Bowel Preparation for Colorectal Surgery: Have All Questions Been Answered?

Ljungqvist, Olle; Lobo, Dileep N.

Abstract

Rosenberg and colleagues1 first proposed the use of nonabsorbable oral antibiotic preparation (OAB) for colorectal surgery in 1971. In a randomized clinical trial, they demonstrated a reduction in surgical site infection and anastomotic leak rates after combined mechanical bowel preparation (MBP) and 1 or 2 nonabsorbable oral antibiotics (phthalylsulphathiazole and phthalylsulphathiazole and neomycin, respectively) compared with MBP alone.

• Journal Article Type: Note
• Acceptance Date: Sep 8, 2021
• Online Publication Date: Oct 20, 2021
• Publication Date: Oct 20, 2021
• Deposit Date: Oct 27, 2021
• Journal: JAMA Surgery
• Print ISSN: 2168-6254
• Electronic ISSN: 2168-6262
• Publisher: American Medical Association (AMA)
• Peer Reviewed: Peer Reviewed
• Volume: 157
• Issue: 1
• Pages: 41-42
• DOI: https://doi.org/10.1001/jamasurg.2021.5273
• Keywords: Surgery
• Public URL: https://nottingham-repository.worktribe.com/output/6540007
• Publisher URL: https://jamanetwork.com/journals/jamasurgery/fullarticle/2785370