Pulsed ultrasound modulated optical tomography utilizing the harmonic response of lock-in detection

Ruan, H.; Mather, M.L.; Morgan, Stephen P.

Abstract

Ultrasound modulated optical tomography (USMOT) can image the optical properties of a scattering
medium at a spatial resolution approaching that of ultrasound (US). A lock-in parallel speckle detection
technique is proposed to detect pulsed US modulated light using a multipixel detector. The frequency
components of the pass band match those of the US pulse train and provide efficient detection. The modulation
depth is extracted by taking the difference between a pair of speckle patterns modulated by a pair
of phase-inversed US bursts. Modification to pulse inversion mode enables the second harmonic US
modulation due to nonlinear US propagation to be detected. © 2013 Optical Society of America
OCIS codes: (110.6150) Speckle imaging; (110.0113) Imaging through turbid media.

• Journal Article Type: Article
• Publication Date: Jul 1, 2013
• Journal: Applied Optics
• Print ISSN: 1559-128X
• Electronic ISSN: 1559-128X
• Publisher: Optical Society of America
• Peer Reviewed: Peer Reviewed
• Volume: 52
• Issue: 19
• APA6 Citation: Ruan, H., Mather, M., & Morgan, S. P. (2013). Pulsed ultrasound modulated optical tomography utilizing the harmonic response of lock-in detection. Applied Optics, 52(19), doi:10.1364/AO.52.004755
• DOI: https://doi.org/10.1364/AO.52.004755
• Publisher URL: http://www.opticsinfobase.org/ao/abstract.cfm?uri=ao-52-19-4755
• Copyright Statement: Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf