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New treatments for atopic dermatitis

Williams, Hywel

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Professor of Dermato-Epidemiology


Atopic dermatitis now affects 15% to 20% of chil­dren in developed countries, and prevalence in cities in developing countries undergoingrapid demographic changes is quickly following suit. [1] Most cases of atopic dermatitis in a given communityare mild, but children with moderate to severe diseasecan have continuous itching and associated loss of sleep. The social stigma of a visible skin disease can alsobe soul destroying for both patient and family. A few studies have suggested that some degree of preventionof the disease is possible, [2] although these measures have not been taken up widely. In the absence of any treatment that is known to alter the clinical course of the disease, most treatment is aimed at reducing symp­toms and signs. After a relative lull of almost 40 years, new drugs — tacrolimus and pimecrolimus — have appeared that offer different approaches to managing this miserable disease. Do they work? Are they safe? And how do they compare with existing treatments?


Williams, H. (2002). New treatments for atopic dermatitis. British medical journal, 324,

Journal Article Type Article
Publication Date Jun 29, 2002
Deposit Date Mar 20, 2008
Publicly Available Date Mar 20, 2008
Journal British Medical Journal
Print ISSN 0007-1447
Peer Reviewed Peer Reviewed
Volume 324
Public URL