Skip to main content

Research Repository

Advanced Search

Developing a fatigue programme: Protocol for the Nottingham Fatigue After Stroke (NotFAST2) study

Drummond, Avril; Ablewhite, Joanne; Condon, Laura; Nair, Roshan das; Jones, Amanda; Jones, Fiona; Sprigg, Nikola; Thomas, Shirley


Professor of Healthcare Research

Professor of Clinical Psychology and Neuropsychology

Amanda Jones

Fiona Jones

Professor of Stroke Medicine


Introduction: Post-stroke fatigue (PSF) is common and is one of the most distressing symptoms after stroke. It has a negative impact on physical, social and psychological functioning: it is also associated with poor outcomes and increased mortality. The effective management of PSF is therefore regarded as a clinical priority.

Method: Mixed-methods design with three overlapping phases. Phase 1 will be a survey of existing fatigue management within the UK. In phase 2, interviews and focus groups will be conducted with stroke survivors with fatigue, carers and clinicians to determine strategies used to manage fatigue successfully. In phase 3, data from phases 1 and 2 will contribute to the co-design of a fatigue management programme with the [NotFAST2] study Patient and Public Involvement group. This will be further refined through subsequent focus groups which will include those with fatigue associated with other health conditions.

Results: Survey data will be analysed using descriptive statistics. Interview and focus group data will be analysed using a framework approach.

Conclusion: PSF requires a comprehensive management programme necessitating input from key stakeholders. A PSF programme will be developed which will be tested in a future randomised controlled trial.


Drummond, A., Ablewhite, J., Condon, L., Nair, R. D., Jones, A., Jones, F., …Thomas, S. (2020). Developing a fatigue programme: Protocol for the Nottingham Fatigue After Stroke (NotFAST2) study. British Journal of Occupational Therapy, 83(11), 674-679.

Journal Article Type Article
Acceptance Date Jul 1, 2020
Online Publication Date Aug 20, 2020
Publication Date Nov 1, 2020
Deposit Date Jul 7, 2020
Publicly Available Date Aug 20, 2020
Journal British Journal of Occupational Therapy
Print ISSN 0308-0226
Electronic ISSN 1477-6006
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 83
Issue 11
Pages 674-679
Keywords Protocol, post-stroke fatigue, fatigue management, stroke, self-management, community
Public URL
Publisher URL


You might also like

Downloadable Citations