Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

John, Alison E.; Graves, Rebecca H.; Pun, K. Tao; Vitulli, Giovanni; Forty, Ellen J.; Mercer, Paul F.; Morrell, Josie L.; Barrett, John W.; Rogers, Rebecca F.; Hafeji, Maryam; Bibby, Lloyd I.; Gower, Elaine; Morrison, Valerie S.; Man, Yim; Roper, James A.; Luckett, Jeni C.; Borthwick, Lee A.; Barksby, Ben S.; Burgoyne, Rachel A.; Barnes, Rory; Le, Joelle; Flint, David J.; Pyne, Susan; Habgood, Anthony; Organ, Louise A.; Joseph, Chitra; Edwards-Pritchard, Rochelle C.; Maher, Toby M.; Fisher, Andrew J.; Gudmann, Natasja St�hr; Leeming, Diana J.; Chambers, Rachel C.; Lukey, Pauline T.; Marshall, Richard P.; Macdonald, Simon J. F.; Jenkins, R. Gisli; Slack, Robert J.

doi:10.1038/s41467-020-18397-6

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

John, Alison E.; Graves, Rebecca H.; Pun, K. Tao; Vitulli, Giovanni; Forty, Ellen J.; Mercer, Paul F.; Morrell, Josie L.; Barrett, John W.; Rogers, Rebecca F.; Hafeji, Maryam; Bibby, Lloyd I.; Gower, Elaine; Morrison, Valerie S.; Man, Yim; Roper, James A.; Luckett, Jeni C.; Borthwick, Lee A.; Barksby, Ben S.; Burgoyne, Rachel A.; Barnes, Rory; Le, Joelle; Flint, David J.; Pyne, Susan; Habgood, Anthony; Organ, Louise A.; Joseph, Chitra; Edwards-Pritchard, Rochelle C.; Maher, Toby M.; Fisher, Andrew J.; Gudmann, Natasja St�hr; Leeming, Diana J.; Chambers, Rachel C.; Lukey, Pauline T.; Marshall, Richard P.; Macdonald, Simon J. F.; Jenkins, R. Gisli; Slack, Robert J.

Authors

Alison E. John

Rebecca H. Graves

K. Tao Pun

Giovanni Vitulli

Ellen J. Forty

Paul F. Mercer

Josie L. Morrell

John W. Barrett

Rebecca F. Rogers

Maryam Hafeji

Lloyd I. Bibby

Elaine Gower

Valerie S. Morrison

Yim Man

James A. Roper

JENI LUCKETT JENI.LUCKETT@NOTTINGHAM.AC.UK
Senior Research Fellow

Lee A. Borthwick

Ben S. Barksby

Rachel A. Burgoyne

Rory Barnes

Joelle Le

David J. Flint

Susan Pyne

Anthony Habgood

Louise A. Organ

Dr CHITRA JOSEPH CHITRA.JOSEPH@NOTTINGHAM.AC.UK
Research Fellow

Rochelle C. Edwards-Pritchard

Toby M. Maher

Andrew J. Fisher

Natasja St�hr Gudmann

Diana J. Leeming

Rachel C. Chambers

Pauline T. Lukey

Richard P. Marshall

Simon J. F. Macdonald

R. Gisli Jenkins

Robert J. Slack

Citation

John, A. E., Graves, R. H., Pun, K. T., Vitulli, G., Forty, E. J., Mercer, P. F., …Slack, R. J. (2020). Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis. Nature Communications, 11(1), Article 4659. https://doi.org/10.1038/s41467-020-18397-6

Journal Article Type	Article
Acceptance Date	Aug 17, 2020
Online Publication Date	Sep 16, 2020
Publication Date	2020-12
Deposit Date	Dec 15, 2020
Publicly Available Date	Dec 15, 2020
Journal	Nature Communications
Electronic ISSN	2041-1723
Publisher	Nature Publishing Group
Peer Reviewed	Peer Reviewed
Volume	11
Issue	1
Article Number	4659
DOI	https://doi.org/10.1038/s41467-020-18397-6
Keywords	General Biochemistry, Genetics and Molecular Biology; General Physics and Astronomy; General Chemistry
Public URL	https://nottingham-repository.worktribe.com/output/4928534
Publisher URL	https://www.nature.com/articles/s41467-020-18397-6