 4
Keywords Multiple sclerosis, psychological impact, unpredictability, systematic review, qualitative, synthesis
Public URL
Publisher URL


You might also like

Downloadable Citations