Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver

Shore, Andrew M.; Karamitri, Angeliki; Kemp, Paul; Speakman, John R.; Graham, Neil S.; Lomax, Michael A.

Abstract

Cold exposure imposes a metabolic challenge to mammals that is met by a coordinated response in different tissues to prevent hypothermia. This study reports a transcriptomic analysis in brown adipose tissue (BAT), white adipose (WAT) and liver of mice in response to 24 h cold exposure at 8°C. Expression of 1895 genes were significantly (P

• Journal Article Type: Article
• Publication Date: Jul 22, 2013
• Deposit Date: Apr 1, 2014
• Publicly Available Date: Apr 1, 2014
• Journal: PLoS ONE
• Electronic ISSN: 1932-6203
• Publisher: Public Library of Science
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 7
• Article Number: e68933
• DOI: https://doi.org/10.1371/journal.pone.0068933
• Public URL: https://nottingham-repository.worktribe.com/output/716342
• Publisher URL: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068933