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Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays

Hook, Andrew L.; Chang, Chien-Yi; Yang, Jing; Atkinson, Steve; Langer, Robert; Anderson, Daniel G.; Davies, Martyn C.; Williams, Paul; Alexander, Morgan R.

Authors

ANDREW HOOK ANDREW.HOOK@NOTTINGHAM.AC.UK
Nottingham Research Fellow

Chien-Yi Chang

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JING YANG JING.YANG@NOTTINGHAM.AC.UK
Assistant Professor

Robert Langer

Daniel G. Anderson

Martyn C. Davies

PAUL WILLIAMS paul.williams@nottingham.ac.uk
Professor of Molecular Microbiology



Abstract

A new class of bacteria-attachment-resistant materials is discovered using a multi-generation polymer microarray methodology that reduces bacterial attachment by up to 99.3% compared with a leading commercially available silver hydrogel anti-bacterial material. The coverage of three bacterial species, Pseudomonas aeruginosa, Staphylococcus aureus, and uropathogenic Escherichia coli is assessed.

Citation

Hook, A. L., Chang, C., Yang, J., Atkinson, S., Langer, R., Anderson, D. G., …Alexander, M. R. (2013). Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays. Advanced Materials, 25(18), doi:10.1002/adma.201204936

Journal Article Type Article
Publication Date May 14, 2013
Deposit Date Apr 15, 2014
Publicly Available Date Apr 15, 2014
Journal Advanced Materials
Print ISSN 0935-9648
Electronic ISSN 0935-9648
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 25
Issue 18
DOI https://doi.org/10.1002/adma.201204936
Public URL http://eprints.nottingham.ac.uk/id/eprint/2953
Publisher URL http://onlinelibrary.wiley.com/doi/10.1002/adma.201204936/full
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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