Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment

Corsetti, Maura; Brown, Steven; Chiarioni, Giuseppe; Dimidi, Eirini; Dudding, Thomas; Emmanuel, Anton; Fox, Mark; Ford, Alexander C.; Giordano, Pasquale; Grossi, Ugo; Henderson, Michelle; Knowles, Charles H.; O�Connell, P. Ronan; Quigley, Eamonn M.M.; Simren, Magnus; Spiller, Robin; Whelan, Kevin; Whitehead, William E.; Williams, Andrew B.; Scott, S. Mark

Abstract

Background: Chronic constipation is a prevalent disorder that affects quality of life of patients and consumes resources in healthcare systems worldwide. In clinical practice, it is still considered a challenge as clinicians frequently are unsure as to which treatments to use and when. Over a decade ago, a Neurogastroenterology and Motility journal supplement devoted to the investigation and management of constipation was published (Neurogastroenterol Motil 2009;21(Suppl.2)). In October 2018, the 3rd London Masterclass, entitled ‘Contemporary management of constipation’ was held. The faculty members of this symposium were invited to write two reviews to present a collective synthesis of talks presented and discussions held during this meeting. The first review addresses epidemiology, diagnosis, clinical associations, pathophysiology and investigation. Purpose: The present is the second of these reviews, providing contemporary perspectives and clinical challenges regarding behavioural, conservative, medical and surgical treatments for patients presenting with constipation. It includes a management algorithm to guide clinical practice.

Citation

Corsetti, M., Brown, S., Chiarioni, G., Dimidi, E., Dudding, T., Emmanuel, A., Fox, M., Ford, A. C., Giordano, P., Grossi, U., Henderson, M., Knowles, C. H., O’Connell, P. R., Quigley, E. M., Simren, M., Spiller, R., Whelan, K., Whitehead, W. E., Williams, A. B., & Scott, S. M. (2021). Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment. Neurogastroenterology and Motility, 33(7), Article e14070. https://doi.org/10.1111/nmo.14070

• Journal Article Type: Review
• Acceptance Date: Dec 14, 2020
• Online Publication Date: Feb 1, 2021
• Publication Date: 2021-07
• Deposit Date: Dec 14, 2020
• Publicly Available Date: Feb 2, 2022
• Journal: Neurogastroenterology and Motility
• Print ISSN: 1350-1925
• Electronic ISSN: 1365-2982
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 33
• Issue: 7
• Article Number: e14070
• DOI: https://doi.org/10.1111/nmo.14070
• Keywords: Gastroenterology; Physiology; Endocrine and Autonomic Systems
• Public URL: https://nottingham-repository.worktribe.com/output/5147820
• Publisher URL: https://onlinelibrary.wiley.com/doi/10.1111/nmo.14070