Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver

Shore, Andrew M.; Karamitri, Angeliki; Kemp, Paul; Speakman, John R.; Graham, Neil S.; Lomax, Michael A.

Abstract

Cold exposure imposes a metabolic challenge to mammals that is met by a coordinated response in different tissues to prevent hypothermia. This study reports a transcriptomic analysis in brown adipose tissue (BAT), white adipose (WAT) and liver of mice in response to 24 h cold exposure at 8°C. Expression of 1895 genes were significantly (P

Citation

Shore, A. M., Karamitri, A., Kemp, P., Speakman, J. R., Graham, N. S., & Lomax, M. A. (2013). Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver. PLoS ONE, 8(7), doi:10.1371/journal.pone.0068933

• Journal Article Type: Article
• Publication Date: Jul 22, 2013
• Deposit Date: Apr 1, 2014
• Publicly Available Date: Apr 1, 2014
• Journal: PLoS ONE
• Electronic ISSN: 1932-6203
• Publisher: Public Library of Science
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 7
• Article Number: e68933
• DOI: https://doi.org/10.1371/journal.pone.0068933
• Public URL: http://eprints.nottingham.ac.uk/id/eprint/2532
• Publisher URL: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068933
• Copyright Statement: Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0