Dynamic Crystallization Pathways of Polymorphic Pharmaceuticals Revealed in Segmented Flow with Inline Powder X-ray Diffraction

Levenstein, Mark A.; Wayment, Lois; Scott, C. Daniel; Lunt, Ruth; Flandrin, Pierre-Baptiste; Day, Sarah J.; Tang, Chiu C.; Wilson, Chick C.; Meldrum, Fiona C.; Kapur, Nikil; Robertson, Karen

doi:10.1021/acs.analchem.0c00860

Dynamic Crystallization Pathways of Polymorphic Pharmaceuticals Revealed in Segmented Flow with Inline Powder X-ray Diffraction

Levenstein, Mark A.; Wayment, Lois; Scott, C. Daniel; Lunt, Ruth; Flandrin, Pierre-Baptiste; Day, Sarah J.; Tang, Chiu C.; Wilson, Chick C.; Meldrum, Fiona C.; Kapur, Nikil; Robertson, Karen

Authors

Mark A. Levenstein

Lois Wayment

C. Daniel Scott

Ruth Lunt

Pierre-Baptiste Flandrin

Sarah J. Day

Chiu C. Tang

Chick C. Wilson

Fiona C. Meldrum

Nikil Kapur

Dr KAREN ROBERTSON KAREN.ROBERTSON@NOTTINGHAM.AC.UK
ASSISTANT PROFESSOR

Citation

Levenstein, M. A., Wayment, L., Scott, C. D., Lunt, R., Flandrin, P.-B., Day, S. J., Tang, C. C., Wilson, C. C., Meldrum, F. C., Kapur, N., & Robertson, K. (2020). Dynamic Crystallization Pathways of Polymorphic Pharmaceuticals Revealed in Segmented Flow with Inline Powder X-ray Diffraction. Analytical Chemistry, 92(11), 7754–7761. https://doi.org/10.1021/acs.analchem.0c00860

Journal Article Type	Article
Acceptance Date	May 4, 2020
Online Publication Date	May 20, 2020
Publication Date	Jun 2, 2020
Deposit Date	Jul 2, 2020
Publicly Available Date	May 21, 2021
Journal	Analytical Chemistry
Print ISSN	0003-2700
Electronic ISSN	1520-6882
Publisher	American Chemical Society
Peer Reviewed	Peer Reviewed
Volume	92
Issue	11
Pages	7754–7761
DOI	https://doi.org/10.1021/acs.analchem.0c00860
Keywords	Analytical Chemistry
Public URL	https://nottingham-repository.worktribe.com/output/4501254
Publisher URL	https://pubs.acs.org/doi/10.1021/acs.analchem.0c00860
Additional Information	This document is the unedited Author’s version of a Submitted Work that was subsequently accepted for publication in Analytical Chemistry, copyright © American Chemical Society after peer review.To access the final edited and published work see https://pubs.acs.org/doi/10.1021/acs.analchem.0c00860.