Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays

Hook, Andrew L.; Chang, Chien-Yi; Yang, Jing; Atkinson, Steve; Langer, Robert; Anderson, Daniel G.; Davies, Martyn C.; Williams, Paul; Alexander, Morgan R.

Abstract

A new class of bacteria-attachment-resistant materials is discovered using a multi-generation polymer microarray methodology that reduces bacterial attachment by up to 99.3% compared with a leading commercially available silver hydrogel anti-bacterial material. The coverage of three bacterial species, Pseudomonas aeruginosa, Staphylococcus aureus, and uropathogenic Escherichia coli is assessed.

Citation

Hook, A. L., Chang, C.-Y., Yang, J., Atkinson, S., Langer, R., Anderson, D. G., …Alexander, M. R. (2013). Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays. Advanced Materials, 25(18), https://doi.org/10.1002/adma.201204936

• Journal Article Type: Article
• Publication Date: May 14, 2013
• Deposit Date: Apr 15, 2014
• Publicly Available Date: Apr 15, 2014
• Journal: Advanced Materials
• Print ISSN: 0935-9648
• Electronic ISSN: 1521-4095
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 25
• Issue: 18
• DOI: https://doi.org/10.1002/adma.201204936
• Public URL: https://nottingham-repository.worktribe.com/output/715184
• Publisher URL: http://onlinelibrary.wiley.com/doi/10.1002/adma.201204936/full