T. H. Morris
Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds
Morris, T. H.; Paine, S. W.; Zahra, P. W.; Li, E. C.; Colgan, S .A.; Karamatic, S. L.
Authors
STUART PAINE Stuart.Paine@nottingham.ac.uk
Professor of Pharmacometrics
P. W. Zahra
E. C. Li
S .A. Colgan
S. L. Karamatic
Abstract
Animals used in sport should be treated as required to ensure animal welfare but any such use of medication should also be controlled to ensure integrity. Pharmacokinetic studies on groups of six greyhounds were performed to measure plasma and urine levels of carprofen and firocoxib to inform medication control advice. Using the standard methodology for medication control the Irrelevant Plasma Concentration was determined as 20 ng/mL and 2 ng/mL for carprofen and firocoxib respectively. The Irrelevant Urine Concentration was also determined as 0.3 ng/ml and 2 ng/mL for carprofen and firocoxib respectively. These Irrelevant Plasma and Urine Concentrations will allow
Citation
Morris, T. H., Paine, S. W., Zahra, P. W., Li, E. C., Colgan, S. .., & Karamatic, S. L. (2020). Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds. Australian Veterinary Journal, 98(12), 578-585. https://doi.org/10.1111/avj.13014
Journal Article Type | Article |
---|---|
Acceptance Date | Aug 6, 2020 |
Online Publication Date | Sep 2, 2020 |
Publication Date | 2020-12 |
Deposit Date | Aug 12, 2020 |
Publicly Available Date | Mar 29, 2024 |
Journal | Australian Veterinary Journal |
Print ISSN | 0005-0423 |
Electronic ISSN | 1751-0813 |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
Volume | 98 |
Issue | 12 |
Pages | 578-585 |
DOI | https://doi.org/10.1111/avj.13014 |
Keywords | carprofen, firocoxib, greyhound, pharmacokinetics, racing |
Public URL | https://nottingham-repository.worktribe.com/output/4828216 |
Publisher URL | https://onlinelibrary.wiley.com/doi/full/10.1111/avj.13014 |
Files
avj.13014 (1)
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PDF
Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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