Multicentre randomised controlled trial of a group psychological intervention for postnatal depression in British mothers of South Asian origin (ROSHNI-2): Study protocol

Husain, Nusrat; Lovell, Karina; Chew-Graham, Carolyn A.; Lunat, Farah; McPhillips, Rebecca; Atif, Najia; Aseem, Saadia; Begum, Jasmin; Bee, Penny; Bhui, Kamaldeep; Bower, Peter; Brugha, Traolach; Bhatti, Nafeesa; Chaudhry, Nasim; Davies, Linda; Gire, Nadeem; Islam, Anharul; Kai, Joe; Morrison, Jill; Mohmed, Naeem; Neelam, Jyothi; Rahman, Atif; Rathod, Shanaya; Siddiqi, Najma; Shah, Sadia; Shiri, Tinevimbo; Waheed, Waquas; Mirza, Ilyas; Williams, Chris; Zaidi, Nosheen; Emsley, Richard; Morriss, Richard

Abstract

Background In the UK, postnatal depression is more common in British South Asian women than White Caucasion women. Cognitive-behavioural therapy (CBT) is recommended as a first-line treatment, but there is little evidence for the adaptation of CBT for postnatal depression to ensure its applicability to different ethnic groups. Aims To evaluate the clinical and cost-effectiveness of a CBT-based positive health programme group intervention in British South Asian women with postnatal depression. Method We have designed a multicentre, two-arm, partially nested, randomised controlled trial with 4- and 12-month follow-up, comparing a 12-session group CBT-based intervention (positive health programme) plus treatment as usual with treatment as usual alone, for British South Asian women with postnatal depression. Participants will be recruited from primary care and appropriate community venues in areas of high South Asian density across the UK. It has been estimated that randomising 720 participants (360 into each group) will be sufficient to detect a clinically important difference between a 55% recovery rate in the intervention group and a 40% recovery rate in the treatment-as-usual group. An economic analysis will estimate the cost-effectiveness of the positive health programme. A qualitative process evaluation will explore barriers and enablers to study participation and examine the acceptability and impact of the programme from the perspective of British South Asian women and other key stakeholders.

• Journal Article Type: Article
• Acceptance Date: Aug 13, 2021
• Online Publication Date: Dec 1, 2021
• Publication Date: Jan 1, 2022
• Deposit Date: Dec 7, 2021
• Publicly Available Date: Dec 7, 2021
• Journal: BJPsych Open
• Electronic ISSN: 2056-4724
• Publisher: Royal College of Psychiatrists
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 1
• Article Number: E2
• DOI: https://doi.org/10.1192/bjo.2021.1032
• Keywords: Perinatal psychiatry; depressive disorders; cognitive–behavioural therapies; psychosocial interventions; randomised controlled trial.
• Public URL: https://nottingham-repository.worktribe.com/output/6909073
• Publisher URL: https://www.cambridge.org/core/journals/bjpsych-open/article/multicentre-randomised-controlled-trial-of-a-group-psychological-intervention-for-postnatal-depression-in-british-mothers-of-south-asian-origin-roshni2-study-protocol/400B91AB3F3D577F0314B9A1E62
• Additional Information: Copyright: Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists; License: This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.; Free to read: This content has been made available to all.